Speech is often effortless and relatively fast. When we talk, we say on average two to three words per second, out of an active vocabulary of tens of thousands of words. There is an infinite number of word combinations, yet we say words in the proper order with the right sounds. How do we successfully select and order words during fluent speech? Why does speech deteriorate because of brain damage? Language is essential to human interaction, yet little is known about how it happens in both the brain and the mind. We use a combination of behavioral, neuropsychological, and neuroscience methods to answer these questions.