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Welcome to Vashisth Research Group webpage at UNH Chemical Engineering!

We are a new theoretical and computational biophysics group seeking to understand the structure, dynamics, and function of biomolecules via molecular modeling and simulation techniques for technological and therapeutic applications. Motivated undergraduate and graduate students as well as postdoctoral researchers are highly encouraged to contact Dr. Vashisth for more information.

*Note: We have current openings for graduate students for Fall-2018*

*Note: We have current openings for postdoctoral researchers for Fall-2018*

News

2018

  • Sep17: A manuscript on simulation methods for resolving H/D exchange in proteins accepted for publication in Journal of Physical Chemistry (see Publications)
  • Sep15: Harish and a collaborative NH team awarded an NSF grant for creating the New Hampshire Center for Multiscale Modeling and Manufacturing of Biomaterials: NH-BioMade (info) (UNHToday) (NSF-news) (NH-EPSCoR) (Dartmouth-news) (NHBR) (Telegraph)
  • Aug22: Harish awarded a pilot research project grant from the NIH Center for Integrated Biomedical and Bioengineering Research (CIBBR) at UNH (info)
  • Aug19-23: Mohammadjavad, Lev, Yong, and Ryan presented posters/talks at Fall 2018 ACS Annual Meeting, Boston, MA
  • Aug15: Harish presented work on biomimetic water channels at Gordon Research Conference on Membranes, New London, NH (info)
  • Aug10: Harish and collaborators awarded an NSF grant for acquisition of a high-field NMR spectrometer to study biomolecular structure and dynamics (info)
  • Jul15-20: Harish presented group's research work and an NSF-supported workshop on enhanced sampling simulation methods at the triennial FOMMS-2018 meeting (info)
  • Jun25-27: Harish presented work on biomimetic water channels at a Royal Society of Chemistry meeting on Artificial Water Channels in Glasgow, UK (info)
  • Jun26-28: Lev and Mohammadjavad present posters at the 78th Physical Electronics Conference (PEC-2018) in Durham, NH (info)
  • May18: Michelle Chen, Evan Redfearn, and Michael Beck join lab as summer undergraduate/REU researchers
  • May9: A manuscript on artificial water-channel biomimetic membranes accepted for publication in Nature Communications (see Publications)
  • May8: Mohammadjavad Mohammadi wins the best graduate student poster award at 2018 UNH Bioengineering Symposium
  • May8: Lev, Mohammadjavad, Yong, and Altai present posters at 2018 UNH Bioengineering Symposium (info)
  • April19: Yong Liu successfully finishes his PhD Candidacy exam--Congratulations!
  • Apr18: Altai Perry, an undergraduate researcher in our lab, presents research at the Undergraduate Research Conference (URC) at UNH (info)
  • Apr17: Harish awarded NSF REU funding to provide research experiences to undergraduate students during Summer-2018
  • Apr15: Mohammadjavad presents research at Northeast Student Chemistry Research Conference (NSCRC), Northeastern University (info)
  • Apr13: A manuscript on interatomic potentials for biomimetic membranes accepted for publication in Faraday Discuss. (see Publications)
  • Apr9-10: Mohammadjavad, Lev, and Yong, current graduate students in the group present research at annual UNH Graduate Research Conference (info)
  • Feb20: A manuscript on the role of differential protein dynamics in inhibitor binding accepted for publication in J. Am. Chem. Soc. (see Publications)
  • Jan5: Harish presented a seminar talk in the Department of Biosciences and Bioengineering at the Indian Institute of Technology (IIT), Bombay, India (info)

2017

  • Dec18-20: Harish presented an invited talk at a conference on complex fluids, CompFlu, held in Indian Institute of Technology (IIT), Madras, India (info)
  • Dec14 : Mohammadjavad attends a workshop on Anton supercomputer at Pittsburgh Supercomputing Center
  • Dec7-10: Harish presented an invited talk at Indo/US meeting on RARE event simulations held in Agra, India (info)
  • Nov 30: Our computational grant on Anton highlighted in "Tech Tidbits" of New Hampshire Business Review (info)
  • Nov 26: Hossein's internship experience at UCSD and computational work highlighted in a UNH news story (UNH Today)
  • Nov 14: Harish gives an invited public presentation on 3D visualization alongside speakers on 3D gaming and 3D building design in a Portsmouth Music Hall event on The Art of 3D Modeling (info)
  • Nov 1: Yong Liu joins our group as a new PhD student--Welcome!
  • Oct 31: Harish awarded a second computational grant on Anton supercomputer for large-scale simulation studies of signaling receptors (info)
  • Oct29-Nov3: Harish and graduate students (Mohammadjavad and Hossein) attended and presented talks/posters at the 2017 AIChE meeting in Minneapolis, MN
  • Oct25: Harish presented a seminar talk in the Trout Group@MIT Chemical Engineering
  • Oct24: Congratulations to Hossein Mohammadiarani for successfully defending his PhD thesis on studies of Signaling and Regulatory Proteins!
  • Oct13: Harish presented a seminar talk at the Penn Institute for Computational Sciences (PICS) of the University of Pennsylvania, Philadelphia, PA
  • Oct4: Mohammadjavad's first manuscript on ligand diffusion in enzymes published in J. Phys. Chem. B (see Publications)
  • Oct3: Harish presented a seminar talk in the Department of Chemical Engineering at Oklahoma State University, Stillwater, OK
  • Sep20-23: Vince Shaw, a collaborating PhD student from the Neubig Lab at Michigan State University, visited us and participated in discussions on protein dynamics and drug discovery
  • Sep15: Harish presented a seminar talk in the Department of Chemical and Biomolecular Engineering at Ohio University, Athens, OH
  • Sep6: Hossein Mohammadiarani, a PhD student in our lab, finished an NSF-sponsored Internship in data science with Prof. Ruben Abagyan in Skaggs School of Pharmacy at UCSD, La Jolla, CA
  • Aug20-24: Harish presented two talks and a poster at ACS Fall Meeting in DC (info)
  • Jun26: Two school teachers start summer work in our lab under NSF funded program Research Experience for Teachers in Engineering (RETE)
  • Jun23: Rhiannon Jacobs and Lev Levintov--first-year PhD students in our lab--successfully completed PhD Qualifying exam--Congratulations!
  • Jun11-16: Harish attended and presented work on protein-protein interactions at the Gordon Conference on Computational Aspects of Biomolecular NMR (info)
  • May22: Michael Beck and Altai Perry, NSF supported REU undergraduate researchers, start summer work in our lab
  • May13: Harish and Rhiannon present the third NSF-sponsored workshop on Visuospatial Thinking at the Spring conference of NH Science Teachers Association (NHSTA) at Coe-Brown Academy
  • May12: Harish and a team of UNH collaborators from College of Life Sciences will be awarded a Pilot Research Partnership grant via UNH's CoRE Initiative to study photoreceptor signaling (info)
  • May12: Congratulations to Ryan Barden for successfully defending his MS thesis on studies of biomimetic membranes!
  • May10: Rhiannon Jacobs wins the best graduate student poster award at 2017 UNH Bioengineering Symposium
  • May10: Hossein, Mohammadjavad, Rhiannon, and Ryan present posters at 2017 UNH Bioengineering Symposium (info)
  • Apr20: Michael Beck, an undergraduate researcher in our lab, presents a poster on RNA/protein interactions at the Undergraduate Research Conference (URC) at UNH (info)
  • Apr13 : Mohammadjavad presents research at ISPE's Boston Area Chapter Meeting (info)
  • Apr10-11 : Ryan, Rhiannon, Mohammadjavad, and Hossein present research at annual UNH Graduate Research Conference (info)
  • Apr9 : A new manuscript on kinetics of ligand binding accepted for publication in Curr. Top. Med. Chem. (see Publications)
  • Apr8 : Mohammadjavad presents research at Northeast Student Chemistry Research Conference, Cambridge, MA (info)
  • Mar31 : Harish awarded REU funding via NSF CAREER grant to support two undergraduate students during Summer-2017
  • Mar2-3, 13-14, 22-24 : Harish serves as a panelist on three NSF grant review panels (ENG and MPS Directorates) in DC
  • Feb14 : Hossein presents his research on dynamics of RGS proteins at 2017 Biophysical Society Meeting in New Orleans, LA (abstract)
  • Feb1 : Michael Beck is working again as an undergraduate researcher in our lab this Spring
  • Jan24 : Harish serves as a panelist on an NSF grant review panel in DC
  • Jan7 : Hossein's paper on structural models of insulin-mimetic peptides accepted for publication in J. Comput. Chem. (see Publications)
  • Jan1 : We welcome Lev Levintov as a new PhD student in our group!
  • Jan1 : Harish awarded an XSEDE computational research grant for studying protein and RNA based drug discovery (info)

2016

  • Dec 9 : Harish serves again on the undergraduate Goldwater Scholarship selection committee
  • Nov30 : Hossein attends a workshop on Anton supercomputer at Pittsburgh Supercomputing Center
  • Nov17 : Harish attended and presented a talk on Rhiannon's RNA work at the AIChE Annual Meeting in San Francisco, CA
  • Nov1 : Harish awarded a computational grant on Anton supercomputer for large-scale simulation studies of the insulin receptor (UNH Today)
  • Oct31 : Rhiannon presents the second NSF-sponsored workshop on Visuospatial Thinking at the Fall conference of NH Science Teachers Association, NHSTA
  • Oct27 : Harish presents a seminar talk in College of Pharmacy at the University of New England
  • Oct14 : Hossein presents a poster on drug discovery for RGS proteins at the 2016 NESS Symposium of University of Connecticut
  • Oct4 : Mohammadjavad successfully finishes his PhD Candidacy exam--Congratulations!
  • Sep23 : Harish receives AIChE Honor Roll Award a second time for services as the advisor of the UNH AIChE Student Chapter from 2013-2016
  • Sep9 : Harish presents a seminar talk in Dept. of Chemistry & Biochemistry at the University of Delaware
  • Aug29 : Sri Padamati and Michael Beck are undergraduate researchers in our lab this Fall
  • Aug3-4: Rhiannon awarded a travel fellowship to participate in an NSF sponsored Visualization workshop held jointly at Purdue University and the University of Illinois at Urbana-Champaign (info)
  • Jul25 : Harish presents a seminar talk in Dept. of Chemical Engineering at the Indian Institute of Technology (IIT), Roorkee (India)
  • Jun13 : Kate Verfaillie, a pre-service teacher, starts summer work in our lab under NSF program Research Experience for Teachers in Engineering (RETE)
  • Jun7 : Hossein's first paper on structural models of receptor transmembrane domains accepted for publication in Front. Endocrinol. (see Publications)
  • May23: Michael Beck (undergraduate researcher) and Mohammadjavad Mohammadi (graduate student) start summer work in our lab
  • May21: Congratulations to Rhiannon Jacobs and Ryan Barden on graduation!
  • May10: Rhiannon Jacobs successfully finishes work as a McNair Scholar and will be continuing in our group as a graduate student
  • May3: Our collaborator Prof. Rick Neubig (Chairman, Pharmacology&Toxicology, Michigan State University) presents 2016 Sam Smith Lectureship in Molecular Medicine at UNH (info)
  • Apr29: Harish presents work on RGS proteins at "Sailing the Protein Seas" Symposium of Brown University (info)
  • Apr22: UNH ChemE Car team and AIChE student chapter members advised by Harish attend regional AIChE meeting at UMASS, Amherst (info)
  • Apr20: Rhiannon Jacobs and Ryan Barden present posters at the Undergraduate Research Conference (URC) at UNH (info)
  • Apr2: Harish and Rhiannon Jacobs present the first NSF-sponsored workshop on Visuospatial Thinking at the Spring conference of NH Science Teachers Association, NHSTA (info)
  • Mar29: Harish serves as a panelist again on an NSF review panel (MPS Directorate) in DC
  • Mar24: Harish presents a talk at the first UNH Research Computing Day (info)
  • Mar22: Harish attends a comprehensive one day NIH-INBRE grant writing seminar at Dartmouth College
  • Mar16: Harish presents a talk at ACS Spring Meeting symposium "Adventures in Simulating Biomolecules" organized in honor of Prof. Charles L. Brooks III's 60th birthday (info)
  • Mar15: UNH Chem-E-Car team advised by Harish awarded Hamel Center's Research Presentation Grant for regional AIChE meeting at UMASS, Amherst (info)
  • Mar10: Rhiannon presents her research on RNA structure & Dynamics at McNair Conference at the University of Maryland (info)
  • Feb28: Hossein presents his research on membrane-peptide folding at 2016 Biophysical Society Meeting in Los Angeles, CA (conference abstract)
  • Feb8: Harish serves as a panelist on an NSF grant review panel (ENG Directorate) in DC
  • Jan22: Harish wins NSF CAREER Award to study RNA dynamics and interfacial interactions (info) (UNH Today) (UNH ChemEng) (Drexel CBE) (NSF News) (NSF Tumblr)
  • Jan18: Ryan Barden (Senior, Chemical Eng.) and Cape Carson (Senior, MCBS) join lab as new undergraduate researchers--Welcome!
  • Jan15: Harish serves as a reviewer for NSF Graduate Research Fellowship (GRFP) program

2015

  • Nov19 : Congratulations to Tyler Mulligan for successfully defending his MS thesis on studies of nucleoprotein complexes!
  • Nov8 : Harish attended and presented a talk at the AIChE Annual Meeting in Salt Lake City, UT
  • Oct10 : Hossein presents a poster at the NESS Symposium of University of Connecticut
  • Oct2 : Hossein, Tyler, and Rhiannon present posters at the 2015 UNH Bioengineering Symposium (info)
  • Oct1 : Harish awarded AIChE Honor Roll Award for services as the advisor of the UNH AIChE Student Chapter
  • Sep 15:Harish presented a seminar talk in Department of Chemistry at UNH (info)
  • Aug20: Harish presented a talk on peptide folding simulations at the American Chemical Society (ACS) meeting in Boston
  • Aug10: Harish and Rick Neubig awarded NSF grant to study small-molecule inhibitors of RGS proteins (info)
  • Aug5 : Rhiannon, Brunno, and Jay finish their summer work and presented research at various meetings, conferences, and symposia
  • Jul16 : Harish presented a poster at the sixth triennial FOMMS conference in Welches, OR (info)
  • Jun29 : Jay Derick starts simulation work on enzymes in our lab under NSF program Research Experience for Teachers in Engineering (RETE)
  • Jun1 : Two undergraduates, Rhiannon Jacobs (a McNair Scholar) and Brunno Carvalho Rocha (via Brazil Scientific Mobility Program), start summer work in our lab
  • Apr22 : Rhiannon and Greg present posters at the Undergraduate Research Conference (URC) at UNH (info)
  • Apr10 : Harish presented a seminar talk in Pharmacology&Toxicology at Michigan State University (info)
  • Apr9 : Rhiannon awarded 2015 McNair Summer Fellowship to work on understanding RNA dynamics
  • Apr1 : Hossein awarded Summer Teaching Assistant Fellowship (STAF) from UNH Graduate School
  • Mar28: Hossein and Harish presented research at the American Society for Biochemistry and Molecular Biology (ASBMB) meeting in Boston
  • Mar19: Harish awarded Summer Faculty Fellowship from UNH Graduate School for peptide folding work
  • Mar8 : Rhiannon presented a poster at the AIChE regional meeting (at MIT/Northeastern University) in Boston
  • Mar6 : Rhiannon and the UNH ChemE Car team advised by Harish awarded Hamel Center's Research Presentation Grants for regional AIChE meeting in Boston
  • Feb23: Harish presented a seminar talk in Molecular, Cellular, and Biomedical Sciences (MCBS) at UNH (info)
  • Feb16: Harish is now serving on the Editorial Board of journal Frontiers in Endocrinology
  • Feb11: Paper on computational studies of the insulin receptor family published in Membranes (see publications)

2014

  • Harish serves again on the undergraduate Goldwater Scholarship selection committee
  • Rhiannon accepted to participate in McNair Scholars Program
  • Rhiannon wins the best undergraduate poster award at the 2014 UNH Bioengineering Symposium
  • Hossein, Tyler, Rhiannon presented posters at the 2014 UNH Bioengineering Symposium
  • Paper on a new insulin/insulin-receptor complex published in Membranes (see publications)
  • Daniel Brandow joins our group as an undergraduate researcher
  • Lilia Vinskus, Lily Zemelko, and Noah Raz, seniors from the Pinkerton Academy, join our group
  • Harish is serving as the Associate Guest Editor for journal Frontiers in Biotechnology and Bioengineering (info)
  • Harish awarded funds by the Provost's office to organize the first UNH Bioengineering Symposium on Oct 10, 2014 (info)
  • Greg Samuel finished summer work in lab under NSF program Research Experience for Teachers in Engineering (RETE)
  • Harish attends NSF Day workshop at Cold Spring Harbor, NY
  • Rhiannon presented posters at the AIChE regional meeting at UCONN and UNH Undergraduate Research Conference
  • Rhiannon and the UNH ChemE Car team (advised by Harish) receive Research Presentation Grants for regional AIChE meeting at UCONN
  • Harish presented a seminar talk in Chemical Engineering at the University of Rhode Island
  • Paper on collective variable methods published in Chemical Reviews (see publications)
  • Welcome New Students: Hossein and Tyler (graduate students), Rhiannon and Lindsay (undergraduate students)
  • 2013
  • Harish elected as UNH Research&Engagement Academy Faculty Scholar (info)
  • Harish serves on the undergraduate Goldwater Scholarship selection committee
  • Paper on RGS proteins published in ACS Chemical Biology (see publications)
  • Harish awarded an XSEDE startup computational grant