Full Publications List

1. Wi T, Choi Y, Kim J, Choi YS, Pipkin ME, and Choi J. Efficient gene deletion of Integrin alpha 4 in primary mouse CD4 T cells using CRISPR RNA pair-mediated fragmentation. Frontiers in Immunology. 2024; 15:1445341

2. Faliti CE, Mesina M, Choi J, Bélanger S, Marshall MA, Tipton CM, Hicks S, Chappa P, Cardenas MA, Mohamed AH, Thinnes TC, Cottrell C, Sharer CD, Schief WR, Nemazee D, Woodruff MC, Lindner JM, Sanz I, and Crotty S. IL-2 secreting T helper cells promote extrafollicular B cell maturation via intrinsic regulation of B cell mTOR/AKT/Blimp-1 axis. Immunity, 2024; 57(12):2772-2789.E8

3. Kim YJ#, Choi J#, and Choi YS. Transcriptional Regulation of Tfh Dynamics and Formation of Immunological Synapse. Experimental & Molecular Medicine, 2024; 56:1365-1372 #Equally contributed.

4. Yoon M, Choi Y, Wi T, Choi YS, and Choi J. The role of cGAMP via the STING pathway in modulating germinal center responses and CD4 T cell differentiation. Frontiers in Immunology. 2024; 15:1340001

5. Shehata L, Thouvenel C.D, Hondowicz B.D, Pew L. A, Pritchard G.H, Rawlings D.J, Choi J, and Pepper M. Interleukin-4 downregulates transcription factor BCL6 to promote memory B cell selection in germinal centers. Immunity, 2024;57(4):843-858.E5

6. Choi J*, Crotty S, and Choi YS*. Cytokines in Follicular Helper T Cell Biology in Physiologic and Pathologic Conditions. Immune Network, 2024;24(1):e8 *Co-corresponding authors

7. Nguyen QP, Takehara KK, Deng TZ, O'Shea S, Heeg M, Omilusik KD, Milner JJ, Quon S, Pipkin ME, Choi J, Crotty S, Goldrath AW. Transcriptional programming of CD4+ TRM differentiation in viral infection balances effector- and memory-associated gene expression. Science Immunology, 2023;8(83):eabq7486

8. Bélanger S, Haupt S, Faliti CE, Getzler A, Choi J, Diao H, Karunadharma PP, Bild NA, Pipkin ME, Crotty S. The Chromatin Regulator Mll1 Supports T Follicular Helper Cell Differentiation by Controlling Expression of Bcl6, LEF-1, and TCF-1. Journal of Immunology, 2023;210(11):1752-1760

9. Kim YJ, Oh J, Jung S, Kim CJ, Choi J, Jeon YK, Kim HJ, Kim JW, Suh CH, Lee Y, Kim SH, Crotty S, Choi YS. The transcription factor Mef2d regulates B:T synapse–dependent GC-TFH differentiation and IL–21-mediated humoral immunity. Science Immunology, 2023;8:eadf2248 

10. Kim YS, Choi J*, Lee SH*. Single-cell and spatial sequencing application in pathology. Journal of Pathology and Translational Medicine, 2023;57(1):43-51 *Co-corresponding authors

11. Choi J* and Crotty S*. Bcl6-Mediated Transcriptional Regulation of Follicular Helper T cells (TFH). Trends in Immunology, 2021;42(4):336-349 *Co-corresponding authors

12. Choi J, Diao H, Faliti CE, Truong J, Rossi M, Bélanger S, Yu B, Goldrath AW, Pipkin ME, Crotty S. Bcl-6 is the nexus transcription factor of T follicular helper cell (TFH) differentiation via repressor-of-repressor gene circuits. Nature Immunology, 2020;21(7):777-789

13. Rydyznski Moderbacher C#, Ramirez SI#, Dan JM#, Grifoni A, Hastie KM, Weiskopf D, Belanger S, Abbott RK, Kim C, Choi J, Kato Y, Crotty EG, Kim C, Rawlings SA, Mateus J, Tse LPV, Frazier A, Baric R, Peters B, Greenbaum J, Ollmann Saphire E, Smith DM, Sette A, Crotty S. Antigen-specific adaptive immunity to SARS-CoV-2 in acute COVID-19 and associations with age and disease severity. Cell, 2020;183(4):996-1012

14. Choi J, Pease DR, Chen S, Zhang B, Phee H, P21-activated kinase 2 is essential in maintenance of peripheral Foxp3+ regulatory T cells. Immunology, 2018;154(2): 309-321

15. Bae MJ#, Choi J#, Kim HK, Lim S, Kim S. PG201 protects mice from experimental autoimmune encephalomyelitis via suppression of effector T cell activation. Phytomedicine, 2018, 43: 150-157 #Equally contributed.

16. Li F, Zeng Z, Xing S, Gullicksrud JA, Shan Q, Choi J, Badovinac VP, Crotty S, Peng W, Xue HH. Ezh2 programs TFH differentiation by integrating phosphorylation-dependent activation of Bcl6 and polycomb-dependent repression of p19Arf. Nature Communications, 2018;9(1): 5452

17. O'Hagan KL, Choi J, Pryshchep O, Chernoff J, Phee H. Pak2 links TCR signaling strength to the development of regulatory T cells and maintains peripheral tolerance. Journal of Immunology, 2015;195(4):1564-1577.

18. Lee J, Choi J, Lee W, Ko K, Kim S. Dehydrodiconiferyl alcohol (DHCA) modulates the differentiation of TH17 and TH1 cells and suppresses experimental autoimmune encephalomyelitis. Molecular Immunology, 2015, 68(2):434-44

19. Lee J, Choi J, Kim S. Effective suppression of pro-inflammatory molecules by Dehydrodiconiferyl alcohol (DHCA) via IKK-NF-κB pathway, in vitro and in vivo. British Journal of Pharmacology, 2015, 172(13):3353–3369.

20. Ahn J, Jang J, Choi J, Lee J, Oh SH, Lee J, Yoon K, Kim S. GSK3β, but not GSK3α, inhibits the neuronal differentiation of neural progenitor cells as a downstream target of mTORC1. Stem Cells and Development, 2014;23(10): 1121-1133.

21. Lee DS, Choi J, Kim SH, Kim S. Ameliorating effects of HX106N, a water-soluble botanical formulation, on Aβ25-35-induced memory impairment and oxidative stress in mice. Biological & Pharmaceutical Bulletin, 2014;37(6): 954-960.

22. Choi J, Lee J, Lee J, Kim SH, Kim J, Kim S. PG201 downregulates the production of nitrite by upregulating heme oxygenase-1 expression through the control of phosphatidylinositol 3-kinase and NF-E2-related factor 2. Nitric Oxide - Biology and Chemistry, 2013;33:42-55.

23. Kim D, Choi J, Kim MJ, Kim SH, Cho SH, Kim S. Reconstitution of anti-allergic activities of PG102 derived from Actinidia arguta by combining synthetic chemical compounds. Experimental Biology and Medicine, 2013;238: 631–640.

24. Choi J, Kim SH, Kim S. Suppressive effects of PG201, an anti-arthritic botanical formulation, on lipopolysaccharide-induced inflammatory mediators in Raw264.7 cells. Experimental Biology and Medicine, 2012;237:499-508.