Microbial Morphogenesis and Growth
Our lab is interested in how bacteria acquire, maintain, and modify their shapes during growth. Furthermore, we try to elucidate how bacteria coordinate general physiology with shape. For example, how do bacteria 'know' in a certain nutrient environment at what rate they have to expand their cell envelope to make space for intracellular protein, DNA, etc.? How do they know when to divide, and when to undergo a transition into dormancy? Our lab addresses these questions with combined techniques from physics and microbiology. In particular, we are using state-of-the art fluorescence microscopy, quantitative image analysis, and modeling to decipher how bacteria organize in space and time.
Since January 2014 we have a physical lab space at the Institut Pasteur in Paris. The so-called G5 (group 5 années) lab will be funded by Institut Pasteur and the LabEx 'Integrative Biology of Infectious Diseases' (IBEID) and is situated in the brand-new building 'Francois Jacob' on the Pasteur campus.