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Dr. Yina Wei (魏依娜)
Position: Principal Investigator, Zhejiang Lab
E-mail: weiyina039@gmail.com
Google Scholar: https://scholar.google.com/citations?user=o6NB0FwAAAAJ&hl=en
Research Interests:
Brain computer interface
Design and conducting biophysically model to understand how the brain works in health (such as sleep, visual system) and disease (such as epilepsy and spreading depression)
Analyze the data using statistical analysis and machine learning techniques
Brain-inspired Intelligence
News:
My recent research on "Associations between in vitro, in vivo and in silico cell classes in mouse primary visual cortex" was published on Nature Communications. 关于" 之江实验室发表研究成果 用计算模型理解大脑视觉机制"的新闻被腾讯网，中国新闻网，杭州网等报道. The news about "Matching Form and Function of Brain Cell Types " was reported on April 23, 2023, and reprinted by a number of scientific outlets including ScienceDaily, EurekAlert, etc.
My research on "Cellular Classes in the Human Brain Revealed In Vivo by Heartbeat-Related Modulation of the Extracellular Action Potential Waveform" was published on Cell Reports. This project was additionally featured in a news article "what our heartbeats reveal about our brains" on March 10, 2020 in the Allen Institute News&Press and another news article "Scientists categorize neurons by the way the brain jiggles during a heartbeat" in ScienceDaily, EurekAlert, Neuroscience News, and UPI. One Chinese news related to this project about " 心脑相连？艾伦研究所发现心跳时，大脑会抖动，首次揭示如何在人类大脑中实现适度跨越？” was published by the Brainnews.
My Postdoctoral research on "Synaptic Mechanisms of Memory Consolidation during Sleep Slow Oscillations" was published on the Journal of Neuroscience. This project was additionally featured in a news article titled "how the brain consolidates memory during deep sleep" on Apr 14, 2016 by UCR News, and has also been reprinted by a number of scientific outlets including ScienceDaily, EurekAlert, American Sleep Association, HealthCanal, MedicalXPress, Healthandtreatment.top, Science Bulletin, Science Beta,eScience News ,The Statesman, Weekly Hot News, Deccan Chronicle, Sleep Review, Latest News, Medical News Today ，Science Codex , Highlandernews, etc.
My research on "How the brain consolidates memory during deep sleep" was invited to publish in a layman's language on Nov 8, 2016 at Atlas of Science.
My PhD study about "Unification of neuronal spikes, seizures, and spreading depression" was published on the Journal of Neuroscience. This project was additionally featured in a news article titled "link seen between seizures and migraines in the brain" on Oct 30, 2014 by PSU News , and has been reprinted by many scientific news sites including NSF, ScienceDaily, EurekAlert, Science World Report, MedicalXPress，Neuroscience News，Toronto Telegraph etc.
Education
Aug. 2007-- May. 2013, The Pennsylvania State University
§ Ph.D. in Engineering Science (Neural Engineering Specialization)；Advisor: Dr. Steven Schiff
§ Ph.D. Minor in Computational Science (programming and algorithms）
Sep. 2005-- June. 2007, Zhejiang University, Hangzhou, China
§ M.S., Dept. of Biomedical Engineering
Sep. 2000--June. 2005, Zhejiang University, Hangzhou, China
§ B.S., Dept. of Biomedical Engineering
Work Experience
Dec 2020 - Now, Principal Investigator, Zhejiang Lab, Hangzhou, China
Dec 2017 - Dec 2020, Scientist, Allen Institute for Brain Science, Seattle, WA, USA
Apr 2016- Dec 2017, Postdoc, University of California, San Diego, CA, USA
Nov 2013- March 2016, Postdoc, University of California, Riverside, CA, USA
May 2013- Nov 2013, Research Scholar, Penn State Center for Neural Engineering, State College, PA,USA
Selected Publications
Yina Wei, Anirban Nandi, Xiaoxuan Jia, Thomas Chartrand, Joshua H. Siegle, Daniel Denman, Soo Yeun Lee, Anatoly Buchin, Werner Van Geit, Clayton P. Mosher, Shawn Olsen, Costas A. Anastassiou, Associations between in vitro, in vivo and in silico cell classes in mouse primary visual cortex, Nature Communications, 2023, 14(1),2344
Clayton P Mosher#, Yina Wei#, Jan Kamiński, Anirban Nandi, Adam N Mamelak, Costas A Anastassiou, Ueli Rutishauser. Cellular classes in the human brain revealed in vivo by heartbeat-related modulation of the extracellular action potential waveform, Cell Reports, 2020, 30(10): 3536-3551.e6 (# designates equal contribution) (Cover Article)
Yina Wei, Giri P Krishnan, Lisa Marshall, Thomas Martinetz, Maxim Bazhenov, Stimulation augments spike sequence replay and memory consolidation during slow-wave sleep, Journal of Neuroscience, 2020, 40(4), 811–824 (Featured Article)
Yina Wei#, Giri P Krishnan#, Maxim Komarov, Maxim Bazhenov, Differential roles of sleep spindles and sleep slow oscillations in memory consolidation, PLoS Computational Biology, 2018, 14(7): e1006322 (# designates equal contribution)
Yina Wei, Giri P Krishnan, Maxim Bazhenov, Synaptic mechanisms of memory consolidation during sleep slow oscillations. Journal of Neuroscience, 2016, 36(15): 4231-4247.
Yina Wei, Ghanim Ullah, Steven J. Schiff, Unification of neuronal spikes, seizures, and spreading depression. Journal of Neuroscience, 2014, 34 (35): 11733-43.
Presentations
Wei Y, Denman DJ, Kim I, Kremen V, Change SY, Jo HJ, Koch C, Worrell, Anastassiou, In vivo cortical circuit characterization in a large-animal model through massively parallel extracellular Neuropixels recordings, Society for Neuroscience. 2019 Oct. Chicago, IL, USA
Mosher C#, Wei Y#, Kaminski J, Nandi A, Mamelak A, Anastassiou CA, Rutishauser U, Cellular classes in the human brain revealed in vivo by heartbeat-related modulation of the extracellular action potential waveform, Society for Neuroscience. 2019 Oct. Chicago, IL, USA
Wei Y, Jia X, NanDi A, Anastassiou C, Dai K, Olsen S, Anastassiou C. Comparison between model and experiments: features of the extracellular spike waveform vary with different cell types, Society for Neuroscience. 2018 Nov. San Diego, CA, USA
Mosher C, Wei Y, Kaminski J, Young M, Rudebeck P, Anastassiou C, Rutishauser U. Features of the extracellular action potential vary with the cardiac cycle: toward in vivo classification of cells in the human and macaque brain. Society for Neuroscience. 2018 Nov. San Diego, CA, USA
Wei Y, Nandi A, Anastassiou C. Development of realistic single-neuron models of mouse V1 capturing in vitro and in vivo properties. The Annual computational neuroscience meeting: CNS*2018, Seattle, USA.
Wei Y, Krishnan GP, Komarov M, Bazhenov M. Synaptic mechanisms of memory consolidation during NREM sleep. The 24th Annual Joint Symposium on Neural Computation, 2017 May. University of California, San Diego, CA, USA
Wei Y, Krishnan GP, Bazhenov M. Synaptic mechanisms of memory consolidation during NREM sleep. The 46th Society for Neuroscience. 2016 Nov. San Diego, CA, USA
Wei Y, Krishnan GP, Bazhenov M. Effect of learning cues on memory consolidation during sleep depends on the phase of sleep slow oscillation. The 46th Society for Neuroscience. 2016 Nov. San Diego, CA, USA
Wei Y, Krishnan GP, Bazhenov M. Memory consolidation during sleep slow oscillations. The 22nd Annual Joint Symposium on Neural Computation. 2015 May. University of Southern California, Los Angeles, CA, USA
Wei Y, Krishnan GP, Bazhenov M. Memory consolidation during sleep slow oscillations, The 2nd Annual CEPCEB Postdoc Symposium. 2015 June. University of California, Riverside, CA, USA
Wei Y, Krishnan GP, Bazhenov M. Memory consolidation during sleep slow oscillations. The 44th Society for Neuroscience. 2014 Nov. Washington DC, USA
Wei Y, Krishnan GP, Bazhenov M. Neuronal plasticity during sleep slow wave oscillations. The 23rd Annual Computational Neuroscience Meeting: CNS*2014. 2014 July. Québec City, Canada.
Wei Y, Ullah G, Ingram J, Schiff SJ. Oxygen dynamics during in vitro seizures. The 21st Annual Computational Neuroscience Meeting: CNS*2012. 2012 July. Decatur, GA, USA.
Wei Y, Ullah G, Parekh R, Gluckman BJ, Schiff SJ. Untangling the interplay among hippocampal neurons. The 40th Society for Neuroscience, 2010 Nov., San Diego, CA, USA
Wei Y, Ullah G, Gluckman BJ, Schiff SJ. Tracking of neuronal dynamics based on a hippocampal network model. The 39th Society for Neuroscience, 2009 Nov., Chicago, IL, USA
Invited talks
Comparison between model and experiments: features of the extracellular spike waveform vary with different cell types, in the symposium “Symposium on Neural Computation and Beyond (SYNCB 2018)”, Beijing Normal University, Beijing, China, Dec 21-24, 2018]
Differential roles of sleep spindles and sleep slow oscillations in memory consolidation, in the workshop “Dynamics of Rhythm Generation”, The 27th Annual computational neuroscience meeting: CNS*2018, July 13-18, Seattle, USA.
The role of oxygen on the dynamics of seizure and spreading depression, in the workshop “Mathematical Modeling of Cortical Spreading Depression (SD) and Related Phenomena,” University of Minnesota, Feb12-16, 2018
The role of sleep on memory consolidation, Tianjin University of Technology and Education, Tianjin, China, Apr 25, 2017
Professional services
The reviewer of Nature Communications
The reviewer of Cell Reports
The reviewer of Journal of Neurophysiology
The reviewer of International Journal of Neural Systems
The reviewer of PLOS ONE
The reviewer of Journal of Computational Neuroscience
The reviewer of World Journal of Neuroscience
The reviewer of International Journal of Modern Physics B
The reviewer of PLOS Computational Biology
The reviewer of Frontiers in Computational Neuroscience
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