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RNN-based predictive automatic focusing system for long term live embryo development imaging

posted Dec 14, 2017, 11:21 AM by Paul, Hsieh-Fu Tsai
unlike conventional live cell time lapse imaging system, which locks focuses by finding a interface usually a air/glass or glass/water interface to compensate for thermal focus drift.

live biological samples with large volume often have oscillation of spontaneous movement that cannot be compensate even through deep anethesia.
A RNN based predicitive focusing system maybe able to compensate for the moving of the sample and adjust focus to keep locked on interested region