Located in the Kaul Human Genetics Building, the Transgenic & Genetically Engineered Models (TGEMs) Core Facility provides a variety of services to the UAB community and partner institutions.  Our services predominantly include the production of mouse models using gene targeting and DNA and ES cell injection methods.  Our most recent service is in creating gene knockouts using the TALEN and CRISPR/Cas9 nucleases in mice, rats and zebrafish.