Announcements

SIAM UQ 2018
I'll be attending the SIAM Conference on Uncertainty Quantification 2018. You can catch my brief review of methods for causal effect quantification on Thursday afternoon. Abstract below.Researchers in applied statistics have developed a number of methods for the quantification of treatment effect size and variability from observational (i.e., nonexperimental) data. However, the these methods suffer two major limitations. First, the proposed models may suffer from misspecifications as a result of marginalizing (unobserved latent confounders) and conditioning (nonrandom selection effects) relative to the datagenerating model. Second, the data collected is often censored or incomplete. As a result of these uncertainties, inference methods associated with such models are inefficient at best and totally incorrect at worst ...
Posted Apr 9, 2018, 6:45 AM by Clay Thompson

Academia vs Industry
From Dan Simpson:
But I’m an academic statistician. And our key feature, as a people, is that we loudly and publicly dislike each other’s work. Even the stuff we agree with. Why? Because people with our skills who also have impulse control tend to work for more money in the private sector.
Posted Jan 2, 2018, 7:23 AM by Clay Thompson

Text highlighting during git commit message edit using vim
When writing a git commit message, it is good practice to follow some rules regarding formatting. If you are a rightthinking person and use vim as your editor, this is made very easyvim will highlight the text in different colors in accordance with these rules. Unfortunately, this was not working for me. After reading through the depths of the internet, the solution ended up being almost mindlessly simple. You just need to set the default editor (or, more generally, the editor that git is using) properly.
Posted Nov 30, 2017, 5:22 PM by Clay Thompson
Basic InformationWilliam Clayton Thompson ('Clay')
Senior Research Statistician Developer Multivariable Models R&D SAS Institute Cary, NC, USA
Research InterestsMathematical/computational modeling of physiological processes Model calibration and validation for largescale systems models Modular coding, algorithm design, and data structures for largescale models Computational tools for reproducible research Uncertainty quantification, variability modeling, rigorous model comparison Mathematical and statistical aspects of inverse problems; statistical inference Practical applications of functional analysis and measure theory Scientific and mathematical methods to improve public policy
Recent Publications
W. Clayton Thompson, Yingjiang Zhou, Saswata Talukdar, and C.J. Musante, PF05231023, a longacting FGF21 analogue, decreases body weight by reduction of food intake in nonhuman primates, JPKPD 43 (2016) 411425. PMID 27405817
J. Selimkhanov, W.Clayton Thompson, T.S. Maurer, and C.J. Musante, Evaluation of a mathematical model of rat body weight regulation in application to caloric restriction and drug treatment studies, PLoS ONE 11 (2016) e0155674.
Recent Presentations 