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Dr Graham Heap

Dr Graham Heap is a post-doctoral researcher working within the van Heel group. His research interests include the genetics of complex diseases and assigning function to genetic variants that are associated with disease. This involves high-throughput genotyping, expression analysis (microarrays) and high-throughput sequencing using both laboratory and bioinformatic approaches.  

His key publications include:

Heap GA, Healy BC, Hunt KA, Downes K, Yang JH, Bockett N, Franke L, Dubois PC, Clayton DG, Todd JA, van Heel DA, Plagnol V. Genome-wide analysis of allelic expression imbalance in human primary cells by high throughput transcriptome resequencing. Human Molecular Genetics. Hum Mol Genet. 2010 Jan 1 19(1):122-3

Heap GA, van Heel DA. Genetics and pathogenesis of coeliac disease. Semin Immunol. 2009 Dec;21(6):346-54.

Heap GA, van Heel DA. The genetics of chronic inflammatory diseases. Hum Mol Genet. 2009 Apr 15;18(R1):R101-6. 

Heap GA, Trynka G, Jansen RC, Bruinenberg M, Swertz MA, Dinesen LC, Hunt KA, Wijmenga C, van heel DA, Franke L. Complex nature of SNP genotype effects on gene expression in primary human leucocytes. BMC Med Genomics. 2009 Jan 7;2:1.

A complete list of all publications can be found here