ChemPhysChem - FSRS Review

posted May 15, 2016, 11:39 AM by David Wartmann   [ updated May 15, 2016, 11:42 AM ]

Femtosecond stimulated Raman spectroscopy (FSRS) is an ultrafast nonlinear optical technique that provides vibrational structural information with high temporal (sub-50 fs) precision and high spectral (10 cm−1) resolution. Since the first full demonstration of its capabilities ≈ 15 years ago, FSRS has evolved into a mature technique, giving deep insights into chemical and biochemical reaction dynamics that would be inaccessible with any other technique. It is now being routinely applied to virtually all possible photochemical reactions and systems spanning from single molecules in solution to thin films, bulk crystals and macromolecular proteins. This review starts with an historic overview and discusses the theoretical and experimental concepts behind this technology. Emphasis is put on the current state-of-the-art experimental realization and several variations of FSRS that have been developed. The unique capabilities of FSRS are illustrated through a comprehensive presentation of experiments to date followed by prospects.




Chip-based technology enables reliable direct detection of Ebola virus

posted Sep 28, 2015, 5:23 PM by David Wartmann   [ updated Sep 28, 2015, 5:24 PM ]

UC Santa Cruz led a team that included researchers from BYU (Brigham Young University) and UC Berkeley to develop the technology for detecting Ebola.
Read the full article here and find the paper at Scientific Reports.

ACS Conference-talk by R. Mathies

posted Aug 18, 2015, 11:26 PM by David Wartmann   [ updated Aug 18, 2015, 11:28 PM ]

Richard Mathies will give a talk at the annual:

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August 16-20, 2015
Boston, Massachusetts 
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08/19/2015 - 4:35pm 
PHYS 369
Femtosecond stimulated Raman spectroscopy: 
A vibrationally specific probe of reactive nonadiabatic coupling. 


Don't miss it while you are there!

Rapid fabrication of nickel molds for prototyping embossed plastic microfluidic devices

posted Sep 16, 2013, 3:46 AM by Richard Novak

We have developed a way to very quickly prototype microfluidic devices in plastic, rather than the usual PDMS.  The goal is to be able to work with a wide range of materials with properties tailored to the application and to develop new designs efficiently.  Read the paper

FSRS Study of Ultrafast Azobenzene Dynamics in PCCP

posted Aug 2, 2012, 3:10 PM by Ryan Leverenz


David Hoffman published his work detailing the structural dynamics of an azobenzene derivative using Femtosecond stimulated Raman in Physical Chemistry Chemical Physics.

Single cell DNA purification and analysis in Angewandte Chemie

posted Aug 2, 2012, 3:08 PM by Ryan Leverenz   [ updated Aug 2, 2012, 3:09 PM ]


Richard Novak and Yong Zeng published their work on using agarose for high-throughput single cell DNA extraction and analysis in Angwandte Chemie. The paper got selected for the "Hot Papers" category and an image of their system made it onto the frontispiece.

Read the article here.

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