Profile:
2016/10- present Assistant Professor Graduate School of Medicine and Faculty of Medicine Kyoto University
2015/4 - 2016/9   Senior Researcher Simulation-Driven Drug Discovery Group, Foundation for Biomedical Research and Innovation
2012/4 - 2015/3   Postdoctoral fellow Medical Institute of Bioregulation, Kyushu University.

2011/4 - 2012/3   Postdoctoral fellow Department of Intelligence Science and Technology, Kyoto University.
2008/4 - 2011/3   Ph.D. Department of Intelligence Science and Technology, Kyoto University.
2006/4 - 2008/3   M.S. Department of Information Science and Technology, Hokkaido University.
2002/4 - 2006/3   B.S. Faculty of Engineering, Kyoto University.

Papers:
Masatoshi Hamanaka, Kei Taneishi, Hiroaki Iwata, Jun Ye, Jianguo Pei, Jinlong Hou, Yasushi Okuno,
"CGBVS‐DNN: Prediction of Compound‐protein Interactions Based on Deep Learning,"
Molecular Informatics, In press

Michio Iwata, Ryusuke Sawada, Hiroaki Iwata, Masaaki Kotera, Yoshihiro Yamanishi,
"Elucidating the modes of action for bioactive compounds in a cell-specific manner by large-scale chemically-induced transcriptomics,"
Scientific Reports, 7:40164 (2017).
Full Text

Hiroaki Iwata
, Ryusuke Sawada, Sayaka Mizutani, Masaaki Kotera, Yoshihiro Yamanishi,

"Large-Scale Prediction of Beneficial Drug Combinations Using Drug Efficacy and Target Profiles,"
Journal of chemical information and modeling. 55.12 (2015): 2705-2716. Full Text

Ryusuke Sawada, Hiroaki Iwata, Sayaka Mizutani, Yoshihiro Yamanishi,
"Target-based drug repositioning using large-scale chemical-protein interactome data,"
Journal of chemical information and modeling. 55.12 (2015): 2717-2730. Full Text

Kazuhiro Sakamaki, Naoyuki Iwabe, Hiroaki Iwata, Kenichiro Imai, Chiyo Takagi, Kumiko Chiba, Chisa Shukunami, Kentaro Tomii, Naoto Ueno,
"Conservation of structure and Function in vertebrate c-FLIP proteins despite rapid evolutionary change,"
Biochemistry and Biophysics Reports 3 (2015): 175-189. Full Text

Hiroaki Iwata
, Ryusuke Sawada, Sayaka Mizutani, Yoshihiro Yamanishi,
"Systematic Drug Repositioning for a Wide Range of Diseases with Integrative Analyses of Phenotypic and Molecular Data,"
Journal of chemical information and modeling, 55.2 (2015): 446-459. Full Text

Kazuhiro Sakamaki, Kouhei Shimizu, Hiroaki Iwata, Kenichiro Imai, Yutaka Satou, Noriko Funayama, Masami Nozaki, Mamiko Yajima, Osamu Nishimura, Mayura Higuchi, Kumiko Chiba, Michi Yoshimoto, Haruna Kimura, Andrew Y. Gracey, Takashi Shimizu, Kentaro Tomii, Osamu Gotoh, Koji Akasaka, Tatsuya Sawasaki, David J. Miller,
"The apoptotic initiator caspase-8: its functional ubiquity and genetic diversity during animal evolution,"
Molecular Biology and Evolution, (2014): msu260. Full Text

Hiroaki Iwata*, Sayaka Mizutani*, Yasuo Tabei, Masaaki Kotera, Susumu Goto, Yoshihiro Yamanishi,
"Inferring protein domains associated with drug side effects based on drug-target interaction network,"
BMC Systems Biology 7.Suppl 6 (2013): S18. (* Joint first author) Full Text

Hiroaki Iwata
, Osamu Gotoh,
"Benchmarking spliced alignment programs including Spaln2, an extended version of Spaln that incorporates additional species-specific features,"
Nucleic Acids Research, 40, (20): e161 (2012). Full Text

Hiroaki Iwata
, Osamu Gotoh,

"Comparative analysis of information contents relevant to recognition of introns in many species,"
BMC Genomics 2011, 12:45 (19 January 2011). Full Text

Oral Presentations:
Hiroaki Iwata*, Sayaka Mizutani*, Yasuo Tabei, Masaaki Kotera, Susumu Goto, Yoshihiro Yamanishi,
"Inferring protein domains associated with drug side effects based on drug-target interaction network,"
Genome Informatics Workshop (GIW2013), Singapore, Singapore, 2013/12.


Hiroaki Iwata, Osamu Gotoh,
"Evaluation of Spliced Alignment Programs using Cross-Species Benchmark Datasets,"
Proc. the 2011 Annual Conference of Japanese Society for Bioinformatics (JSBi 2011), Kobe, Japan, 2011/11.


Hiroaki Iwata, Osamu Gotoh,
"Comparative analysis of information contents relevant to intron recognition in many species,"
3rd Asian Young Researchers Conference for Computational and Omics Biology (AYRCOB2010), Tainan, Taiwan, 2010/3.


Poster Presentations:
Hiroaki Iwata, Minako Yoshihara, Yoshihiro Yamanishi,
"Computational drug repositioning by prediction drug-disease association network"
Proc. the 2013 Annual Conference of Japanese Society for Bioinformatics (JSBi 2013), Tokyo, Japan, 2013/10.

Hiroaki Iwata, Minako Yoshihara, Yoshihiro Yamanishi,
"Predicting drug-disease association network toward drug repositioning,"
Computational Biology Research Center Workshop 2013 (CBRC2013), Tokyo, Japan, 2013/9.

Hiroaki Iwata, Osamu Gotoh,
"Evaluation of Spliced Alignment Programs Including an Extended Version of Spaln,"
The 10th Korea-China-Japan Bioinformatics Training Course, Jeju island, Korea, 2011/5.

Hiroaki Iwata, Osamu Gotoh,
"Evaluation of Spliced Alignment Programs Including an Extended Version of Spaln,"
The 2010 Annual Conference of Japanese Society for Bioinformatics (JSBi2010), Fukuoka, Japan, 2010/12.

Hiroaki Iwata, Osamu Gotoh,
"Evaluation of Spliced Alignment Programs for Long Sequence Reads,"
Computational Biology Research Center Workshop 2010 (CBRC2010), Tokyo, Japan, 2010/7.

Hiroaki Iwata, Osamu Gotoh,
"Comparative analysis of information contents relevant to intron recognition in many species,"
Genome Informatics Workshop (GIW2009) , Yokohama, Japan, 2009/12.