February 2023; Volume 354

Anti-PEG antibodies before and after a first dose of Comirnaty® (mRNA-LNP-based SARS-CoV-2 vaccine)

Yaelle Bavli, Bing-Mae Chen, Guy Gross, Alon Hershko, ... Yechezkel Barenholz


Microenvironment-responsive anti-PD-L1 × CD3 bispecific T-cell engager for solid tumor immunotherapy

Dingkang Liu, Lichen Bao, Haichao Zhu, Yali Yue, ... Jun Yin


Drug delivery as a sustainable avenue to future therapies

Gregor Fuhrmann


January 2023; Volume 353

Polymer- and lipid-based gene delivery technology for CAR T cell therapy

Inês S. Pinto, Rosemeyre A. Cordeiro, Henrique Faneca


High drug-loading and controlled-release hydroxyphenyl-polyacrylate adhesive for transdermal patch

Shuai Zhang, Chao Liu, Yilin Song, Jiuheng Ruan, ... Liang Fang


The mechanisms of anti-PEG immune response are different in the spleen and the lymph nodes

Philippe Grenier, Valérie Chénard, Nicolas Bertrand


December 2022; Volume 352

Strengthening scientific credibility against misinformation and disinformation: Where do we stand now?

Wei Jeng, Yen-Ming Huang, Hsun-Yu Chan, Chi-Chuan Wang


Dibenzocyclooctyne linked lysine-cyclodextrin for efficient intranucleus delivery of proteins

Zhiying Zeng, Changying Li, Yupeng Zhu, Lan Yang, ... Xuli Feng


October 2022; Volume 350

Electrospun patch delivery of anti-TNFα F(ab) for the treatment of inflammatory oral mucosal disease

Jake G. Edmans, Bethany Ollington, Helen E. Colley, Martin E. Santocildes-Romero, ... Craig Murdoch


A lipid nanoparticle platform for mRNA delivery through repurposing of cationic amphiphilic drugs

Bram Bogaert, Félix Sauvage, Roberta Guagliardo, Cristina Muntean, ... Koen Raemdonck


Impact of doubling peptide length on in vivo hydrogel stability and sustained drug release

Julie Heremans, Lucie Chevillard, Morgane Mannes, Jessica Mangialetto, ... Charlotte Martin


September 2022; Volume 349

Tumor cell-derived extracellular vesicles for breast cancer specific delivery of therapeutic P53

Yuxuan Jiao, Yunzhi Tang, Yuan Li, Chao Liu, ... Yan-Qing Guan


Ultrasound-mediated delivery of novel tau-specific monoclonal antibody enhances brain uptake but not therapeutic efficacy

Rinie Bajracharya, Esteban Cruz, Jürgen Götz, Rebecca M. Nisbet


August 2022; Volume 348

Diboronate crosslinking: Introducing glucose specificity in glucose-responsive dynamic-covalent networks

Yuanhui Xiang, Sijie Xian, Rachel C. Ollier, Sihan Yu, ... Matthew J. Webber


Modulating albumin-mediated transport of peptide-drug conjugates for antigen-specific Treg induction

Chun Yin Jerry Lau, Naomi Benne, Bo Lou, Olga Zharkova, ... Enrico Mastrobattista


July 2022; Volume 347

Biopharmaceutical nanoclusters: Towards the self-delivery of protein and peptide therapeutics

Mia Danielsen, Casper Hempel, Thomas L. Andresen, Andrew J. Urquhart


Dissolvable polymer microneedles for drug delivery and diagnostics

Masood Ali, Sarika Namjoshi, Heather A.E Benson, Yousuf Mohammed, Tushar Kumeria


Biomimetic nanoparticles for effective mild temperature photothermal therapy and multimodal imaging

Xian Shu, Yi Chen, Ping Yan, Yun Xiang, ... Xintao Shuai


In vitro-in vivo correlation of PLGA microspheres: Effect of polymer source variation and temperature

Bo Wan, Quanying Bao, Diane J. Burgess


June 2022; Volume 346

Delivery of sorafenib by myofibroblast-targeted nanoparticles for the treatment of renal fibrosis

Hui-Teng Cheng, Hsi-Chien Huang, Tsung-Ying Lee, Yu-Hui Liao, ... Yunching Chen


May 2022; Volume 343

Biomaterials as therapeutic drug carriers for inflammatory bowel disease treatment

Chi-Pin James Wang, Min Ji Byun, Se-Na Kim, Wooram Park, ... Chun Gwon Park


Rationally designed nanoparticle delivery of Cas9 ribonucleoprotein for effective gene editing

Se-Youl Chae, Euihwan Jeong, Seounghun Kang, Yeajee Yim, ... Dal-Hee Min


April 2022; Volume 344

Bispecific T-cell engagers non-covalently decorated drug-loaded PEGylated nanocarriers for cancer immunochemotherapy

Wei-Jie Cheng, Kuo-Hsiang Chuang, Yu-Ju Lo, Michael Chen, ... Ming-Thau Sheu


Leveraging biomaterials for enhancing T cell immunotherapy

Ziyan Liao, Wentao Zhang, Hanqi Zheng, Yanfang Wang, ... Zhen Gu


March 2022; Volume 343

No articles of interest


February 2022; Volume 342

Enhanced nose-to-brain delivery of siRNA using hyaluronan-enveloped nanomicelles for glioma therapy

YuLing Yang, XueYan Zhang, SiWen Wu, Rui Zhang, ... Li Yang


Development of hot-melt extruded drug/polymer matrices for sustained delivery of meloxicam

Yun-Chu Chen, Dana E. Moseson, Coralie A. Richard, Monica R. Swinney, ... Yoon Yeo


Delivery of CRISPR-Cas tools for in vivo genome editing therapy: Trends and challenges

Eman A. Taha, Joseph Lee, Akitsu Hotta


January 2022; Volume 341

Synthesis of block copolymers used in polymersome fabrication: Application in drug delivery

Maliheh Hasannia, Ali Aliabadi, Khalil Abnous, Seyed Mohammad Taghdisi, ... Mona Alibolandi


Emerging landscape of cell-penetrating peptide-mediated nucleic acid delivery and their utility in imaging, gene-editing, and RNA-sequencing

Jingping Geng, Xuan Xia, Lin Teng, Lidan Wang, ... Hu Wang


Fabricating scalable, personalized wound dressings with customizable drug loadings via 3D printing

Jia Heng Teoh, Sook Muay Tay, Jerry Fuh, Chi-Hwa Wang


Lipid nanoparticle chemistry determines how nucleoside base modifications alter mRNA delivery

Jilian R. Melamed, Khalid A. Hajj, Namit Chaudhary, Daria Strelkova, ... Kathryn A. Whitehead


December 10, 2021; Volume 340

Localized delivery of immunotherapeutics: A rising trend in the field

Jie Wang, Yukun Zhang, Jiuchan Pi, Dongming Xing, Chao Wang

Rational preparation and application of a mRNA delivery system with cytidinyl/cationic lipid

Lei Li, Jinrong Long, Ye Sang, Xin Wang, ... Shengqi Wang


November 10, 2021; Volume 339

Hypoxia-responsive block copolymer polyprodrugs for complementary photodynamic-chemotherapy

Qinghao Zhou, Fathelrahman Mohammed, Yuheng Wang, Jingbo Wang, ... Zhishen Ge


Coiled coil exposure and histidine tags drive function of an intracellular protein drug carrier

Anshul Dhankher, Wei Lv, William T. Studstill, Julie A. Champion


October 10, 2021; Volume 338

Ionic liquids as a useful tool for tailoring active pharmaceutical ingredients

Xiying Wu, Quangang Zhu, Zhongjian Chen, Wei Wu, ... Jianping Qi


Revealing the importance of carrier-cargo association in delivery of insulin and lipidated insulin

Ragna Guldsmed Diedrichsen, Stine Harloff-Helleberg, Ulrich Werner, Melissa Besenius, ... Hanne Mørck Nielsen


Biomimetic cell membrane-coated DNA nanoparticles for gene delivery to glioblastoma

Sangrok Han, Youngki Lee, Minhyung Lee


Engineered insulin-polycation complexes for glucose-responsive delivery with high insulin loading

Lisa R. Volpatti, Delaney M. Burns, Arijit Basu, Robert Langer, Daniel G. Anderson


Synergistic gene delivery by self-assembled nanocomplexes using fusion peptide and calcium phosphate

Soon Gil Jeong, Yeong Chae Ryu, Byeong Hee Hwang


Asymmetric polymersomes, from the formation of asymmetric membranes to the application on drug delivery

Chen Guo, Haoyang Yuan, Yu Zhang, Tian Yin, ... Xing Tang


Self-assembled polymeric micelle as a novel mRNA delivery carrier

Jin Ren, Yiming Cao, Lei Li, Xin Wang, ... Shengqi Wang



September 10, 2021: Volume 337

Polymeric nanomedicines targeting hematological malignancies

Wenxing Gu, Ruobing Qu, Fenghua Meng, Jeroen J.L.M. Cornelissen, Zhiyuan Zhong


Solid self emulsifying drug delivery system: Superior mode for oral delivery of hydrophobic cargos

Indrani Maji, Srushti Mahajan, Anitha Sriram, Pravin Medtiya, ... Pankaj Kumar Singh


High-throughput evaluation of polymeric nanoparticles for tissue-targeted gene expression using barcoded plasmid DNA

Jayoung Kim, Hannah J. Vaughan, Camila G. Zamboni, Joel C. Sunshine, Jordan J. Green


Glycosylation of PAMAM dendrimers significantly improves tumor macrophage targeting and specificity in glioblastoma

Rishi Sharma, Kevin Liaw, Anjali Sharma, Ambar Jimenez, ... Rangaramanujam M. Kannan


Selective transferrin coating as a facile strategy to fabricate BBB-permeable and targeted vesicles for potent RNAi therapy of brain metastatic breast cancer in vivo

Yaohua Wei, Yinping Sun, Jingjing Wei, Xinyun Qiu, ... Zhiyuan Zhong


July 10, 2021; Volume 335

The reversal of chemotherapy-induced multidrug resistance by nanomedicine for cancer therapy

Shangui Liu, Abdur Rauf Khan, Xiaoye Yang, Bo Dong, ... Guangxi Zhai

Microneedles for gene and drug delivery in skin cancer therapy

Defu Zhi, Ting Yang, Tingyu Zhang, Mei Yang, ... Ryan F. Donnelly

Biotherapeutic-loaded injectable hydrogels as a synergistic strategy to support myocardial repair after myocardial infarction

Zhi Zheng, Ying Tan, Yi Li, Ying Liu, ... Hua Wei

Tailoring of P-glycoprotein for effective transportation of actives across blood-brain-barrier

Nazneen Pathan, Pravin Shende

PEG-polyaminoacid based micelles for controlled release of doxorubicin: Rational design, safety and efficacy study

Silvia Brunato, Francesca Mastrotto, Federica Bellato, Chiara Bastiancich, ... Paolo Caliceti

Controllable multi-phase protein release from in-situ hydrolyzable hydrogel

Chi Ming Laurence Lau, Ghodsiehsadat Jahanmir, Yu Yu, Ying Chau

Novel polyester-based thermoplastic elastomers for 3D-printed long-acting drug delivery applications

Ioannis Koutsamanis, Amrit Paudel, Carolina Patricia Alva Zúñiga, Laura Wiltschko, Martin Spoerk


June 10, 2021; Volume 334

Harnessing amphiphilic polymeric micelles for diagnostic and therapeutic applications: Breakthroughs and bottlenecks

Jaskiran Kaur, Vijay Mishra, Sachin Kumar Singh, Monica Gulati, ... Kuppusamy Gowthamarajan

Nanobodies as efficient drug-carriers: Progress and trends in chemotherapy

Sandeep Surendra Panikar, Nehla Banu, Jesse Haramati, Susana del Toro-Arreola, ... Pedro Salas

Sustained release of peptides and proteins from polymeric nanocarriers produced by inverse Flash NanoPrecipitation

Chester E. Markwalter, Robert F. Pagels, Ava N. Hejazi, Kurt D. Ristroph, ... Robert K. Prud'homme

Anti-PEG IgM production and accelerated blood clearance phenomenon after the administration of PEGylated exosomes in mice

Sherif E. Emam, Nehal E. Elsadek, Amr S. Abu Lila, Haruka Takata, ... Tatsuhiro Ishida


May 10, 2021; Volume 333

Delivery of nanoparticle antigens to antigen-presenting cells: from extracellular specific targeting to intracellular responsive presentation

Fei Wang, Aftab Ullah, Xuelian Fan, Zhou Xu, ... Gang Chen

BBB-crossing adeno-associated virus vector: An excellent gene delivery tool for CNS disease treatment

Wenli Chen, Shun Yao, Jie Wan, Yu Tian, ... Xiaochun Zhang

Nano-delivery systems focused on tumor microenvironment regulation and biomimetic strategies for treatment of breast cancer metastasis

Xiaoyan Gu, Yunzhen Gao, Ping Wang, Lixin Wang, ... Nianping Feng

Mechanistic investigation of thermosensitive liposome immunogenicity and understanding the drivers for circulation half-life: A polyethylene glycol versus 1,2-dipalmitoyl-sn-glycero-3-phosphodiglycerol study

Wouter J.M. Lokerse, Artur Lazarian, Alisa Kleinhempel, Matteo Petrini, ... Lars H. Lindner

Geometry encoded functional programming of tumor homing peptides for targeted drug delivery

Ruchika Goyal, Gaurav Jerath, R. Akhil, Aneesh Chandrasekharan, ... Vibin Ramakrishnan

Engineering a sustained release vaccine with a pathogen-mimicking manner for robust and durable immune responses

Yingying Hou, Rong Liu, Xiaoyu Hong, Yunting Zhang, ... Xun Sun

Design of PD-1-decorated nanocages targeting tumor-draining lymph node for promoting T cell activation

Gi Beom Kim, Hyo-Dong Sung, Gi-Hoon Nam, Wonjun Kim, ... In-San Kim

Charge-reversal nanocomolexes-based CRISPR/Cas9 delivery system for loss-of-function oncogene editing in hepatocellular carcinoma

Jing-Jun Nie, Yanli Liu, Yu Qi, Nasha Zhang, ... Fu-Jian Xu

April 10, 2021 (Volume 332)

Polymeric micelles in cancer therapy: State of the art

Balaram Ghosh, Swati Biswas

Polymeric micelles in drug delivery: An insight of the techniques for their characterization and assessment in biorelevant conditions

M. Ghezzi, S. Pescina, C. Padula, P. Santi, ... S. Nicoli

Achieving highly efficient gene transfer to the bladder by increasing the molecular weight of polymer-based nanoparticles

Gang Li, Shanshan He, Andreas G. Schätzlein, Robert M. Weiss, ... Ijeoma F. Uchegbu

Co-encapsulation of Cas9 mRNA and guide RNA in polyplex micelles enables genome editing in mouse brain

Saed Abbasi, Satoshi Uchida, Kazuko Toh, Theofilus A. Tockary, ... Kazunori Kataoka

March 10, 2021 (Volume 331)

Development of nanoparticle-delivery systems for antiviral agents: A review

Rana Delshadi, Akbar Bahrami, David Julian McClements, Matthew D. Moore, Leonard Williams

Improving silymarin oral bioavailability using silica-installed redox nanoparticle to suppress inflammatory bowel disease

Thu-Ha Thi Nguyen, Nhu-Thuy Trinh, Han Ngoc Tran, Hao Thi Tran, ... Yukio Nagasaki

Polymeric delivery systems for nucleic acid therapeutics: Approaching the clinic

Annette I.S. van den Berg, Chae-Ok Yun, Raymond M. Schiffelers, Wim E. Hennink

February 10, 2021 (Volume 330)

Intracellular delivery of immunoglobulin G at nanomolar concentrations with domain Z-fused multimeric α-helical cell penetrating peptides

Seung-Eun Chong, Jae Hoon Oh, Kyungjin Min, Sohyun Park, ... Yan Lee

Advances in biodegradable and injectable hydrogels for biomedical applications

Yi Li, Hong Yu Yang, Doo Sung Lee

January 10, 2021 (Volume 239)

Learning from past failures: Challenges with monoclonal antibody therapies for COVID-19

Samuel K. Lai, Morgan D. McSweeney, Raymond J. Pickles

In vivo tracking of bioorthogonally labeled T-cells for predicting therapeutic efficacy of adoptive T-cell therapy

Woojun Kim, Hong Yeol Yoon, Seungho Lim, Patrick S. Stayton, ... Ick Chan Kwon



December 10, 2020 (Volume 238)

Transport of PEGylated-PLA nanoparticles across a blood brain barrier model, entry into neuronal cells and in vivo brain bioavailability

Jean-Michel Rabanel, Pierre-Alexandre Piec, Sarra Landri, Shunmoogum A. Patten, Charles Ramassamy

Overcoming resistance to rituximab in relapsed non-Hodgkin lymphomas by antibody-polymer drug conjugates actively targeted by anti-CD38 daratumumab

Ondřej Lidický, Pavel Klener, Daniela Machová, Petra Vočková, ... Tomáš Etrych

November 10, 2020 (Volume 237)

Advancements in the co-formulation of biologic therapeutics

Veeren M. Chauhan, Hongyu Zhang, Paul A. Dalby, Jonathan W. Aylott

The biological fate of orally administered mPEG-PDLLA polymeric micelles

Haisheng He, Luting Wang, Yuhua Ma, Yinqian Yang, ... Wei Wu

October 10, 2020 (Volume 236)

Chitosan hydrogels for sustained drug delivery

S. Peers, A. Montembault, C. Ladavière

Intravitreal hydrogels for sustained release of therapeutic proteins

Blessing C. Ilochonwu, Arto Urtti, Wim E. Hennink, Tina Vermonden

Surface functionalization of exosomes for target-specific delivery and in vivo imaging & tracking: Strategies and significance

Shubham Salunkhe, Dheeraj, Moumita Basak, Deepak Chitkara, Anupama Mittal

Design of amino acid-based self-assembled nano-drugs for therapeutic applications

Long Binh Vong, Nhu-Thuy Trinh, Yukio Nagasaki

September 10, 2020 (Volume 235)

Taking advantage of cellular uptake of ferritin nanocages for targeted drug delivery

Barbora Tesarova, Kamil Musilek, Simona Rex, Zbynek Heger

A novel mitochondrial targeted hybrid peptide modified HPMA copolymers for breast cancer metastasis suppression

Qiuyi Li, Jiatao Yang, Cheng Chen, Xi Lin, ... Yuan Huang

August 10, 2020: Volume 324

Poly(L-glutamic acid)-co-poly(ethylene glycol) block copolymers for protein conjugation

Katia Maso, Antonella Grigoletto, Lucia Raccagni, Marino Bellini, ... Gianfranco Pasut

Detailed cellular assessment of albumin-bound oligonucleotides: Increased stability and lower non-specific cell uptake

Aurélie Lacroix, Hassan H. Fakih, Hanadi F. Sleiman

A peptide for transcellular cargo delivery: Structure-function relationship and mechanism of action

Alexander Komin, Maxim I. Bogorad, Ran Lin, Honggang Cui, ... Kalina Hristova

July 2019: Volume 323

Tumor microenvironment-induced structure changing drug/gene delivery system for overcoming delivery-associated challenges

Min Zhang, Xinli Guo, Mingfu Wang, Kehai Liu

Micelleplexes as nucleic acid delivery systems for cancer-targeted therapies

Miguel Pereira-Silva, Ivana Jarak, Carmen Alvarez-Lorenzo, Angel Concheiro, ... Ana Figueiras

Application of star poly(ethylene glycol) derivatives in drug delivery and controlled release

Xiaobao Zhao, Jingxing Si, Dongsheng Huang, Ke Li, ... Meihua Sui

Thermosensitive hydrogels as sustained drug delivery system for CTLA-4 checkpoint blocking antibodies

Chih Kit Chung, Marieke F. Fransen, Koen van der Maaden, Yaima Campos, ... Luis J. Cruz

Photo-responsive supramolecular hyaluronic acid hydrogels for accelerated wound healing

Weiyi Zhao, Yang Li, Xiang Zhang, Rui Zhang, ... Fu-Jian Xu

Bacterial outer membrane vesicles as a platform for biomedical applications: An update

Min Li, Han Zhou, Chen Yang, Yi Wu, ... Yucai Wang

June 2019: Volume 322

Analysing the nanoparticle-protein corona for potential molecular target identification

Chandra Kumar Elechalawar, Md. Nazir Hossen, Lacey McNally, Resham Bhattacharya, Priyabrata Mukherjee

Ultrasound-responsive polymersomes capable of endosomal escape for efficient cancer therapy

Ping Wei, Min Sun, Bo Yang, Jiangang Xiao, Jianzhong Du

Polyplex transfection from intracerebroventricular delivery is not significantly affected by traumatic brain injury

David J. Peeler, Nicholas Luera, Philip J. Horner, Suzie H. Pun, Drew L. Sellers

Improving antibody-based therapies by chemical engineering of antibodies with multimeric cell-penetrating peptides for elevated intracellular delivery

Max Sauter, Matthias Strieker, Christian Kleist, Artjom Wischnjow, ... Walter Mier

Stepwise dual targeting and dual responsive polymer micelles for mitochondrion therapy

Xiaobin Zhang, Yi Wang, Guoqing Wei, Jingya Zhao, ... Shaobing Zhou

Genome editing of mutant KRAS through supramolecular polymer-mediated delivery of Cas9 ribonucleoprotein for colorectal cancer therapy

Tao Wan, Yuxuan Chen, Qi Pan, Xiaojie Xu, ... Yuan Ping

May 2019: Volume 321

Synthesis and functionalization of hyperbranched polymers for targeted drug delivery

Alireza Kavand, Nicolas Anton, Thierry Vandamme, Christophe A. Serra, Delphine Chan-Seng

April 2019: Volume 320

Hypoxia-sensitive supramolecular nanogels for the cytosolic delivery of ribonuclease A as a breast cancer therapeutic

Xinghui Si, Sheng Ma, Yudi Xu, Dawei Zhang, ... Xuesi Chen

Tailoring guanidyl-rich polymers for efficient cytosolic protein delivery

Jia Lv, Echuan Tan, Yuqing Wang, Qianqian Fan, ... Yiyun Cheng

CD44-targeted vesicles encapsulating granzyme B as artificial killer cells for potent inhibition of human multiple myeloma in mice

Yinan Zhong, Fenghua Meng, Wen Zhang, Bin Li, ... Zhiyuan Zhong

Injectable biodegradable bi-layered capsule for sustained delivery of bevacizumab in treating wet age-related macular degeneration

Pengfei Jiang, Francisco J. Chaparro, Clayton T. Cuddington, Andre F. Palmer, ... Katelyn E. Swindle-Reilly

March 2019: Volume 319

Current challenges and emerging opportunities of CAR-T cell therapies

Teresa R. Abreu, Nuno A. Fonseca, Nélio Gonçalves, João Nuno Moreira

Toward understanding polymer micelle stability: Density ultracentrifugation offers insight into polymer micelle stability in human fluids

Timothy D. Langridge, Richard A. Gemeinhart

Multivalent HER2-binding polymer conjugates facilitate rapid endocytosis and enhance intracellular drug delivery

D. Christopher Radford, Jiyuan Yang, Mai C. Doan, Lian Li, ... Jindřich Kopeček

Systemic and brain delivery of leptin via intranasal coadministration with cell-penetrating peptides and its therapeutic potential for obesity

El-Sayed Khafagy, Noriyasu Kamei, Yui Fujiwara, Haruka Okumura, ... Mariko Takeda-Morishita

February 2019: Volume 318

Length effect of stimuli-responsive block copolymer prodrug filomicelles on drug delivery efficiency

Wendong Ke, Nannan Lu, Abd Al-Wali Mohammed M. Japir, Qinghao Zhou, ... Zhishen Ge

January 2019: Volume 317

Functional polymeric nerve guidance conduits and drug delivery strategies for peripheral nerve repair and regeneration

Ohan S. Manoukian, Jiana T. Baker, Swetha Rudraiah, Michael R. Arul, ... Sangamesh G. Kumbar

Dual and multi-targeted nanoparticles for site-specific brain drug delivery

Yan Luo, Hang Yang, Yi-Fan Zhou, Bo Hu

December 2019: Volume 316

Polymeric siRNA gene delivery – transfection efficiency versus cytotoxicity

Anna Kargaard, Joost P.G. Sluijter, Bert Klumperman

December 2019: Volume 315

No relevant articles.

November 2019: Volume 314

No relevant articles.

November 2019: Volume 313

Selectively targeting tumor-associated macrophages and tumor cells with polymeric micelles for enhanced cancer chemo-immunotherapy

Xiao Wei, Lingqiao Liu, Xilin Li, Yi Wang, ... Shaobing Zhou

October 2019: Volumes 311-312

Folate-displaying exosome mediated cytosolic delivery of siRNA avoiding endosome trapping

Zhen Zheng, Zhefeng Li, Congcong Xu, Bin Guo, Peixuan Guo

September 2019: Volume 310

No relevant articles.

September 2019: Volume 309

Cell-penetrating peptide: a means of breaking through the physiological barriers of different tissues and organs

Jiangkang Xu, Abdur Rauf Khan, Manfei Fu, Rujuan Wang, ... Guangxi Zhai

Perturbation of mitochondrial bioenergetics by polycations counteracts resistance to BRAFE600 inhibition in melanoma cells

Arnaldur Hall, Scott Maynard, Lin-Ping Wu, Joanna Maria Merchut-Maya, ... Jiri Bartek

August 2019: Volume 308

New insight into isolation, identification techniques and medical applications of exosomes

Xiao-Xia Yang, Chao Sun, Lei Wang, Xiu-Li Guo

The size and composition of polymeric nanocapsules dictate their interaction with macrophages and biodistribution in zebrafish

José Crecente-Campo, Jorge Guerra-Varela, Mercedes Peleteiro, Carlha Gutiérrez-Lovera, ... María José Alonso

August 2019: Volume 307

Chemical modulation of siRNA lipophilicity for efficient delivery

Wanyi Tai

Crossing biological barriers with nanogels to improve drug delivery performance

Julio César Cuggino, Ernesto Rafael Osorio Blanco, Luis Marcelino Gugliotta, Cecilia Inés Alvarez Igarzabal, Marcelo Calderón

The hard protein corona of stealth liposomes is sparse

Kasper Kristensen, Trine B. Engel, Allan Stensballe, Jens B. Simonsen, Thomas L. Andresen

July 2019: Volume 306

Systematic review of targeted extracellular vesicles for drug delivery – Considerations on methodological and biological heterogeneity

Johann Mar Gudbergsson, Katrine Jønsson, Jens Bæk Simonsen, Kasper Bendix Johnsen

July 2019: Volume 305

Cationic block amphiphiles show anti-mitochondrial activity in multi-drug resistant breast cancer cells

Petro P. Czupiel, Vianney Delplace, Molly S. Shoichet

Therapeutic mRNA delivery to leukocytes

Yasmin Granot-Matok, Edo Kon, Niels Dammes, Gilad Mechtinger, Dan Peer

July 2019: Volume 304

Cell-penetrating mechanism of intracellular targeting albumin: Contribution of macropinocytosis induction and endosomal escape

Shota Ichimizu, Hiroshi Watanabe, Hitoshi Maeda, Keisuke Hamasaki, ... Toru Maruyama

June 2019: Volume 303

Polymersome nanoreactors with tumor pH-triggered selective membrane permeability for prodrug delivery, activation, and combined oxidation-chemotherapy

Jean Felix Mukerabigwi, Wei Yin, Zengshi Zha, Wendong Ke, ... Zhishen Ge

May 2019: Volume 302

No relevant articles.

May 2019: Volume 301

Current strategies in extending half-lives of therapeutic proteins

Rahela Zaman, Rowshan Ara Islam, Nabilah Ibnat, Iekhsan Othman, ... Ezharul Hoque Chowdhury

Pore-forming bioinks to enable spatio-temporally defined gene delivery in bioprinted tissues

T. Gonzalez-Fernandez, S. Rathan, C. Hobbs, P. Pitacco, ... D.J. Kelly

April 2019: Volume 300

Controlling and quantifying the stability of amino acid-based cargo within polymeric delivery systems

Whitney Nicole Souery, Shreedevi Arun Kumar, Daniel Prasca-Chamorro, David Mitchell Moore, ... Corey J. Bishop

March 2019: Volume 299

No relevant articles.

March 2019: Volume 298

No relevant articles.

March 2019: Volume 297

Local delivery of stabilized chondroitinase ABC degrades chondroitin sulfate proteoglycans in stroke-injured rat brains

Marian H. Hettiaratchi, Matthew J. O'Meara, Carter J. Teal, Samantha L. Payne, ... Molly S. Shoichet

February 2019: Volume 296

No relevant articles.

February 2019: Volume 295

Alginate/chitosan microparticles for gastric passage and intestinal release of therapeutic protein nanoparticles

Kevin Ling, Huixia Wu, Andrew S. Neish, Julie A. Champion

Januray 2019: Volume 294

Applications of π-π stacking interactions in the design of drug-delivery systems

Wan-Ru Zhuang, Yi Wang, Peng-Fei Cui, Lei Xing, ... Yu-Kyoung Oh

Januray 2019: Volume 293

pH-Sensitive morphological transitions in polymeric tadpole assemblies for programmed tumor therapy

Cunfeng Song, Tongtong Lin, Qiang Zhang, S. Thayumanavan, Lei Ren

Modular core-shell polymeric nanoparticles mimicking viral structures for vaccination

Bo Lou, Ans De Beuckelaer, Eger Boonstra, Dandan Li, ... Wim E. Hennink

December 2018: Volume 292

Peptide-based targeted therapeutics: Focus on cancer treatment

Fatemeh Araste, Khalil Abnous, Maryam Hashemi, Seyed Mohammad Taghdisi, ... Mona Alibolandi

Biomaterials for vaccine-based cancer immunotherapy

Rui Zhang, Margaret M. Billingsley, Michael J. Mitchell

The impact of digestion is essential to the understanding of milk as a drug delivery system for poorly water soluble drugs

Ben J. Boyd, Malinda Salim, Andrew J. Clulow, Gisela Ramirez, ... Adrian Hawley

Effective treatment of the primary tumor and lymph node metastasis by polymeric micelles with variable particle sizes

Ling Mei, Jingdong Rao, Yayuan Liu, Man Li, ... Qin He

Epirubicin-loaded polymeric micelles effectively treat axillary lymph nodes metastasis of breast cancer through selective accumulation and pH-triggered drug release

Tsukasa Chida, Yutaka Miura, Horacio Cabral, Takahiro Nomoto, ... Nobuhiro Nishiyama

Boosting RNAi therapy for orthotopic glioblastoma with nontoxic brain-targeting chimaeric polymersomes

Yanan Shi, Yu Jiang, Jinsong Cao, Weijing Yang, ... Zhiyuan Zhong

December 2018: Volume 291

Recent progress of drug nanoformulations targeting to brain

Abdur Rauf Khan, Xiaoye Yang, Manfei Fu, Guangxi Zhai

Bifunctional peptide hybrids targeting the matrix of mitochondria

Annika Klimpel, Ines Neundorf

November 2018: Volume 290

The application of nanotechnology in immune checkpoint blockade for cancer treatment

Huan Deng, Zhiping Zhang

Peptide-decorated polymeric nanomedicines for precision cancer therapy

Huanli Sun, Yangyang Dong, Jan Feijen, Zhiyuan Zhong

Biocompatible bacteria-derived vesicles show inherent antimicrobial activity

Eilien Schulz, Adriely Goes, Ronald Garcia, Fabian Panter, ... Gregor Fuhrmann

Granzyme B-loaded, cell-selective penetrating and reduction-responsive polymersomes effectively inhibit progression of orthotopic human lung tumor in vivo

Weijing Yang, Yaohua Wei, Liang Yang, Jian Zhang, ... Fenghua Meng

November 2018: Volume 289

Extracellular vesicles: intelligent delivery strategies for therapeutic applications

Alice Pinheiro, Andreia M. Silva, José H. Teixeira, Raquel M. Gonçalves, ... Susana G. Santos

Exosomes: natural nanoparticles as bio shuttles for RNAi delivery

Saber Ghazizadeh Darband, Mohammad Mirza-Aghazadeh-Attari, Mojtaba Kaviani, Ainaz Mihanfar, ... Maryam Majidinia

A filter-free blood-brain barrier model to quantitatively study transendothelial delivery of nanoparticles by fluorescence spectroscopy

Edwin De Jong, David S. Williams, Loai K.E.A. Abdelmohsen, Jan C.M. Van Hest, Inge S. Zuhorn

October 2018: Volume 288

No relevant articles.

October 2018: Volume 287

The molecularly imprinted polymer essentials: curation of anticancer, ophthalmic, and projected gene therapy drug delivery systems

Christian Antonio Tuwahatu, Chi Chung Yeung, Yun Wah Lam, Vellaisamy Arul Lenus Roy

September 2018: Volume 286

Bilayer polymeric nanocapsules: A formulation approach for a thermostable and adjuvanted E. coli antigen vaccine

José Crecente-Campo, Silvia Lorenzo-Abalde, Azucena Mora, Juan Marzoa, ... María José Alonso

Dual functionalized liposome-mediated gene delivery across triple co-culture blood brain barrier model and specific in vivo neuronal transfection

Bruna dos Santos Rodrigues, Hiroshi Oue, Amrita Banerjee, Takahisa Kanekiyo, Jagdish Singh

Single-chain polymer nanoparticles in controlled drug delivery and targeted imaging

A. Pia P. Kröger, Jos M.J. Paulusse

September 2018: Volume 285

Monocultures of primary porcine brain capillary endothelial cells: Still a functional in vitro model for the blood-brain-barrier

Hans-Joachim Galla

August 2018: Volume 284

Cell penetrating peptides in ocular drug delivery: State of the art

S. Pescina, C. Ostacolo, I.M. Gomez-Monterrey, M. Sala, ... S. Nicoli

August 2018: Volume 283

Nanocapsule-mediated cytosolic siRNA delivery for anti-inflammatory treatment

Ying Jiang, Joseph Hardie, Yuanchang Liu, Moumita Ray, ... Vincent M. Rotello

July 2018: Volume 282

Supramolecular self assembly of nanodrill-like structures for intracellular delivery

N. Ashwanikumar, Justin S. Plaut, Barmak Mostofian, Siddharth Patel, ... Gaurav Sahay

Cationic polymers for non-viral gene delivery to human T cells

Brynn R. Olden, Yilong Cheng, Jonathan L. Yu, Suzie H. Pun

July 2018: Volume 281

Regulatory T cell-targeted hybrid nanoparticles combined with immuno-checkpoint blockage for cancer immunotherapy

Wenquan Ou, Raj Kumar Thapa, Liyuan Jiang, Zar Chi Soe, ... Jong Oh Kim

Advances in the slow freezing cryopreservation of microencapsulated cells

H Gurruchaga, L Saenz del Burgo, R.M Hernandez, G Orive, ... J.L Pedraz

June 2018: Volume 280

Streptavidin-mirror DNA tetrahedron hybrid as a platform for intracellular and tumor delivery of enzymes

Kyoung-Ran Kim, Dohyeon Hwang, Juhyeon Kim, Chang-Yong Lee, ... Dae-Ro Ahn

June 2018: Volume 279

Acid-sensitive hybrid polymeric micelles containing a reversibly activatable cell-penetrating peptide for tumor-specific cytoplasm targeting

Baoqiang Tang, Jennica L. Zaro, Yan Shen, Qian Chen, ... Chunmeng Sun

Mechanistic studies of a cell-permeant peptide designed to enhance myosin light chain phosphorylation in polarized intestinal epithelia

Khaled Almansour, Alistair Taverner, Ian M. Eggleston, Randall J. Mrsny

May 2018: Volume 278

Highly efficacious and specific anti-glioma chemotherapy by tandem nanomicelles co-functionalized with brain tumor-targeting and cell-penetrating peptides

Yaqin Zhu, Yu Jiang, Fenghua Meng, Chao Deng, ... Zhiyuan Zhong

Preclinical evaluation of mRNA trimannosylated lipopolyplexes as therapeutic cancer vaccines targeting dendritic cells

A. Le Moignic, V. Malard, T. Benvegnu, L. Lemiègre, ... V. Mateo

The novelty bubble

Jean-Christophe Leroux

May 2018: Volume 277

Design and tuning of a cell-penetrating albumin derivative as a versatile nanovehicle for intracellular drug delivery

Shota Ichimizu, Hiroshi Watanabe, Hitoshi Maeda, Keisuke Hamasaki, ... Toru Maruyama

April 2018: Volume 276

No relevant articles.

April 2018: Volume 275

Synergism between a cell penetrating peptide and a pH-sensitive cationic lipid in efficient gene delivery based on double-coated nanoparticles

Ikramy A. Khalil, Seigo Kimura, Yusuke Sato, Hideyoshi Harashima

March 2018: Volume 274

No relevant articles.

March 2018: Volume 273

High-efficiency transduction of spinal cord motor neurons by intrauterine delivery of integration-deficient lentiviral vectors

Sherif G. Ahmed, Simon N. Waddington, Maria Gabriela Boza-Morán, Rafael J. Yáñez-Muñoz

February 2018: Volume 272

Amphiphilic polysaccharides as building blocks for self-assembled nanosystems: molecular design and application in cancer and inflammatory diseases

Xiaoye Yang, Xiaoqun Shi, Richard D'arcy, Nicola Tirelli, Guangxi Zhai

February 2018: Volume 271

Lipid-polymer hybrid nanocarriers for delivering cancer therapeutics

Tushar Date, Vaishnavi Nimbalkar, Jyostna Kamat, Anupama Mittal, ... Deepak Chitkara

A strong adjuvant based on glycol-chitosan-coated lipid-polymer hybrid nanoparticles potentiates mucosal immune responses against the recombinant Chlamydia trachomatis fusion antigen CTH522

Fabrice Rose, Jeanette Erbo Wern, Francesca Gavins, Peter Andersen, ... Camilla Foged

January 2018: Volume 270

RNA nanoparticle distribution and clearance in the eye after subconjunctival injection with and without thermosensitive hydrogels

Zhanquan Shi, S. Kevin Li, Ponwanit Charoenputtakun, Chia-Yang Liu, ... Peixuan Guo

Nose-to-brain delivery of insulin enhanced by a nanogel carrier

Pasquale Picone, Maria Antonietta Sabatino, Lorena Anna Ditta, Antonella Amato, ... Marta Di Carl

pH-sensitive polymeric nanoparticles with antioxidant and anti-inflammatory properties against cisplatin-induced hearing loss

Sergio Martín-Saldaña, Raquel Palao-Suay, María Rosa Aguilar, Luis García-Fernández, ... Julio San Román

January 2018: Volume 269

No relevant articles.

December 2017: Volume 268

No relevant articles.

December 2017: Volume 267

No relevant articles.

November 2017: Volume 266

Delivery strategies of the CRISPR-Cas9 gene-editing system for therapeutic applications

Chang Liu, Li Zhang, Hao Liu, Kun Cheng

Cancer-derived exosomes as a delivery platform of CRISPR/Cas9 confer cancer cell tropism-dependent targeting

Seung Min Kim, Yoosoo Yang, Seung Ja Oh, Yeonsun Hong, Minkoo Seo, Mihue Jang

October 2017: Volume 264

Protease-activatable cell-penetrating peptide possessing ROS-triggered phase transition for enhanced cancer therapy

Jisang Yoo, N. Sanoj Rejinold, DaeYong Lee, Sangyong Jon, Yeu-Chun Kim

October 2017: Volume 263

Rational design of polyarginine nanocapsules intended to help peptides overcoming intestinal barriers

Zhigao Niu, Erik Tedesco, Federico Benetti, Aloïse Mabondzo, Isabella Monia Montagner, Ilaria Marigo, David Gonzalez-Touceda, Sulay Tovar, Carlos Diéguez, Manuel J. Santander-Ortega, María J. Alonso

September 2017: Volume 262

No relevant articles.

September 2017: Volume 261

The use of electronic-neutral penetrating peptides cyclosporin A to deliver pro-apoptotic peptide: A possibly better choice than positively charged TAT

Pages 174-186; Wei Gao, Xiucong Yang, Zhiqiang Lin, Bing He, Dong Mei, Dan Wang, Haoran Zhang, Hua Zhang, Wenbing Dai, Xueqing Wang, Qiang Zhang

August 2017: Volume 260

No relevant articles.

August 2017: Volume 259

Engineered polymeric nanoparticles to guide the cellular internalization and trafficking of small interfering ribonucleic acids

Pages 3-15; Amy E. Arnold, Petro Czupiel, Molly Shoichet

Nanogels for intracellular delivery of biotherapeutics

Pages 16-28; Dandan Li, Cornelus F. van Nostrum, Enrico Mastrobattista, Tina Vermonden, Wim E. Hennink

July 2017: Volume 258

No relevant articles.

July 2017: Volume 257

No relevant articles.

June 2017: Volume 256

Membrane permeation of arginine-rich cell-penetrating peptides independent of transmembrane potential as a function of lipid composition and membrane fluidity

Pages 68-78; Rike Wallbrecher, Tobias Ackels, R. Alis Olea, Marco J. Klein, Lucie Caillon, Jürgen Schiller, Petra H. Bovée-Geurts, Toin H. van Kuppevelt, Anne S. Ulrich, Marc Spehr, Merel J.W. Adjobo-Hermans, Roland Brock

June 2017: Volume 255

Human-derived fusogenic peptides for the intracellular delivery of proteins

Pages 1-11; Kei Sudo, Keisuke Niikura, Kouta Iwaki, Shunshi Kohyama, Kei Fujiwara, Nobuhide Doi

ATRP-grown protein-polymer conjugates containing phenylpiperazine selectively enhance transepithelial protein transport

Pages 270-278; Chad S. Cummings, Katherine Fein, Hironobu Murata, Rebecca L. Ball, Alan J. Russell, Kathryn A. Whitehead

May 2017: Volume 254

Sequence segregation improves non-covalent protein delivery

Pages 131-136; Federica Sgolastra, Coralie M. Backlund, E. Ilker Ozay, Brittany M. deRonde, Lisa M. Minter, Gregory N. Tew

May 2017: Volume 253

No relevant articles.

April 2017: Volume 252

No relevant articles.

April 2017: Volume 251

Delivering adjuvants and antigens in separate nanoparticles eliminates the need of physical linkage for effective vaccination

Pages 92-100; Mona O. Mohsen, Ariane C. Gomes, Gustavo Cabral-Miranda, Caroline C. Krueger, Fabiana MS Leoratti, Jens V. Stein, Martin F. Bachmann

March 2017: Volume 250

Recent developments in anticancer drug delivery using cell penetrating and tumor targeting peptides

Pages 62-76; Shama Dissanayake, William A Denny, Swarna Gamage, Vijayalekshmi Sarojini

Poly-sgRNA/siRNA ribonucleoprotein nanoparticles for targeted gene disruption

Pages 27-35; Jong Seong Ha, Jae Sung Lee, Jaepil Jeong, Hejin Kim, Juyoung Byun, Sang Ah Kim, Hee Jae Lee, Hak Suk Chung, Jong Bum Lee, Dae-Ro Ahn

March 2017: Volume 249

Self-assembled protein nanocarrier for intracellular delivery of antibody

Pages 1-10; Sung In Lim, Cyril I. Lukianov, Julie A. Champion

February 2017: Volume 248

Surface engineering tumor cells with adjuvant-loaded particles for use as cancer vaccines

Pages 1-9; Kawther K. Ahmed, Sean M. Geary, Aliasger K. Salem

February 2017: Volume 247

No relevant articles.

January 2017: Volume 246

Bioreducible branched poly(modified nona-arginine) cell-penetrating peptide as a novel gene delivery platform

Pages 142-154; Jisang Yoo, DaeYong Lee, Vipul Gujrati, N. Sanoj Rejinold, Kamali Manickavasagam Lekshmi, Saji Uthaman, Chanuk Jeong, In-Kyu Park, Sangyong Jon, Yeu-Chun Kim

January 2017: Volume 245

Rational design of protamine nanocapsules as antigen delivery carriers

Pages 62-69; José Vicente González-Aramundiz, Elena Presas, Inmaculada Dalmau-Mena, Susana Martínez-Pulgarín, Covadonga Alonso, José M Escribano, María J. Alonso, Noemi Stefánia Csaba

Tumor-targeted delivery of sunitinib base enhances vaccine therapy for advanced melanoma by remodeling the tumor microenvironment

Pages 81-94; Meirong Huo, Yan Zhao, Andrew Benson Satterlee, Yuhua Wang, Ying Xu, Leaf Huang

siRNA-cell-penetrating peptides complexes as a combinatorial therapy against chronic myeloid leukemia using BV173 cell line as model

Pages 127-136; João Miguel Freire, Inês Rego de Figueiredo, Javier Valle, Ana Salomé Veiga, David Andreu, Francisco J. Enguita, Miguel A.R.B. Castanho

December 2016: Volume 244B

CRISPR-Cas9 gene editing: Delivery aspects and therapeutic potential

Pages 139-148; Erik Oude Blenke, Martijn J.W. Evers, Enrico Mastrobattista, John van der Oost

Anti-PEG antibodies in the clinic: Current issues and beyond PEGylation

Pages 184-193; Peng Zhang, Fang Sun, Sijun Liu, Shaoyi Jiang

Targeted systemic delivery of siRNA to cervical cancer model using cyclic RGD-installed unimer polyion complex-assembled gold nanoparticles

Pages 247-256; Yu Yi, Hyun Jin Kim, Peng Mi, Meng Zheng, Hiroyasu Takemoto, Kazuko Toh, Beob Soo Kim, Kotaro Hayashi, Mitsuru Naito, Yu Matsumoto, Kanjiro Miyata, Kazunori Kataoka

December 2016: Volume 244A

No relevant articles.

December 2016: Volume 243

Camelid single-domain antibodies: A versatile tool for in vivo imaging of extracellular and intracellular brain targets

Pages 1-10; Tengfei Li, Matthias Vandesquille, Fani Koukouli, Clémence Dudeffant, Ihsen Youssef, Pascal Lenormand, Christelle Ganneau, Uwe Maskos, Christian Czech, Fiona Grueninger, Charles Duyckaerts, Marc Dhenain, Sylvie Bay, Benoît Delatour, Pierre Lafaye

Functional exosome-mimic for delivery of siRNA to cancer: in vitro and in vivo evaluation

Pages 160-171; Zhaogang Yang, Jing Xie, Jing Zhu, Chen Kang, Chiling Chiang, Xinmei Wang, Xiaobing Wang, Tairong Kuang, Feng Chen, Zhou Chen, Aili Zhang, Bo Yu, Robert J. Lee, Lesheng Teng, L. James Lee

November 2016: Volume 242

Engineering biodegradable micelles of polyethylenimine-based amphiphilic block copolymers for efficient DNA and siRNA delivery

Pages 71-79; Weiwei Wang, Maria Balk, Zijun Deng, Christian Wischke, Manfred Gossen, Marc Behl, Nan Ma, Andreas Lendlein

November 2016: Volume 241

No relevant articles.

October 2016: Volume 240

Design of smart HPMA copolymer-based nanomedicines

Pages 9-23; Jiyuan Yang, Jindřich Kopeček

Nanotechnology for protein delivery: Overview and perspectives

Pages 24-37; Mikyung Yu, Jun Wu, Jinjun Shi, Omid C. Farokhzad

Delivery of drugs and macromolecules to the mitochondria for cancer therapy

Pages 38-51; Phong Lu, Benjamin J. Bruno, Malena Rabenau, Carol S. Lim

Enzyme-triggered, cell penetrating peptide-mediated delivery of anti-tumor agents

Pages 67-76; Huining He, Lu Sun, Junxiao Ye, Ergang Liu, Sunhui Chen, Qiuling Liang, Meong Cheol Shin, Victor C. Yang

October 2016: Volume 239

No relevant articles.

September 2016: Volume 238

Quantitative study of effects of free cationic chains on gene transfection in different intracellular stages

Pages 71-79; Jinge Cai, Yanan Yue, Yanjing Wang, Zhenyu Jin, Fan Jin, Chi Wu

September 2016: Volume 237

Influenza nucleoprotein DNA vaccination by a skin targeted, dry coated, densely packed microprojection array (Nanopatch) induces potent antibody and CD8+ T cell responses

Pages 35-41; Germain J.P. Fernando, Jin Zhang, Hwee-Ing Ng, Oscar L. Haigh, Sally R. Yukiko, Mark A.F. Kendall

Albumin-binding adenoviruses circumvent pre-existing neutralizing antibodies upon systemic delivery

Pages 78-88; Luis Alfonso Rojas, Gabriela N. Condezo, Rafael Moreno, Carlos Alberto Fajardo, Marcel Arias-Badia, Carmen San Martín, Ramon Alemany

Oral delivery of anti-MDM2 inhibitor SP141-loaded FcRn-targeted nanoparticles to treat breast cancer and metastasis

Pages 101-114; Jiang-Jiang Qin, Wei Wang, Sushanta Sarkar, Ruiwen Zhang

August 2016: Volume 236

No relevant articles.

August 2016: Volume 235

Messenger RNA-based therapeutics for brain diseases: An animal study for augmenting clearance of beta-amyloid by intracerebral administration of neprilysin mRNA loaded in polyplex nanomicelles

Pages 268-275; Chin-Yu Lin, Federico Perche, Masaru Ikegami, Satoshi Uchida, Kazunori Kataoka, Keiji Itaka

Efficient mRNA delivery with graphene oxide-polyethylenimine for generation of footprint-free human induced pluripotent stem cells

Pages 222-235; Hye Yeon Choi, Tae-Jin Lee, Gwang-Mo Yang, Jaesur Oh, Jihye Won, Jihae Han, Gun-Jae Jeong, Jongpil Kim, Jin-Hoi Kim, Byung-Soo Kim, Ssang-Goo Cho

Endosomal acidic pH-induced conformational changes of a cytosol-penetrating antibody mediate endosomal escape

Pages 165-175; Ji-Sun Kim, Dong-Ki Choi, Ju-Yeon Shin, Seung-Min Shin, Seong-Wook Park, Hyun-Soo Cho, Yong-Sung Kim

July 2016: Volume 234

Orchestrating immune responses: How size, shape and rigidity affect the immunogenicity of particulate vaccines

Pages 124-134; Naomi Benne, Janine van Duijn, Johan Kuiper, Wim Jiskoot, Bram Slütter

Development of a drug delivery system for efficient alveolar delivery of a neutralizing monoclonal antibody to treat pulmonary intoxication to ricin

Pages 21-32; Renaud Respaud, Denis Marchand, Thibaut Pelat, Kam-Meng Tchou-Wong, Chad J. Roy, Christelle Parent, Maria Cabrera, Joël Guillemain, Ronan Mac Loughlin, Eric Levacher, Alexandre Fontayne, Laurence Douziech-Eyrolles, Alexandra Junqua-Moullet, Laurent Guilleminault, Philippe Thullier, Emmanuelle Guillot-Combe, Laurent Vecellio, Nathalie Heuzé-Vourc'h

July 2016: Volume 233

Thermostabilization of inactivated polio vaccine in PLGA-based microspheres for pulsatile release

Pages 101-113; Stephany Y. Tzeng, Rohiverth Guarecuco, Kevin J. McHugh, Sviatlana Rose, Evan M. Rosenberg, Yingying Zeng, Robert Langer, Ana Jaklenec

Nasal immunization with mannan-decorated mucoadhesive HPMCP microspheres containing ApxIIA toxin induces protective immunity against challenge infection with Actinobacillus pleuropneumoiae in mice

Pages 114-125; Hui-Shan Li, Min-Kyoung Shin, Bijay Singh, Sushila Maharjan, Tae-Eun Park, Sang-Kee Kang, Han-Sang Yoo, Zhong-Shan Hong, Chong-Su Cho, Yun-Jaie Choi

Self-assembled triangular DNA nanoparticles are an efficient system for gene delivery

Pages 126-135; Yingming Wang, Zaichun You, Juan Du, Hongli Li, Huaping Chen, Jingtong Li, Weijie Dong, Binfeng He, Chengde Mao, Guansong Wang

June 2016: Volume 232

CD71 targeting boosts immunogenicity of sublingually delivered influenza haemagglutinin antigen and protects against viral challenge in mice

Pages 75-82; Jamie F.S. Mann, John S. Tregoning, Yoann Aldon, Robin J. Shattock, Paul F. McKay

June 2016: Volume 231

Systemic delivery of siRNA by actively targeted polyion complex micelles for silencing the E6 and E7 human papillomavirus oncogenes

Pages 29-37; Haruka Nishida, Yoko Matsumoto, Kei Kawana, R. James Christie, Mitsuru Naito, Beob Soo Kim, Kazuko Toh, Hyun Su Min, Yu Yi, Yu Matsumoto, Hyun Jin Kim, Kanjiro Miyata, Ayumi Taguchi, Kensuke Tomio, Aki Yamashita, Tomoko Inoue, Hiroe Nakamura, Asaha Fujimoto, Masakazu Sato, Mitsuyo Yoshida, Katsuyuki Adachi, et al.

May 2016: Volume 230

A novel tyrosine-modified low molecular weight polyethylenimine (P10Y) for efficient siRNA delivery in vitro and in vivo

Pages 13-25; Alexander Ewe, Susanne Przybylski, Jana Burkhardt, Andreas Janke, Dietmar Appelhans, Achim Aigner

May 2016: Volume 229

An aptamer-antibody complex (oligobody) as a novel delivery platform for targeted cancer therapies

Pages 1-9; Kyun Heo, Sung-Won Min, Ho Jin Sung, Han Gyul Kim, Hyun Jung Kim, Yun Hee Kim, Beom Kyu Choi, Sewoon Han, Seok Chung, Eun Sook Lee, Junho Chung, In-Hoo Kim

Targeted delivery of siRNA to activated T cells via transferrin-polyethylenimine (Tf-PEI) as a potential therapy of asthma

Pages 120-129; Yuran Xie, Na Hyung Kim, Venkatareddy Nadithe, Dana Schalk, Archana Thakur, Ayşe Kılıç, Lawrence G. Lum, David J.P. Bassett, Olivia M. Merkel

Cell-penetrating peptides as noninvasive transmembrane vectors for the development of novel multifunctional drug-delivery systems

Pages 130-139; Dongdong Zhang, Jiaxi Wang, Donggang Xu

April 2016: Volume 228

No relevant articles.

April 2016: Volume 227

No relevant articles.

March 2016: Volume 226

Synthetic long peptide-based vaccine formulations for induction of cell mediated immunity: A comparative study of cationic liposomes and PLGA nanoparticles

Pages 98-106; Eleni Maria Varypataki, Ana Luisa Silva, Christophe Barnier-Quer, Nicolas Collin, Ferry Ossendorp, Wim Jiskoot

Emerging landscape of cell penetrating peptide in reprogramming and gene editing

Pages 124-137; Huiting Liu, Fanhui Zeng, Ming Zhang, Fajun Huang, Jiajun Wang, Jingjing Guo, Changbai Liu, Hu Wang

March 2016: Volume 225

No relevant articles.

February 2016: Volume 224

Targeting CXCR4/SDF-1 axis by lipopolymer complexes of siRNA in acute myeloid leukemia

Pages 8-21; Breanne Landry, Hilal Gül-Uludağ, Samarwadee Plianwong, Cezary Kucharski, Zoulika Zak, Manoj B. Parmar, Olaf Kutsch, Hongxing Jiang, Joseph Brandwein, Hasan Uludağ

February 2016: Volume 223

No relevant articles.

January 2016: Volume 222

Colonic gene silencing using siRNA-loaded calcium phosphate/PLGA nanoparticles ameliorates intestinal inflammation in vivo

Pages 86-96; Annika Frede, Bernhard Neuhaus, Robert Klopfleisch, Catherine Walker, Jan Buer, Werner Müller, Matthias Epple, Astrid M. Westendorf

January 2016: Volume 221

No relevant articles.

June 2015: Volume 208

No relevant articles.

June 2015: Volume 207

No relevant articles.

May 2015: Volume 206

No relevant articles.

May 2015: Volume 205

15 years of ATTEMPTS: A macromolecular drug delivery system based on the CPP-mediated intracellular drug delivery and antibody targeting

Pages 58-69; Junxiao Ye, Meong Cheol Shin, Qiuling Liang, Huining He, Victor C. Yang

Current and future delivery systems for engineered nucleases: ZFN, TALEN and RGEN

Pages 120-127; Qurrat Ul Ain, Jee Young Chung, Yong-Hee Kim

Delivering nitric oxide with nanoparticles

Pages 190-205; John F. Quinn, Michael R. Whittaker, Thomas P. Davis

April 2015: Volume 204

No relevant articles.

April 2015: Volume 203

Calcium–siRNA nanocomplexes: The importance of reversibility

Page 189; Kinam Park

Going beyond the liver: Progress and challenges of targeted delivery of siRNA therapeutics

Pages 1-15; Cornelia Lorenzer, Mehrdad Dirin, Anna-Maria Winkler, Volker Baumann, Johannes Winkler

Oxygen carrying microbubbles for enhanced sonodynamic therapy of hypoxic tumours

Pages 51-56; Conor McEwan, Joshua Owen, Eleanor Stride, Colin Fowley, Heather Nesbitt, David Cochrane, Constantin.C. Coussios, M. Borden, Nikolitsa Nomikou, Anthony P. McHale, John F. Callan

Calcium–siRNA nanocomplexes: What reversibility is all about

Pages 150-160; Emil Ruvinov, Olga Kryukov, Efrat Forti, Efrat Korin, Matan Goldstein, Smadar Cohen

Polymeric nanoparticles for co-delivery of synthetic long peptide antigen and poly IC as therapeutic cancer vaccine formulation

Pages 16-22; Sima Rahimian, Marieke F. Fransen, Jan Willem Kleinovink, Jonatan Riis Christensen, Maryam Amidi, Wim E. Hennink, Ferry Ossendorp

Enhanced glutathione PEGylated liposomal brain delivery of an anti-amyloid single domain antibody fragment in a mouse model for Alzheimer's disease

Pages 40-50; Maarten Rotman, Mick M. Welling, Anton Bunschoten, Maaike E. de Backer, Jaap Rip, Rob J.A. Nabuurs, Pieter J. Gaillard, Mark A. van Buchem, Silvère M. van der Maarel, Louise van der Weerd

An injectable, thermosensitive and multicompartment hydrogel for simultaneous encapsulation and independent release of a drug cocktail as an effective combination therapy platform

Pages 57-66; Weiwei Wang, Huijuan Song, Ju Zhang, Pan Li, Chen Li, Chun Wang, Deling Kong, Qiang Zhao

March 2015: Volume 202

Breaching the skin barrier through temperature modulations

Pages 1-13; Yasser Shahzad, Ruaan Louw, Minja Gerber, Jeanetta du Plessis

Potential of nanotechnology as a delivery platform against tuberculosis: Current research review

Pages 65-75; S. Choudhary, V. Kusum Devi

Sustained drug release by contact lenses for glaucoma treatment—A review

Pages 76-82; I.M. Carvalho, C.S. Marques, R.S. Oliveira, P.B. Coelho, P.C. Costa, D.C. Ferreira

Biomaterial modification of urinary catheters with antimicrobials to give long-term broadspectrum antibiofilm activity

Pages 57-64; Leanne E. Fisher, Andrew L. Hook, Waheed Ashraf, Anfal Yousef, David A. Barrett, David J. Scurr, Xinyong Chen, Emily F. Smith, Michael Fay, Christopher D.J. Parmenter, Richard Parkinson, Roger Bayston

Coating nanocarriers with hyaluronic acid facilitates intravitreal drug delivery for retinal gene therapy

Pages 83-92; Thomas F. Martens, Katrien Remaut, Hendrik Deschout, Johan F.J. Engbersen, Wim E. Hennink, Mies J. van Steenbergen, Jo Demeester, Stefaan C. De Smedt, Kevin Braeckmans

Cell penetrating peptide-mediated transport enables the regulated secretion of accumulated cargoes from mast cells

Pages 108-117; John Howl, Sarah Jones

March 2015: Volume 201

Improving drug delivery to solid tumors: Priming the tumor microenvironment

Pages 78-89; Iftikhar Ali Khawar, Jung Ho Kim, Hyo-Jeong Kuh

Cell penetrating peptides improve tumor delivery of cargos through neuropilin-1-dependent extravasation

Pages 14-21; Tetsuya Kadonosono, Akihiro Yamano, Toshiki Goto, Takuya Tsubaki, Mizuho Niibori, Takahiro Kuchimaru, Shinae Kizaka-Kondoh

Mechanistic profiling of the siRNA delivery dynamics of lipid–polymer hybrid nanoparticles

Pages 22-31; Stefano Colombo, Dongmei Cun, Katrien Remaut, Matt Bunker, Jianxin Zhang, Birte Martin-Bertelsen, Anan Yaghmur, Kevin Braeckmans, Hanne M. Nielsen, Camilla Foged

Treatment of neurological disorders by introducing mRNA in vivo using polyplex nanomicelles

Pages 41-48; Miyuki Baba, Keiji Itaka, Kenji Kondo, Tatsuya Yamasoba, Kazunori Kataoka

February 2015: Volume 200

Nanomedicine in cancer therapy: Challenges, opportunities, and clinical applications

Pages 138-157; Andreas Wicki, Dominik Witzigmann, Vimalkumar Balasubramanian, Jörg Huwyler

Cationic micelle delivery of Trp2 peptide for efficient lymphatic draining and enhanced cytotoxic T-lymphocyte responses

Pages 1-12; Qin Zeng, Hao Jiang, Ting Wang, Zhirong Zhang, Tao Gong, Xun Sun

In vivo delivery of siRNA to the brain by carbosilane dendrimer

Pages 60-70; Mª Jesús Serramía, Susana Álvarez, Elena Fuentes-Paniagua, Maria Isabel Clemente, Javier Sánchez-Nieves, Rafael Gómez, Javier de la Mata, Mª Ángeles Muñoz-Fernández

Light-responsive nanoparticle depot to control release of a small molecule angiogenesis inhibitor in the posterior segment of the eye

Pages 71-77; Viet Anh Nguyen Huu, Jing Luo, Jie Zhu, Jing Zhu, Sherrina Patel, Alexander Boone, Enas Mahmoud, Cathryn McFearin, Jason Olejniczak, Caroline de Gracia Lux, Jacques Lux, Nadezda Fomina, Michelle Huynh, Kang Zhang, Adah Almutairi

Tumor-penetrating peptide fused EGFR single-domain antibody enhances cancer drug penetration into 3D multicellular spheroids and facilitates effective gastric cancer therapy

Pages 188-200; Huizi Sha, Zhengyun Zou, Kai Xin, Xinyu Bian, Xueting Cai, Wuguang Lu, Jiao Chen, Gang Chen, Leaf Huang, Andrew M. Blair, Peng Cao, Baorui Liu

Bioreducible core-crosslinked hyaluronic acid micelle for targeted cancer therapy

Pages 158-166; Hwa Seung Han, Ki Young Choi, Hyewon Ko, Jueun Jeon, G. Saravanakumar, Yung Doug Suh, Doo Sung Lee, Jae Hyung Park

February 2015: Volume 199

Tissue penetration of bacteria into quiescent regions of tumors

Page 198; Kinam Park

Amphiphilic poly(amino acid) based micelles applied to drug delivery: The in vitro and in vivo challenges and the corresponding potential strategies

Pages 84-97; Helin Xu, Qing Yao, Cuifang Cai, Jinxin Gou, Yu Zhang, Haijun Zhong, Xing Tang

Peptides as skin penetration enhancers: Mechanisms of action

Pages 168-178; Sunny Kumar, Michael Zakrewsky, Ming Chen, Stefano Menegatti, John A. Muraski, Samir Mitragotri

Monocyte-mediated delivery of polymeric backpacks to inflamed tissues: a generalized strategy to deliver drugs to treat inflammation

Pages 29-36; Aaron C. Anselmo, Jonathan B. Gilbert, Sunny Kumar, Vivek Gupta, Robert E. Cohen, Michael F. Rubner, Samir Mitragotri

January 2015: Volume 198

Bacteria responsive antibacterial surfaces for indwelling device infections

Pages 18-25; Christian Traba, Jun F. Liang

Polymer-doxycycline conjugates as fibril disrupters: An approach towards the treatment of a rare amyloidotic disease

Pages 80-90; Inmaculada Conejos-Sánchez, Isabel Cardoso, Marta Oteo-Vives, Eduardo Romero-Sanz, Alison Paul, Amparo Ruiz Sauri, Miguel A. Morcillo, Maria J. Saraiva, María J. Vicent

January 2015: Volume 197

Brain delivery of insulin boosted by intranasal coadministration with cell-penetrating peptides

Pages 105-110; Noriyasu Kamei, Mariko Takeda-Morishita

Intrathecal injection of a therapeutic gene-containing polyplex to treat spinal cord injury

Pages 1-9; Kentaro Hayakawa, Satoshi Uchida, Toru Ogata, Sakae Tanaka, Kazunori Kataoka, Keiji Itaka

December 2014: Volume 196

Rhythmomimetic Drug Delivery

Page 394; Kinam Park

Fibrin as a delivery system in wound healing tissue engineering applications

Pages 1-8; D. Whelan, N.M. Caplice, A.J.P. Clover

Targeting of gastrointestinal tract for amended delivery of protein/peptide therapeutics: Strategies and industrial perspectives

Pages 168-183; Vivek K. Pawar, Jaya Gopal Meher, Yuvraj Singh, Mohini Chaurasia, B. Surendar Reddy, Manish K. Chourasia

Implants for drug delivery to the posterior segment of the eye: A focus on stimuli-responsive and tunable release systems

Pages 208-221; M. Naveed Yasin, Darren Svirskis, Ali Seyfoddin, Ilva D. Rupenthal

Drug delivery in aortic valve tissue engineering

Pages 307-323; Soumen Jana, Robert D. Simari, Daniel B. Spoon, Amir Lerman

A biomimetic approach to active self-microencapsulation of proteins in PLGA

Pages 60-70; Ronak B. Shah, Steven P. Schwendeman

Ionically cross-linkable hyaluronate-based hydrogels for injectable cell delivery

Pages 146-153; Honghyun Park, Eun Kyung Woo, Kuen Yong Lee

In vivo gene silencing following non-invasive siRNA delivery into the skin using a novel topical formulation

Pages 355-362; Vikas Hegde, Robyn P. Hickerson, Sitheswaran Nainamalai, Paul A. Campbell, Frances J.D. Smith, W.H. Irwin McLean, Deena M. Leslie Pedrioli

Nano-engineered mesenchymal stem cells as targeted therapeutic carriers

Pages 243-251; Tanmoy Sadhukha, Timothy D. O'Brien, Swayam Prabha

December 2014: Volume 195

Intercalating quaternary nicotinamide-based poly(amido amine)s for gene delivery

Pages 11-20; L.J. van der Aa, P. Vader, G. Storm, R.M. Schiffelers, J.F.J. Engbersen

Probing the size limit for nanomedicine penetration into Burkholderia multivorans and Pseudomonas aeruginosa biofilms

Pages 21-28; Katrien Forier, Anne-Sophie Messiaen, Koen Raemdonck, Hans Nelis, Stefaan De Smedt, Jo Demeester, Tom Coenye, Kevin Braeckmans

Current issues of RNAi therapeutics delivery and development

Pages 49-54; D. Haussecker

Distal phenylalanine modification for enhancing cellular delivery of fluorophores, proteins and quantum dots by cell penetrating peptides

Pages 55-62; E.J. Sayers, K. Cleal, N.G. Eissa, P. Watson, A.T. Jones

Effect of shear on physicochemical properties of matrix metalloproteinase responsive silk-elastinlike hydrogels

Pages 92-98; Robert Price, Azadeh Poursaid, Joseph Cappello, Hamidreza Ghandehari

Nanoporous polyelectrolyte vaccine microcarriers. A formulation platform for enhancing humoral and cellular immune responses

Pages 99-109; Stefaan De Koker, Kaat Fierens, Marijke Dierendonck, Riet De Rycke, Bart N. Lambrecht, Johan Grooten, Jean Paul Remon, Bruno G. De Geest

Functional polymers of gene delivery for treatment of myocardial infarct

Pages 110-119; Young-Wook Won, David A. Bull, Sung Wan Kim

Thiomers — From bench to market

Pages 120-129; Sonja Bonengel, Andreas Bernkop-Schnürch

Decationized polyplexes as stable and safe carrier systems for improved biodistribution in systemic gene therapy

Pages 162-175; Luís Novo, Larissa Y. Rizzo, Susanne K. Golombek, George R. Dakwar, Bo Lou, Katrien Remaut, Enrico Mastrobattista, Cornelus F. van Nostrum, Wilhelm Jahnen-Dechent, Fabian Kiessling, Kevin Braeckmans, Twan Lammers, Wim E. Hennink

November 2014: Volume 194

Stimuli-responsive nanomaterials for therapeutic protein delivery

Pages 1-19; Yue Lu, Wujin Sun, Zhen Gu

A survey on “Trojan Horse” peptides: Opportunities, issues and controlled entry to “Troy”Review Article

Pages 53-70; Nian-Qiu Shi, Xian-Rong Qi, Bai Xiang, Yong Zhang

Rationale employment of cell culture versus conventional techniques in pharmaceutical appraisal of nanocarriers

Pages 92-102; Manal A. Elsheikh, Yosra S.R. Elnaggar, Ossama Y. Abdallah

Recent advances of resveratrol in nanostructured based delivery systems and in the management of HIV/AIDS

Pages 178-188; Gurinder Singh, Roopa S. Pai

Nanocarrier mediated delivery of siRNA/miRNA in combination with chemotherapeutic agents for cancer therapy: Current progress and advances

Pages 238-256; Nishant S. Gandhi, Rakesh K. Tekade, Mahavir B. Chougule

Formulation and delivery of anti-HIV rectal microbicides: Advances and challenges

Pages 278-294; Rute Nunes, Bruno Sarmento, José das Neves

Pollen grains for oral vaccination

Pages 45-52; Shashwati U. Atwe, Yunzhe Ma, Harvinder Singh Gill

Fibroblast-derived matrix (FDM) as a novel vascular endothelial growth factor delivery platform

Pages 122-129; Ping Du, Mintai P. Hwang, Yong Kwan Noh, Ramesh Subbiah, In Gul Kim, Soon Eon Bae, Kwideok Park

Combination of antibody targeting and PTD-mediated intracellular toxin delivery for colorectal cancer therapy

Pages 197-210; Meong Cheol Shin, Jian Zhang, Kyoung Ah Min, Kyuri Lee, Cheol Moon, Joseph P. Balthasar, Victor C. Yang

Delivery of antisense oligonucleotides using poly(alkylene oxide)–poly(propylacrylic acid) graft copolymers in conjunction with cationic liposomes

Pages 103-112; Lavanya Y. Peddada, Olga B. Garbuzenko, David I. Devore, Tamara Minko, Charles M. Roth

PLGA nanoparticles loaded with host defense peptide LL37 promote wound healing

Pages 138-147; Kiran Kumar Chereddy, Charles-Henry Her, Michela Comune, Claudia Moia, Alessandra Lopes, Paolo E. Porporato, Julie Vanacker, Martin C. Lam, Lars Steinstraesser, Pierre Sonveaux, Huijun Zhu, Lino S. Ferreira, Gaëlle Vandermeulen, Véronique Préat

Poly(ethylene glycol) (PEG)-lactic acid nanocarrier-based degradable hydrogels for restoring the vaginal microenvironment

Pages 301-309; Sujata Sundara Rajan, Yevgeniy Turovskiy, Yashveer Singh, Michael L. Chikindas, Patrick J. Sinko