Liver Support Factors
Country Life Liver Support Factors by Biochem - easily found by googling.
Alanine Aminotransferase or ALT: the enzyme produced within the cells of the liver. The level of ALT abnormality is increased in conditions where cells of the liver have been inflamed or undergone cell death. As the cells are damaged, the ALT leaks into the bloodstream leading to a rise in the serum levels. Any form of hepatic cell damage can result in an elevation in the ALT. The ALT level may or may not correlate with the degree of cell death or inflammation. ALT is the most sensitive marker for liver cell damage.
My German Shepherd Dog, Thunder, was scheduled to get a shot of Imizol (Imidocarb dipropionate) in the hope of knocking out the N. risticii that was killing him. However, Schering-Plough advises vets to use their judgment if they mean to give it to a dog having problems with his lungs, liver or kidneys. A blood test done just before he was to get the shot showed that Thunder's ALT was well over 1200, reason enough to give my vet pause. In an effort to get that number down, she told me to go find Country Life Liver Support Factors by BioChem. Well, I searched and I found it in a local health food store but I didn't really expect much from it, so when I saw the results of his next blood test, it's putting it mildly to say that I was astonished; from her reaction, I think his vet was almost as surprised by how well it worked. After just two weeks on LSF, his ALT had dropped 900 points!
Thunder weighed around 90 pounds and could take an adult human dose. For a dog that weighs less, you could easily adjust the dose as Jackie Carroll, another member of Tick List, did for her 7 year old beagle, Joey, who had an even higher ALT than Thunder.
Joey's ALT maxed out at 2900 at it's high point. According to Jackie, when she gave her Joey LSF his ALT came down rapidly, dropping from 2500 to 1500, then to around 900 on subsequent tests. Once again, a vet was surprised at how quickly LSF worked. Joey weighs around 30 pounds and got 1/2 tablet twice a day.
For long term use, it may be best to pulse LSF since it is mostly herbs which lose their efficacy if given continuously for a long time.
Liver Support Factors: Product Label: Ingredients
This URL links to a commercial site with which I have no affiliation. Nor do I have any affiliation with the manufacturer. Scroll down for a complete list of ingredients. Should this link ever fail, googling the complete name of the product + 100 tabs will lead you right to many other sites that also list the ingredients.
LSF is an alternative to SAMe, S-adenosylmethionine, for support of the liver. Veterinary SAMe is marketed under the brand name Denosyl by Nutrimax Labs which also makes another liver support product for dogs containing SAMe, Denamarin. You can get SAMe at discount drugstores like CostCo or Walmart, I'm told. The generics seem to work just as well as name brands and are cheaper.
Liver Support Factors, however, is not only good but it's inexpensive so you might want to try it first even if you eventually decide to use SAMe.
Since I first added this page, a number of people have told me that LSF works better than anything they've tried. Jackie even told us on Tick List that it worked when SAMe did nothing.
Sue Johnson, the author of Switching to Raw and a breeder of champion English Setters, told me that she gave LSF to her 10 year old bitch, Savannah, when her ALT had begun to climb. In December, it was 260, by January, it was 340. When she retested at the end of February after starting Savannah on LSF, her ALT had gone down to 150. Sue is continuing to give Savannah Liver Support Factors.
Savannah weighs about 48 pounds so Sue chose to give her one tab a day in the mornings, Monday through Friday, and pulse it by holding off on weekends.
Marianna Mayer, a member of K9Nutrition, had this to say about LSF: "The best product I've used. For many years I supplemented with a highly recommended and very expensive human grade milk thistle, and while it did a good job, I took Gil's suggestion and switched to Liver Support Factors. The proof for me was that I was able to watch as each subsequent month my dog's liver screening numbers fell like a stone to normal. Very impressive."
Margaret Park, a member of K9Nutrition and Senior Raw Feeding, agrees with Marianna. "Black Jack (a Standard Poodle) was on Liver Support Factors for years and it kept his liver numbers down. I believe the basic liver problem he had was probably a scarred liver but his numbers kept creeping up before I put him on the Liver Support Factors."