Set in the world of the Inkwell Isles, The Cuphead Show! follows the misadventures of impulsive, troublemaking scamp Cuphead and cautious but easily-swayed Mugman, a pair of anthropomorphic cup brothers who live with their grandfather and elderly caretaker, Elder Kettle, in a teapot-shaped cottage. The brothers' stories often center around them trying to find their way out of various issues, occasionally meeting and interacting with characters from its video game source material. While the series is mainly episodic, one recurring plot is the Devil hunting Cuphead for his soul, as he believes it is rightfully his after Cuphead lost a soul-harvesting game called "Soul Ball", only to be always foiled by Cuphead and Mugman.