Tse Lab
Research Focus: Virology (CoV, DENV, and AAV)
Virology is one of the most exciting fields in biology, from the on-going COVID-19 pandemic to viral-based gene and cancer therapies. In Tse Lab, we seek to understand viral pathogenesis and transmission (zoonotic, enzootic and pandemic) at the molecular level to ultimately develop new guidelines, vaccines, and antivirals for public health measures. On the other hand, we also focus on engineering pathogenic viruses into harmless nanoparticles for medical use in gene therapy and vaccine development.
Strategies: Molecular virology, engineering and evolution
Evolution is the best engineer in nature. Inspired by the elegance of evolution, we use multiple innovative technologies (saturation-mutagenesis, directed-evolution, molecular engineering, CRISPR genome-wide screening, and multiple –omics sequencing) to recapitulate, direct, and hasten the natural viral evolution process in a controlled laboratory environment to
1) Understand viral pathogenesis and transmission by dissecting each facet of viral infection, and
2) Convert such knowledge to engineer viruses into novel nanoparticles for medical uses.
Future of science: YOU, YOU and YOU!
We believe diversity and equity is the core of society, we welcome all levels, genders, and ethnicities of students, scientists, engineers, and innovators to join our journey! Please do not hesitate to contact us!
Interesting in Joining?
The Tse lab is actively seeking postdoctoral fellows, graduate students, and research technicians. Contact us if you are interested in joining.
Contact Us
Mail:
741 Doisy Research Center
1100 South Grand Blvd.
Saint Louis University
St. Louis, MO 63104
Phone: 314-977-8862
Email: ltse001@slu.edu
Web: