We have moved to a new site.
Post date: Dec 9, 2011 6:57:18 AM
What is the Nobel Prize?
The Nobel Prizes are annual international awards given by Scandinavian Committees in recognition of significant cultural and scientific advancements.The awards were named after the Swedish Chemist Alfred Nobel, the inventor of the dynamite. Nobel included in his will the establishment of the Nobel Prizes, which were funded by the bulk of his estate. Since 1901, the awards have been awarded annually for achievements in five fields namely (1) Physics, (2) Chemistry, (3) Physiology or Medicine, (4) Literature, and (5) Peace. Listing of Nobel Prize Laureates in Medicine and Physiology related to Genetics and Molecular BiologyKossel (1910)
Work on protein including the nucleic substance
Morgan (1933)
Role of chromosomes in heredity
Muller (1946)
Production of mutations by X-ray irradiation
Beadle & Tatum (1958)
Regulation of definite chemical events (one gene:one protein)
Lederberg (1958)
Genetic recombination and the organization of the genetic material in bacteria
Ochoa & Kornberg (1959)
Mechanisms in the biological synthesis of ribonucleic and deoxyribonucleic acid
Crick, Watson & Wilkins (1962)
Molecular structure of nucleic acids and its significance for information transfer in living material
Jacob, Lwoff & Monod (1965)
Genetic control of enzyme and virus synthesis
Holley, Khorana & Nirenberg (1968)
Genetic code and its function in protein synthesis
Delbrück, Hershey & Luria (1969)
The replication mechanism and the genetic structure of viruses
Arber, Nathans & Smith (1978)
Restriction enzymes and their application to problems of molecular genetics
McClintock (1983)
Mobile genetic elements
Tonegawa (1987)
Genetics of Antibody Formation and Diversity
Bishop and Varmus (1989)
Retroviral Oncogenes
Roberts & Sharp (1993)
Split genes
Lewis, Nüsslein-Volhard, Wieschaus (1995)
Genetic control of Early Embryonic Development
Prusiner (1997)
Prions, a new principle of infection
Brenner, Horvitz and Sulston (2002)
Genetic regulation of organ development and programmed cell death
Fire & Mello (2006)
RNA interference
Capechi , Evans & Smithies (2007)
Principles for introducing specific gene modifications in mice by the use of
embryonic stem cells
Blackburn, Greider & Szostak (2008)
Telomeres and Telomerase
Listing of Nobel Prize Laureates in Chemistry with significant contribution to Molecular Biology
Berg, Gilbert, and Sanger (1980)
Biochemistry of Nucleic Acids and Recombinant DNA
Determination of Base Sequences in Nucleic Acids
Klug (1982)
Structure of Biologically Important Nucleic Acid-Protein Complexes
Altman and Cech (1989)
Discovery of the Catalytic Properties of RNA
Mullis and Smith (1993)
Polymerase Chain Reaction
Oligo-nucleotide Site-directed Mutagenesis
Ciechanover, Hershko and Rose (2004)
Ubiquitin-mediated protein degradation
Kornberg (2006)
Molecular Basis of Eukaryotic Transcription
Ramkrishnan, Steitz, and Yonath (2009)
Structure and Function of the Ribosome
1. Increasing awareness among women in their reproductive age on the significance of folic acid supplementation in the prevention of birth defects;
2. Increasing public awareness in saving babies from mental retardation and death through newborn screening; and
3. Lobbying public support for the urgent passage of the Rare Disease Act - an act addressing the needs of patients with rare or orphan disorders.
__________________
References:
The Nobel Prize in Physiology or Medicine, 1901-2000". Nobelprize.org. 9 Dec 2011 http://www.nobelprize.org/nobel_prizes/medicine/articles/lindsten-ringertz-rev/index.html
The Nobel Prize in Chemistry: The Development of Modern Chemistry". Nobelprize.org. 9 Dec 2011 http://www.nobelprize.org/nobel_prizes/chemistry/articles/malmstrom/index.html