Treating Atherosclerosis

SLU ID 17-013 | Induction of TcREG to Treat Atherosclerosis

Background

Atherosclerosis is the buildup of fatty deposits that can clog arteries. Estrogen is protective for the skeletal and cardiovascular systems. As such, the risk of atherogenesis increases post-menopause in women.

Overview

Researchers at Saint Louis University have demonstrated that induction of TcREG reduces atherosclerosis.

Benefits

The potential benefits of this technology include:

• Increasing the effectiveness of treatments

• Minimizing the safety risks associated with treatments

• Minimizing non-specific effects

• Minimizing immune responses to treatments

Applications

This technology has potential application for treating atherosclerosis and various resulting diseases including:

• Angina

• Carotid artery disease

• Chronic kidney disease

• Coronary heart disease

• Peripheral artery disease

Opportunity

Saint Louis University is seeking a partner to further develop and commercialize this technology.