Proprietary non-patented intellectual property
Know-how based
Licensee
Hemochromatosis is a disorder that causes harmful levels of iron to build up in the body. If untreated, hemochromatosis can lead to iron overload that can damage various parts of the body including the liver, heart, pancreas, endocrine glands, and joints. Hemochromatosis is a rare disease with fewer than 200,000 cases diagnosed in the United States each year.
Researchers at Saint Louis University (SLU) have developed a mouse model for hemochromatosis with HFE gene point mutation. This includes a variety of strains for specific types of hemochromatosis. SLU partners with The Jackson Laboratory to distribute this mouse model.
Jackson Stock Number | Description or Nomenclature
005215 | FVB.129X1(B6)-Tfr2<tm1Slu>/J
005643 | B6.129X-Gusb<tm1Sly>/J
005644 | B6.129X-Gusb<tm3Sly>/J
008217 | B6.129S1-Car4<tm1Sly>/J
008218 | B6.129S1-Car14<tm1Sly>/J
025331 | B6.129X1-Car5a<tm1Sly>/J
025570 | B6.129S1-Car5b<tm1Sly>/J
The potential advantages of this technology over existing solutions include:
Increasing the effectiveness of pre-clinical trials in identifying viable treatment alternatives.
Potential applications of this technology include the development of treatments for hemochromatosis.
Saint Louis University licenses this technology on a non-exclusive basis and partners with The Jackson Laboratory (www.jax.org) to distribute the mouse model.