Welcome to the Neurobiology and Developmental Genetics Laboratory. We are located in Biotechnology Centre Building at University of Delhi (South Campus), New Delhi, India. 

Our research interest is primarily focused on the genetic, cellular and molecular basis of human neurodegenerative disorders and its association with aging process. Human neurodegenerative disorders are devastating illnesses characterized by progressive loss of neurons in specific areas of brain causing various neurological complications leading to death. Some of these disorders are Parkinson's disease, Alzheimer's disease, Spinal and bulbar Muscular atrophy (SBMA), Dentatorubral pallidoluysian atrophy, Huntington’s disease (HD) and several kinds of the Spinocerebellar ataxias etc. In addition, we are also interested to study the developmental relevance of the multiple globins and stress genes. 

We extensively utilise Drosophila melanogaster as model organism which provides a powerful array of genetic, molecular, and cellular approaches. Furthermore, availability of Drosophila disease models offers a unique opportunity to study the insights of human neurodegenerative disorders. 

Our recent findings demonstrate that targeted over-expression of dMyc (a homologue of human cMyc proto-oncogene) could potentially suppresses human poly(Q) induced neurodegeneration and cellular toxicity in Drosophila disease models. These novel finding could potentially help in designing novel therapeutic approach to suppress some fatal human neurodegenerative disorders.

“The Hindu”- India’s National Newspaper Reports Our Research Findings

 URL: http://www.thehindu.com/sci-tech/health/cancer-drugs-can-stop-progression-of-alzheimers-parkinsons/article8513695.ece