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Publications

2014

(4) Troutman, J.M., Sharma, S., Erickson, K.M., Martinez, C.D. Functional Identification of a galactosyltransferase critical to Bacteroides fragilis Capsular Polysaccharide A biosynthesis. Carbohydrate Research (Accepted).

2013

(3) Mostafavi, A.Z., Lujan, D.K., Erickson, K.M., Martinez, C.D., Troutman J.M. Fluorescent probes for investigation of isoprenoid configuration and size discrimination by bactoprenol-utilizing enzymes. Bioorg Med Chem, 21, 5428-35.

(2) Mostafavi, A.Z., Troutman J.M.  Biosynthetic assembly of the Bacteroides fragilis capsular polysaccharide A precursor bactoprenyl diphosphate-linked acetamido-4-amino-6-deoxy-galactopyranose. Biochemistry, 52, 1939-1949. (Biochemistry webpage highlight article)


2012

(1) Lujan, D.K., Stanziale, J.A., Mostafavi, A.Z., Sharma, S. Troutman, J.M. Chemoenzymatic synthesis of an isoprenoid phosphate tool for the analysis of complex bacterial oligosaccharide biosynthesis. Carbohydrate Research 359, 44-53. (Highlighted in virtual special issue on carbohydrate synthesis 2013.)





Graduate and Post-Doc Publications.


(12) Subramanian, T., Pais, J.E., Liu, S., Troutman J.M., Subramanian, K.L., Fierke, C.A., Spielmann, H.P. (2012Farnesyl diphosphate analogues with aryl moieties are efficient alternative substrates for protein farnesyltransferase. Biochemistry 51, 8307-8319.

(11) Morrison, J.P., Troutman, J.M., Imperiali B. (2010Development of a multicomponent kinetic assay of the early enzymes in the Campylobacter jejuni N-linked glycosylation pathway. Bioorg Med Chem 18, 8167-71.

(10) Adams, V.R., Deremer, D.L., Stevich, B., Mattingly, C.A., Gallt, B., Subramanian, T., Troutman, J.M., Spielmann, H.P. (2010Anticancer activity of novel unnatural synthetic isoprenoids. Anticancer Research 30, 2505-12.


(8) Subramanian, T., Liu, S., Troutman, J.M., Andres, D.A., Spielmann H.P. (2008Protein farnesyltransferase catalyzed isoprenoid transfer to peptide depends on lipid size and shape not hydrophobicity. Chembiochem 9, 2872-82.


(6) Troutman, J. M., Andres, D. A., and Spielmann, H. P. (2007Protein farnesyl transferase target selectivity is dependent upon peptide stimulated product release. Biochemistry 46, 11299-309.

(5) Roberts, M. J., Troutman, J. M., Chehade, K. A., Cha, H. C., Kao, J. P., Huang, X., Zhan, C. G., Peterson, Y. K., Subramanian, T., Kamalakkannan, S., Andres, D. A., and Spielmann, H. P. (2006Hydrophilic Anilinogeranyl Diphosphate Prenyl Analogues Are Ras Function Inhibitors. Biochemistry 45, 15862-15872.

(4) Troutman, J. M., Roberts, M. J., Andres, D. A., and Spielmann, H. P. (2005Tools to analyze protein farnesylation in cells. Bioconjug Chem 16, 1209-17.

(3) Subramanian, T., Wang, Z., Troutman, J. M., Andres, D. A., and Spielmann, H. P. (2005Directed library of anilinogeranyl analogues of farnesyl diphosphate via mixed solid- and solution-phase synthesis. Org Lett 7, 2109-12.

(2) Troutman, J. M., Chehade, K. A., Kiegiel, K., Andres, D. A., and Spielmann, H. P. (2004Synthesis of acyloxymethyl ester prodrugs of the transferable protein farnesyl transferase substrate farnesyl methylenediphosphonate. Bioorg Med Chem Lett 14, 4979-82.

(1) Kelly, M. A., Chellgren, B. W., Rucker, A. L., Troutman, J. M., Fried, M. G., Miller, A. F., and Creamer, T. P. (2001Host-guest study of left-handed polyproline II helix formation. Biochemistry 40, 14376-83.

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