Improving the Effectiveness of Drug Screening
SLU ID 22-018 | Hydrogel-based microfluidic device as a 3D in vitro drug screening platform
Intellectual Property Status
Seeking
Patent-ability under review
Know-how based
Licensee
Development partner
Commercial partner
Investment
University spin out
Background
Currently, drug screening is done on multi-well plates or arrays and on 2-D monolayer cell cultures. These drug screening approaches rely on static culture and do not include a hydrogel matrix to emulate the physiological cell environment.
Overview
Researchers at Saint Louis University have developed a hydrogel-based microfluidic device that can be used as a three dimensional in vitro drug screening platform.
Benefits
The potential benefits of this technology include:
Increasing the accuracy of simulating the physiological environment
Minimizing cell damage from shear
Minimizing cell contamination
Applications
The potential applications of this technology include:
screening drug candidates
Opportunity
Saint Louis University is seeking a partner to further develop and commercialize this technology.