Yi Zhang


Current Appointment
Instructor                                                                                                                                                                                                                  
03/2016 - Present
Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA 

Education and Training
Postdoctoral Fellow                                                                                                                                                                                                 06/2014 - 02/2016
Johns Hopkins University School of Medicine
Ph.D. in Electrical and Computer Engineering                                                                                                                                                      09/2009 - 06/2014
Johns Hopkins University, Baltimore, MD, USA
B.S. in Electrical Engineering                                                                                                                                                                                 09/2015 - 06/2009
Zhejiang University, Hangzhou, Zhejiang, China
Expertise
Chemical Exchange Saturation Transfer (CEST), Magnetic Resonance Spectroscopy (MRS), Image Reconstruction, Spectroscopic localization, Parallel imaging, Compressed sensing

Awards and Honors
Magna Cum Laude Merit Award, International Society for Magnetic Resonance in Medicine                                                                                                  05/2016
Magna Cum Laude Merit Award, International Society for Magnetic Resonance in Medicine                                                                                                  05/2016
Summa Cum Laude Merit Award, International Society for Magnetic Resonance in Medicine                                                                                                 05/2015
Junior Fellow, International Society for Magnetic Resonance in Medicine                                                                                                                                02/2015
Magna Cum Laude Merit Award, International Society for Magnetic Resonance in Medicine                                                                                                   04/2013
Magna Cum Laude Merit Award, International Society for Magnetic Resonance in Medicine                                                                                                   03/2012
Educational Stipend Award, International Society for Magnetic Resonance in Medicine                                                                                                    2011 - 2013
First prize in China Undergraduate Mathematical Contest in Modeling                                                                                                                                     12/2007
Professional Societies
Ad Hoc Committee on Standards in Quantitative, International Society for Magnetic Resonance in Medicine                                                         2015 - 2016
Trainee member, Radiological Society of North America                                                                                                                                           03/2013 - Present
Trainee member, International Society for Magnetic Resonance in Medicine                                                                                                           11/2010 - Present
Patent Applications
1. Zhang Y, Zhou JBottomley PA, Method of Fast Imaging of NMR Parameters with Variably-accelerated Sensitivity Encoding (vSENSE). (US 62/320,197)
2. Zhang Y, Zhou J, Bottomley PA, System and Method of Obtaining Spatially-encoded NMR Parameters from Arbitrarily-shaped Compartments and Linear Algebraic Modeling. (US 14/715,367) 
3. Bottomley PA, Zhang Y, Hegde SS, Methods and Apparatus for Accelerated, Motion-corrected High-resolution MRI Employing Internal Detectors or MRI Endoscopy. (US 61/800,485) 
4. Bottomley PA, Gabr RE, Weiss RG, Zhang Y, System and Method of Performing Magnetic Resonance Spectroscopic Imaging. (US 61/466,188)
Publications
Book chapter:
1. Bottomley PA and Zhang Y. Accelerated Spatially-Encoded MRS of Arbitrarily-Shaped Compartments Using Linear Algebraic Modeling. In: Bottomley PA, Griffiths JR, editors. Handbook of Magnetic Resonance Spectroscopy In Vivo: MRS theory, practice and applications. Chichester: John Wiley; 2016.
2. Zhou J, Zhang Y, Jiang S, Lee D, Zhao X, Heo H. Principles and Applications of Amide Proton Transfer (APT) Imaging. In: McMahon M, Gilad A, Bulte J, van Zijl PCM, editors. Chemical Exchange Saturation Transfer Imaging: Advances and Applications. Pan Stanford Publishing Pte Ltd; 2017.
Journal:
1. Zhang Y, Liu X, Zhou J, Bottomley PA. Ultrafast compartmentalized relaxation time mapping with linear algebraic modeling. Magnetic Resonance in Medicine. 2017; DOI: 10.1002/mrm.26675.
2. Song G, Li C, Luo X, Zhao X, Zhang S, Zhang Y, Jiang S, Wang X, Chen Y, Chen H, Gong T, Zhou J, Chen M. Evolution of Cerebral Ischemia Assessed by Amide Proton Transfer-Weighted MRI. Frontiers in Neurology. 2017; DOI: 10.3389/fneur.2017.00067.
3. Zhang H, Wang W, Jiang S, Zhang Y, Heo HY, Wang X, Peng Y, Wang J, Zhou J. Amide proton transfer-weighted MRI detection of traumatic brain injury rats. Journal of Cerebral Blood Flow & Metabolism. 2017; DOI: 10.1177/0271678X17690165.
4. Zhang Y, Heo HY, Lee DH, Jiang S, Zhao X, Bottomley PA, Zhou J. Chemical Exchange Saturation Transfer (CEST) Imaging with Fast Variably-accelerated Sensitivity Encoding (vSENSE). Magnetic Resonance in Medicine, 2016; DOI: 10.1002/mrm.26307.
5. Heo H, Lee D,  Zhang YZhao X, Jiang S, Zhou J. Insight into the quantitative Metrics of Chemical Exchange Saturation Transfer (CEST) Imaging. Magnetic Resonance in Medicine. 2016; DOI: 10.1002/mrm.26264
6. Yang Y, Lee DH, Peng SL, Zhang K, Zhang Y, Jiang S, Zhao X, Heo HY, Wang X, Chen M, Lu H, Li H, Zhou J. Assessment of Glioma Response to Radiotherapy Using Multiple MRI Biomarkers with Manual and Semiautomated Segmentation Algorithms. Journal of Neuroimaging. 2016; DOI: 10.1111/jon.12354.
7. Heo H, Zhang Y, Lee D, Jiang S, Zhao X, Zhou J. Accelerating Chemical Exchange Saturation Transfer (CEST) MRI by Combining Compressed Sensing and Sensitivity Encoding Techniques. Magnetic Resonance in Medicine. 2016; DOI: 10.1002/mrm.26141. 
8. Ma B, Blakeley J, Hong X, Zhang H, Jiang S, Blair L, Zhang Y, Heo H, Zhang M, Zhou J. Applying amide proton transfer MR imaging to distinguish pseudoprogression from true progression in malignant gliomas. Journal of Magnetic Resonance Imaging. 2016; DOI: 10.1002/jmri.25159.
9. Zhang H, Kang H, Zhao X, Jiang S, Zhang Y, Zhou J, Peng Y. Amide Proton Transfer (APT) MR Imaging and Magnetization Transfer (MT) MR Imaging of Pediatric Brain Development. European Radiology. 2016; DOI: 10.1007/s00330-015-4188-z.
10. Lee D, Heo H, Zhang K, Zhang Y, Jiang S, Zhao X, Zhou J. Quantitative Assessment of the Effects of Water Proton Concentration and Water T1 Changes on Amide Proton Transfer (APT) and Nuclear Overhauser Enhancement (NOE) MRI: The Origin of the APT Imaging Signal in Brain Tumor. Magnetic Resonance in Medicine. 2016; DOI: 10.1002/mrm.26131.
11. Zhang Y, Heo H, Lee D, Zhou J. On the selection of reference images used for registration in CEST imaging. Journal of Magnetic Resonance Imaging. 2016; 43(3):756-61.
12. Heo H, Zhang Y, Lee D, Hong X, Zhou J. Quantitative Assessment of Amide Proton Transfer (APT) and Nuclear Overhauser Enhancement (NOE) Imaging with Extrapolated Semi-solid Magnetization Transfer Reference (EMR) Signals: Application to a Rat Glioma Model at 4.7 T. Magnetic Resonance in Medicine. 2016; 75(1):137-49.
13. Jiang S, Yu H, Wang X, Lu S, Li Y, Feng L, Zhang Y, Heo H, Lee D, Zhou J, Wen Z. Molecular MRI differentiation of primary central nervous system lymphomas and high-grade gliomas: Diagnostic performance of endogenous protein-based amide proton transfer imaging at 3 Tesla. European Journal of Radiology. 2016; 26(1):64-71.
14. Zhang Y, Heo H, Lee D, Jiang S, Bottomley PA, Zhou J. Highly-accelerated chemical exchange saturation transfer (CEST) measurements with linear algebraic modeling. Magnetic Resonance in Medicine. 2015; DOI: 10.1002/mrm.25873.
15. Heo H, Zhang Y, Jiang S, Lee D, Zhou J. Quantitative assessment of amide proton transfer (APT) and nuclear Overhauser enhancement (NOE) imaging with extrapolated semi-solid magnetization transfer reference (EMR) signals: II. Comparison of Three EMR Models and Application to Human Brain Glioma at 3 T. Magnetic Resonance in Medicine. 2015; DOI: 10.1002/mrm.25795.
16. Wang M, Hong X, Chang C, Li Q, Ma B, Zhang H, Xiang S, Heo H, Zhang Y, Lee D, Leigh R, Raymond K, van Zijl P, Wang J, Zhou J. Simultaneous detection and separation of hyperacute intracerebral hemorrhage and cerebral ischemia using amide proton transfer (APT) MRI. Magnetic Resonance in Medicine. 2015; 74:42-50.
17. Kun Y, Fu Z, Yang C, Zhang K, Jiang S, Lee D, Heo H, Zhang Y, Cole R, van Eyk J, Zhou J. Assessing Amide Proton Transfer (APT) MRI Contrast Origins in 9L Gliosarcoma in the Rat Brain Using Proteomic Analysis. Molecular Imaging and Biology. 2015; 17(4):479-87.
18. Bottomley PA, Zhang Y. Accelerated spatially-encoded spectroscopy of arbitrarily shaped compartments using prior knowledge and linear algebraic modeling. Encyclopedia of Magnetic Resonance. 2015; 4:89-104.
19. Zhang Y, Zhou J, Bottomley PA. Minimizing lipid signal bleed in brain 1H chemical shift imaging by post-acquisition grid shifting. Magnetic Resonance in Medicine. 2015; 74:320-329.
20. Hegde SS, Zhang Y, Bottomley PA. Acceleration and motion-correction techniques for high-resolution intravascular MRI. Magnetic Resonance in Medicine. 2015; 74(2):452-61.
21. Zhang Y, Gabr RE, Zhou J, Weiss RG, Bottomley PA. Highly-accelerated quantitative 2D and 3D localized spectroscopy with linear algebraic modeling (SLAM) and sensitivity encoding. Journal of Magnetic Resonance. 2013; 237:125-138.
22. Zhang Y, Gabr RE, Schär M, Weiss RG, Bottomley PA. Magnetic resonance Spectroscopy with Linear Algebraic Modeling (SLAM) for higher speed and sensitivity. Journal of Magnetic Resonance. 2012; 218:66-76.

Last updated 02/2017