Zheng Xu

Assistant Professor

Departments of Mathematics and Statistics

Wright State University

Dayton, OH, USA

Phone: 515-231-5646

Email: zheng [DOT] xu [DOT] isu [AT] gmail [DOT] com

Google Scholar: https://scholar.google.com/citations?user=OzNHuxcAAAAJ&hl=en

Wright State Profile: https://people.wright.edu/zheng.xu

Github Profile: https://github.com/zhengxu0459

Education & Training

    • Postdoc. University of North Carolina at Chapel Hill, Bio-statistics and Genetics, Chapel Hill, NC, 2012-2016

Adviser: Prof. Yun Li

    • Ph.D. Iowa State University, Statistics and Economics, Ames, IA, 2012

Advisers: Prof. Song Xi Chen and Prof. David Hennessy

    • M.Sc. Illinois State University, Applied Economics, Normal, IL, 2005

    • B.Econ. Fudan University, International Economics with the minor in Computer Science, Shanghai, China, 2001

Research Interest

  • Biostatistics, Statistical Genetics, Genetic Epidemiology, Bioinformatics, Genome Structure

  • Machine Learning, Prediction, Nonparametric Methods, Time Series, Stochastic Process

  • Agricultural Statistics, Econometrics, Financial Statistics, Plant Image Phenotyping

Working Experience

  • Assistant Professor, Department of Mathematics and Statistics, Wright State University, Dayton, OH, 2019-now

  • Research Assistant Professor, Department of Statistics, University of Nebraska-Lincoln, Lincoln, Nebraska, 2016-2019

  • Postdoctoral Research Associate , Departments of Biostatistics and Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 2012-2016

  • Risk Analyst Intern, Noble Americas Company, Stamford, CT, 2011

  • Teaching Assistant and Research Assistant, Department of Statistics, Iowa State University, Ames, IA 2009-2012

  • Teaching Assistant, Department of Economics, Iowa State University, Ames, IA 2005-2009

  • Graduate Assistant, Department of Economics, Illinois State University, IL 2003-2005

  • Securities Analyst and Webmaster, Shanghai Securities Consulting Company, Shanghai, China, 2003

Published Articles and Accepted Articles

  1. H Zhao, Y Zhan, Z Xu, JJ Nduwamungu, Y Zhou, R Powers, C Xu, in press, The application of machine-learning and Raman spectroscopy for the rapid detection of edible oils type and adulteration, Food Chemistry.

  2. H Dai, L Henriksen, Z Xu, N Rathnayake, in press, Using place-based characteristics to inform FDA tobacco sales inspections: Results from a multi-level propensity score model, Tobacco Control.

  3. Y Gu, X Guo, P Liu, G Li, C Huang, F Guo, G Hu, C Wu, Z Xu, X Yang, P Liu, in press, Preparation of ribosomal protein S14 polyclonal antiboday in broiler pulmonary artery: Its application in broiler ascites syndrome, International Journal of Biological Macromolecules.

  4. L Huang, X Guo, P Liu, Y Zhao, C Wu, C Zhou, C Huang, G Li, Y Zhuang, S Cheng, H Cao, C Zhang, Z Xu, X Liu, G Hu, P Liu, (in press), Correlation between acute brain injury and brain metabonomics in dichlorvos-poisoned broilers, Journal of Hazardous Materials.

  5. Y Gu, G Li, C Huang, P Liu, G Hu, C Wu, Z Xu, X Guo, P Liu, (in press), Dichlorvos poisoning caused chicken cerebrum tissue damage and related apoptosis-related gene changes, Science of the Total Environment.

  6. W Chen, P Liu, Y Zhao, C Zhou, G Li, X Guo, C Huang, G Hu, C Wu, Z Xu, Z Yang, A Khan, P Liu, 2021. Clinico-Pathological, immunohistochemical and in-situ TUNEL assay observations of canine breast tumors. Pakistan Veterinary Journal.

  7. Y Zhao, Y Zhuang, Y Shi, Z Xu, C Zhou, L Guo, P Liu, C Wu, R Hu, G Hu, X Guo, L Xu, (in press), Effects of N-acetyl-l-cysteine on heat stress-induced oxidative stress and inflammation in the hypothalamus of hens, Journal of Thermal Biology.

  8. T Wang, Y Fan, Z Xu, S Kumar, B Kasu, (in press), Adopting cover crops and buffer strips to reduce nonpoint source pollution: Understanding the farmers’ perspectives in the U.S. Northern Great Plains, Journal of Soil and Water Conservation.

  9. L Huang, X Qian, C Wu, P Liu, Y Zhao, Z Xu, P Liu, (in press), Diagnosis and treatment of a cat with immune mediated hemolytic anemia (IMHA), Agrobiological Records.

  10. Q Zhang, Z Xu, Y Lai, (in press), An empirical Bayes approach for the identification of long-range chromosomal interaction from Hi-C data, Statistical Applications in Genetics and Molecular Biology.

  11. J Singh, T Wang, S Kumar, Z Xu, P Sexton, J Davis, A Bly, (in press), Crop yield and economics of cropping systems featuring different rotations, tillage, and cover crops, Journal of Soil and Water Conservation.

  12. T Wang, Z Xu, D Kolady, JD Ulrich-Schad, D Clay, (in press), Cover crops usage in south Dakota: farmer perceived profitability and future adoption decisions. Journal of Agricultural and Resource Economics.

  13. AE Saak, T Wang, Z Xu, Kolady D, JD Ulrich-Schad, D Clay, (in press), Duration of usage and farmer reported benefits of conservation tillage. Journal of Soil and Water Conservation.

  14. H Dogan, J Shu, Z Hakguder, Z Xu, J Cui, 2020, Elucidation of molecular links between obesity and cancer through microRNA regulation, BMC Medical Genomics, 13, 161.

  15. S Cheng, X Liu, P Liu, G Li, X Guo, G Hu, L Li, C Wu, Z Xu, Q Zhou, J Jiang, S Luo, H Huang, P Liu, 2020, Dysregulated expression of mRNA and SNP in pulmonary artery remodeling in ascites syndrome in broilers, Poultry Science, 100877.

  16. L Lu, X Liu, WK Huang, P Giusti-Rodriguez, J Cui, S Zhang, W Xu, Z Wen, S Ma, JD Rosen, Z Xu, C Bartels, R Kawaguchi, M Hu, PC Scacheri, Z Rong, Y Li, PF Sullivan, H Song, G Minf, Y Li, ,F Jin, 2020, Robust Hi-C Maps of Enhancer-Promoter Interactions Reveal the Function of Non-coding Genome in Neural Development and Diseases, Molecular Cell, 79, 521-534.

  17. H Zhao, Y Zhan, Z Xu, JJ Nduwamungu, Y Zhou, C Xu, 2020, Machine learning-driven Raman spectroscopy for rapidly detecting type, adulteration, and oxidation of edible oils, INFORM, 31 (4), 12-15. https://doi.org/10.21748/inform.04.2020.12.

  18. X Dai, Z Xu, Z Liang, X Tu, S Zhong, J Schnable, P Li, 2020, Non-homology-based prediction of gene functions in maize (Zea mays ssp. mays), Plant Genome, 13, e20015, https://doi.org/10/1002/tpg2.20015.

  19. J Chen, Y Mao, C Xing, R Hu, Z Xu, H Cao, J Luo, 2020, Traditional Chinese medicine prescriptions decrease diarrhea rate by relieving colonic inflammation and ameliorating caecum microbiota in piglets, Evidence-Based Complementary and Alternative Medicine, 2020, 3647525, https://doi.org/10.1155/2020/3647525.

  20. Y Zhao, C Zhou, C Wu, X Guo, G Hu, Q Wu, Z Xu, G Li, H Cao, L Li, V Latigo, P Liu, S Cheng, P Liu, 2020, Subchronic oral mercury caused intestinal injury and changed gut microbiota in mice, Science of The Total Environment, 721, 137639.

  21. Y Xiao, X Zheng, G Li, C Zhou, C Wu, Z Xu, G Hu, X Guo, L Li, H Cao, V Latigo, P Liu, 2020, Investigation of the effects of dichlorvos poisoning on AMPK signaling pathway in chicken brain tissues, Environmental Pollution, 261, 114109.

  22. C Miao, A Pages, Z Xu, E Rodene, J Yang and J Schnable, 2020, Semantic segmentation of sorghum organs using hyperspectral data identifies genetic associations, Plant Phenomics, 2020, 4216373. https://doi.org/10.34133/2020/4216373.

  23. M Li, NK Wijewardane, Y Ge, Z Xu, MR Wilkins, 2020, Visible/near infrared spectroscopy and machine learning for predicting polyhydroxybutyrate production cultured on alkaline pretreated liquor from corn stover, Bioresource Technology Reports, 9, 100386.

  24. J Reinhardt, JJ Romine and Z Xu, 2020, Factors contributing to student satisfaction with dental loupes and headlights, European Journal of Dental Education, 24, 266-271.

  25. S Cheng, H Mao, Y Ruan, C Wu, Z Xu, G Hu, X Guo, C Zhang, H Cao and P Liu, 2020, Copper changes intestinal microbiota in the cecum and rectum in mice by 16S rRNA gene sequencing, Biological Trace Element Research, 193, 445-455.

  26. J Mo, F Wang, Z Xu, C Feng, X Tang and X Shen, 2019, Characterization and performance of soy protein isolate modified by tyrosinase, International Adhesion and Adhesives, 92, 111-118.

  27. Y Ruan, C Wu, X Guo, Z Xu, C Xing, H Cao, C Zhang, G Hu, P Liu, 2019, High doses of copper and mercury changed cecal microbiota in female mice, Biological Trace Element Research, 189, 134-144.

  28. C Feng, F Wang, Z Xu, Y Fang, X Tang, X Shen, 2018, Characterization and adhesion properties of soybean proteins modified by xanthan gum, Coatings, 8, 342.

  29. Z Xu, Q Duan, J Cui, Y Qiu, Q Jia, C Wu and J Clarke, 2018, Analysis of genetic and non-genetic factors influencing triglycerides-lowering fenofibrate drug effects based on paired observations, BMC Proceedings, 12, 46.

  30. WE Huffman, Y Jin and Z Xu, 2018, The economic impacts of technology and climate change: new evidence unearthed from crop yields, Agricultural Economics, 49, 463-479.

  31. Z Xu, C Valdes and J Clarke, 2018, Existing and potential statistical and computational approaches for the analysis of 3D CT images of plant roots, Agronomy, 8, 71.

  32. Q Duan, Z Xu, L Raffield, S Chang, D Wu, EM Lange, AP Reiner and Y Li, 2018, A robust and powerful two-step testing procedure for local ancestry adjusted allelic association analysis in admixed populations, Genetic Epidemiology, 42, 288-302.

  33. H Lin, H Mao, S Cheng, M Yi, Y Ruan, C Wu, Z Xu, G Hu, X Guo, H Cao, L Li, Y Han and P Liu, 2018. Detection of Actinobacillus pleuropneumoniae through duplex PCR based on apxia and apxiva genes. Pakistan Veterinary Journal, 38, 276-280.

  34. J Shu, BVR Silva, T Gao, Z Xu and J Cui, 2017, Dynamic and modularized microRNA regulation and its implication in human cancers, Scientific Report, 7, 13356.

  35. ME Cannon, Q Duan, Y Wu, M Zeynalzadeh, Z Xu, AJ Kangas, P Soininen, M Ala-Korpela, M Civelek, AJ Lusis, J Kuusisto, FS Collins, M Boehnke, H Tang, M Laakso, Y Li and KL Mohlke, 2017, Trans-ancestry fine mapping and molecular assays identify regulatory variants at the ANGPTL8 HDL-C GWAS locus, G3: Genes, Genomes, Genetics, 7, 3217-3227.

  36. H Chen, Z Xu, J Mo, Y Lyu, X Tang and X Shen, 2017, Effect of guar gum on adhesion properties of soybean protein isolate onto porcine bones, International Journal of Adhesion and Adhesives, 75, 124-131.

  37. J Martin, Z Xu, AP Reiner, KL Mohlke, P Sullivan, B Ren, M Hu and Y Li, 2017, HUGIn: Hi-C Unifying Genomic Interrogator. Bioinformatics, 33, 3793-3795.

  38. Z Xu, 2016, An alternative circular smoothing method to nonparametric estimation of periodic functions, Journal of Applied Statistics, 43, 1649-1672.

  39. C Wu, Z Xu and K Huang, 2016, Effects of dietary selenium on inflammation and hydrogen sulfide in the gastrointestinal tract in chickens, Biological Trace Element Research, 174, 428-435.

  40. AD Schmitt, M Hu, I Jung, Z Xu, Y Qiu, CL Tan, Y Li, CL Barr and B Ren, 2016, A compendium of chromatin contract maps reveal frequently interacting regions in the human genome, Cell Reports, 17, 2042-2059.

  41. C Wu, Z Xu, R Gai and K Huang, 2016, Matrine ameliorates spontaneously developed colitis in Interleukin-10-deficient mice, International Immunopharmacology, 36, 256-262.

  42. G Zhang, KC Huang, Z Xu, JY Tzeng, KN Conneely, W Guan, J Kang and Y Li, 2016, Across-platform imputation of DNA methylation levels using penalized functional regression, Genetic Epidemiology, 40, 333-340.

  43. Z Xu, G Zhang, C Wu, M Hu and Y Li, 2016, Fast-HiC: a fast and accurate algorithm to detect long-range chromosomal interactions from Hi-C data, Bioinformatics, 32, 2692-2695.

  44. Z Xu, Q Duan, G Zhang, S Chai, B Zhang, C Wu, F Jin, F Yue, Y Li and M Hu, 2016, HiView: An integrative genome browser to leverage Hi-C results for the interpretation of GWAS data, BMC Research Notes, 9, 159.

  45. Z Xu, G Zhang, F Jin, M Chen, TS Furey, PF Sullivan, Z Qin, M Hu and Y Li, 2015, A hidden Markov random field-based Bayesian method for the detection of long-range chromosomal interactions in Hi-C data, Bioinformatics, 32, 650-656.

  46. S Yan, S Yuan, Z Xu, B Zhang, B Zhang, G Kang, A Byrnes and Y Li, 2015, Likelihood based complex trait association testing for arbitrary depth sequencing data, Bioinformatics, 31, 2955-2962.

  47. Z Xu, Q Duan, SYan, W Chen, M Li, E Lange and Y Li, 2015, DISSCO: Direct imputation of summary statistics allowing covariates, Bioinformatics, 31, 2434-2442.

  48. SX Chen and Z Xu, 2014, On implied volatility for options – Some reasons to smile and more to correct, Journal of Econometrics, 179, 1-15.

  49. J Kang, KC Huang, Z Xu, Y Wang, GR Abecasis and Y Li, 2013, AbCD: Arbitrary coverage design for sequencing-based genetic studies, Bioinformatics, 29, 799-801.

  50. SX Chen and Z Xu, 2013, On smoothing estimation for seasonal time series with long cycles, Statistics and Its Interface, 6, 435-447.

  51. Z Xu, 2013, Estimation of parametric homogeneous stochastic volatility pricing formulae based on option data, Economics Letters, 120, 369-373.

  52. Z Xu, DA Hennessy, K Sardana and G Moschini, 2013, The realized yield effect of genetically engineered crops: U.S. maize and soybean, Crop Science, 53, 735-745.

  53. X Zheng and Z Xu, 2000, Financial sector: Rediscovery of investment value, Modern Enterprise Herald, 10, 42-49. (In Chinese, Core Chinese Economics Journal).

Published Book Chapter

  1. Z Xu and W Cu, 2020, Machine learning and statistical approaches for plant phenotyping, Intelligent Image Analysis for Plant Phenotyping, edited by A Samal and SD Choudury, CRC Press, https://doi.org/10.1201/9781315177304. (Book Chapter).

Published Book Reviews

  1. Z Xu, 2017, Andy Hector (2015): the new statistics with R: an introduction for biologists. Oxford University Press, 224 pp., $125.00 (hardcover), $49.95 (paper), ISBN 978-0-19-872906-8, Statistical Papers, 58, 553-554.

  2. Z Xu, 2017, Martin Bland (2015): An introduction to medical statistics Oxford University Press, 4th edition, 464 pp., $49.95 (paper), ISBN 978-0-19-958992-0, Statistical Papers, 58, 953-954.

Manuscripts in Revision or Under Review

  1. C Miao, TP Hoban, A Pages, Z Xu, E Rodene, J Ubbens, I Stavness, J Yang, J Schnable, Simulated plant images improve maize leaf counting accuracy, https://doi.org/10.1101/706994

  2. L Sun, F Wang, Z Xu, Z Weng, Y Fang, X Tang, T Zhao and X Shen, Study on soybean oil quality evaluation method and establishment of model for suitable soybean varieties for soybean oil processing.

  3. Z Xu, X Zheng, Y Wang, B Zhang and C Wu, The impacts of margin trading in the framework of testing weak-form efficient market hypothesis: evidence from convertible bond markets in China.

  4. Z Xu, S Yan, C Wu and Q Duan, Association testing of a group of genetic markers based on next generation sequencing data with arbitry depth.

  5. R Yu, G Hmimina, Y Wang, A Lyapustin, KF Huemmrich, D Billesbach, J Zhang, Z Xu, J Garmon, Reducing angular effects in high-latitude MODIS MAIAC reflectance using random forests.

Academic Services

  • Associate Editor (2016-) for Statistical Papers

  • Associate Editor (2022-) for Journal of Statistical Computation and Simulation

  • Guest Associate Editor (2017-2018) and Associate Editor (2018-) for Statistical Analysis and Data Mining

  • Academic Editor (2021-) for PLOS ONE

  • Associate Editor (2017-) for Bio-Med Central (BMC) Research Notes

  • Reviewer for Journals: Statistical Sinica; Biometrics; Journal of Business and Economics Statistics; Bioinformatics; Journal of Applied Statistics; Human Genetics; Gene; PLOS One; Scientific Reports; BMC Health Services Research; Public Health Nutrition; Journal of Financial Economic Policy; China Health Review; Journal of Finance and Economics; Frontiers in Public Health, section Epidemiology; Journal of Finance and Accounting; Journal of Agricultural Science and Technology; etc.

  • Reviewer for Conference: Genetic Analysis Workshop (GAW) 20

Conferences

  • Detect chromatin interaction from multiple Hi-C datasets by hierarchical hidden Markov random field model (Paper Presentation), International Chinese Statistical Association Applied Statistics Symposium 2016

  • Rare variant test based on next-generation sequencing data with arbitrary length (Paper Presentation), Joint Statistical Meetings 2016

  • A hidden Markov random field based Bayesian method for the detection of long-range chromosomal interactions in Hi-C Data (Poster), American Society of Human Genetics 2015

  • Comparison of alignment strategies for allelic expression imbalance (Poster), American Society of Human Genetics 2015

  • Development of statistical methods and bioinformatics tools for genome-wide chromosome interaction data (Poster), Second Annual Research Symposium 2015

  • Alternative peak calling methods on Hi-C data accommodating the whole spectrum of dispersion (Poster), American Society of Human Genetics 2014

  • A HMRF-based Bayesian method for chromatin interaction calling (Paper Presentation), Joint Statistical Meetings 2014

  • Econometric estimates of the contribution of genetic modification to yield potential and damage control: evidence from state average corn yields (Paper Presentation), Symposium and Festschrift in Honor of Wallace Huffman

  • Some reasons to smile: implied volatilities in presence of pricing error (Paper Presentation), Joint Statistical Meetings 2010

  • Have biotech seeds increased maize yields (Poster), Agricultural and Applied Economic Association Meeting 2010

Computer Skills

    • Engineering programing by JAVA, C/C#/C++, PYTHON, MATLAB, Mathematica and Perl.

    • Statistical and econometric programing by R, SAS, GAUSS, STATA and TSP.

    • Bloomberg interface, Logical Information Machine, XML, SQL, ArcGIS and Excel VBA.

    • Website programing by HTML, PHP and JavaScript.

    • Rich experience in handling large data and Linux server.

Certifications

    • Oracle Certified Professional JAVA SE Programmer (OCPJP) Certification (96% in JAVA 6).

    • Certified Financial Analyst (CFA) Exam 1.

    • Associate of the Society of Actuaries (ASA) All Required Exams: (i) Probability, (ii) Financial Mathematics, (iii) Models for Life Contingencies, (iv) Construction and Evaluation of Actuarial Models and (v) Models for Financial Economics.

Awards

  • T.A. Bancroft Award, Department of Statistics, Iowa State University, 2010.

  • People’s Scholarship, Fudan University, 1998.

Try - Nov 05, 2015 1:55:50 AM