ACS Nano

April 2021: Volume 15, Issue 4

Janus Nanoparticles: From Fabrication to (Bio)Applications

Xuan Zhang, Qinrui Fu, Hongwei Duan*, Jibin Song*, and Huanghao Yang*

Sequential Release of Small Extracellular Vesicles from Bilayered Thiolated Alginate/Polyethylene Glycol Diacrylate Hydrogels for Scarless Wound Healing

Yifan Shen, Guanzhe Xu, Huanxuan Huang, Kaiyang Wang, Hui Wang, Meidong Lang*, Hong Gao*, and Shichang Zhao*

Healable, Degradable, and Conductive MXene Nanocomposite Hydrogel for Multifunctional Epidermal Sensors

Xiaobin Li, Lingzhang He, Yanfei Li, Mingyuan Chao, Mingkun Li, Pengbo Wan*, and Liqun Zhang

March 2021: Volume 15, Issue 3

Sculpting Enzyme-Generated Giant Polymer Brushes

Jessica L. Faubel, Wenbin Wei, and Jennifer E. Curtis*

Ultrafast Directional Janus Pt–Mesoporous Silica Nanomotors for Smart Drug Delivery

Paula Díez, Elena Lucena-Sánchez, Andrea Escudero, Antoni Llopis-Lorente, Reynaldo Villalonga, and Ramón Martínez-Máñez*

Superelastic Ti3C2Tx MXene-Based Hybrid Aerogels for Compression-Resilient Devices

Degang Jiang, Jizhen Zhang, Si Qin, Zhiyu Wang, Ken Aldren S. Usman, Dylan Hegh, Jingquan Liu, Weiwei Lei, and Joselito M. Razal*

Protein Nanofibrils and Their Hydrogel Formation with Metal Ions

Xinchen Ye, Antonio J. Capezza, Xiong Xiao, Christofer Lendel, Mikael S. Hedenqvist, Vadim G. Kessler, and Richard T. Olsson*

Molecular Weight Dependent Morphological Transitions of Bottlebrush Block Copolymer Particles: Experiments and Simulations

Eun Ji Kim, Jaeman J. Shin, Taeyang Do, Gue Seon Lee, Juhae Park, Vikarm Thapar, Jinwoong Choi, Joona Bang, Gi-Ra Yi, Su-Mi Hur*, Jeung Gon Kim* and Bumjoon J. Kim*

February 2021: Volume 15, Issue 2

Ti3C2Tx MXene-Activated Fast Gelation of Stretchable and Self-Healing Hydrogels: A Molecular Approach

Gang Ge, Yi-Zhou Zhang, Wenli Zhang, Wei Yuan, Jehad K. El-Demellawi, Peng Zhang, Enzo Di Fabrizio, Xiaochen Dong*, and Husam N. Alshareef*

Electronic Tuning of Monolayer Graphene with Polymeric “Zwitterists”

James Nicolas Pagaduan, Nicholas Hight-Huf, Avdhoot Datar, Yehiel Nagar, Michael Barnes, Doron Naveh, Ashwin Ramasubramaniam*, Reika Katsumata*, and Todd Emrick*

Dual Channel Microfluidics for Mimicking the Blood–Brain Barrier

Boris Buchroithner, Sandra Mayr, Fabian Hauser, Eleni Priglinger, Herbert Stangl, Ana Raquel Santa-Maria, Maria A. Deli, Andras Der, Thomas A. Klar, Markus Axmann, Dmitry Sivun, Mario Mairhofer, and Jaroslaw Jacak*

Bridging the Synthesis Gap: Ionic Liquids Enable Solvent-Mediated Reaction in Vapor-Phase Deposition

Jingwei Shi and Stacey F. Bent*

January 2021: Volume 15, Issue 1

Genome-in-a-Box: Building a Chromosome from the Bottom Up

Anthony Birnie and Cees Dekker*

Magnetic Nanocomposite Hydrogels for Tissue Engineering: Design Concepts and Remote Actuation Strategies to Control Cell Fate

Alberto Pardo, Manuel Gómez-Florit, Silvia Barbosa, Pablo Taboada, Rui M. A. Domingues*, and Manuela E. Gomes*

Coatable and Resistance-Proof Ionic Liquid for Pathogen Eradication

Marcelo D. T. Torres, Sahag Voskian, Paul Brown, Andong Liu, Timothy K. Lu, T. Alan Hatton, and Cesar de la Fuente-Nunez*

Confined Crack Propagation in MoS2 Monolayers by Creating Atomic Vacancies

Yolanda Manzanares-Negro, Guillermo López-Polín, Kazunori Fujisawa, Tianyi Zhang, Fu Zhang, Ethan Kahn, Néstor Perea-López, Mauricio Terrones, Julio Gómez-Herrero, and Cristina Gómez-Navarro*

Biomimetic Virus-Like Particles as Severe Acute Respiratory Syndrome Coronavirus 2 Diagnostic Tools

Soo Khim Chan, Pinyi Du, Caroline Ignacio, Sanjay Mehta, Isabel G. Newton, and Nicole F. Steinmetz*

Dopamine-Triggered Hydrogels with High Transparency, Self-Adhesion, and Thermoresponse as Skinlike Sensors

Chao Zhang, Yongsen Zhou, Haijie Han, Huanxi Zheng, Wanghuai Xu, and Zuankai Wang*

December 2020: Volume 14, Issue 12

Airborne Transmission of COVID-19: Aerosol Dispersion, Lung Deposition, and Virus-Receptor Interactions

Yi Y. Zuo*, William E. Uspal*, and Tao Wei*

Conductive Hydrogel for a Photothermal-Responsive Stretchable Artificial Nerve and Coalescing with a Damaged Peripheral Nerve

Mei Dong, Bo Shi, Dun Liu, Jia-Hao Liu, Di Zhao, Zheng-Hang Yu, Xiao-Quan Shen, Jia-Min Gan, Ben-long Shi, Yong Qiu, Chang-Chun Wang*, Ze-Zhang Zhu*, and Qun-Dong Shen*

Highly Elastic Hydrated Cellulosic Materials with Durable Compressibility and Tunable Conductivity

Chaoji Chen, Jianwei Song, Jian Cheng, Zhenqian Pang, Wentao Gan, Gegu Chen, Yudi Kuang, Hao Huang, Upamanyu Ray, Teng Li*, and Liangbing Hu*

Combined Catalysis for Engineering Bioinspired, Lignin-Based, Long-Lasting, Adhesive, Self-Mending, Antimicrobial Hydrogels

Samson Afewerki*, Xichi Wang, Guillermo U. Ruiz-Esparza, Cheuk-Wai Tai, Xueying Kong, Shengyang Zhou, Ken Welch, Ping Huang, Rhodel Bengtsson, Chao Xu*, and Maria Strømme*

Programmable Anisotropy and Percolation in Supramolecular Patchy Particle Gels

Jake Song, Mehedi H. Rizvi, Brian B. Lynch, Jan Ilavsky, David Mankus, Joseph B. Tracy, Gareth H. McKinley*, and Niels Holten-Andersen*

Confinement and Processing Can Alter the Morphology and Periodicity of Bottlebrush Block Copolymers in Thin Films

Daniel F. Sunday*, Moshe Dolejsi, Alice B. Chang, Lee J. Richter, Ruipeng Li, R. Joseph Kline, Paul F. Nealey, and Robert H. Grubbs

November 2020: Volume 14, Issue 11

Molecular Transport through a Biomimetic DNA Channel on Live Cell Membranes

Cheng Lv,, Xiyao Gu, Haowen Li, Yumeng Zhao, Donglei Yang, Weifeng Yu*, Da Han*, Juan Li, and Weihong Tan*

Large-Scale Spinning Approach to Engineering Knittable Hydrogel Fiber for Soft Robots

Xiangyu Duan, Jingyi Yu, Yaxun Zhu, Zhiqiang Zheng, Qihua Liao, Yukun Xiao, Yuanyuan Li, Zipan He, Yang Zhao*, Huaping Wang, and Liangti Qu

Flash Graphene from Plastic Waste

Wala A. Algozeeb, Paul E. Savas, Duy Xuan Luong, Weiyin Chen, Carter Kittrell, Mahesh Bhat, Rouzbeh Shahsavari, and James M. Tour

Nanosensor-Based Flexible Electronic Assisted with Light Fidelity Communicating Technology for Volatolomics-Based Telemedicine

Han Jin*, Junkan Yu, Shujing Lin, Shan Gao, Hao Yang, Hossam Haick, Changzhou Hua, Shengwei Deng, Tingqiang Yang, Yueli Liu, Wenfeng Shen, Xin Zhang, Xiaowei Zhang, Shan Shan, Tao Ren, Liwei Wang, Waifung Cheung, Wanlung Kam, Jianmin Miao, Di Chen, and Daxiang Cui*

October 2020: Volume 14, Issue 10

Conductive Hydrogel for a Photothermal-Responsive Stretchable Artificial Nerve and Coalescing with a Damaged Peripheral Nerve

Mei Dong, Bo Shi, Dun Liu, Jia-Hao Liu, Di Zhao, Zheng-Hang Yu, Xiao-Quan Shen, Jia-Min Gan, Ben-long Shi, Yong Qiu, Chang-Chun Wang*, Ze-Zhang Zhu*, and Qun-Dong Shen*ACS Nano

COVID-19 Vaccine Frontrunners and Their Nanotechnology Design

Young Hun Chung, Veronique Beiss, Steven N. Fiering*, and Nicole F. Steinmetz*

Microfluidic Cell Stretching for Highly Effective Gene Delivery into Hard-to-Transfect Primary Cells

Jeongsoo Hur, Inae Park, Kyung Min Lim, Junsang Doh, Ssang-Goo Cho, and Aram J. Chung*

Lateral Ordering in Nanoscale Ionic Liquid Films between Charged Surfaces Enhances Lubricity

Silvia Di Lecce*, Alexei A. Kornyshev, Michael Urbakh, and Fernando Bresme*

Reconfigurable Transitions between One- and Two-Dimensional Structures with Bifunctional DNA-Coated Janus Colloids

Joon Suk Oh, Gi-Ra Yi*, and David J. Pine*

September 2020: Volume 14, Issue 9

Enhanced Cancer DNA Vaccine via Direct Transfection to Host Dendritic Cells Recruited in Injectable Scaffolds

Thanh Loc Nguyen, Yue Yin, Youngjin Choi, Ji Hoon Jeong*, and Jaeyun Kim*

An Ingestible Self-Polymerizing System for Targeted Sampling of Gut Microbiota and Biomarkers

Lu Chen, Lina Gruzinskyte, Steffen Lynge Jørgensen, Anja Boisen, and Sarvesh Kumar Srivastava*

Graphene Oxide Nanoribbon Hydrogel: Viscoelastic Behavior and Use as a Molecular Separation Membrane

Yunkyu Choi, Sung-Soo Kim, Ji Hoon Kim, Junhyeok Kang, Eunji Choi, Seung Eun Choi, Jeong Pil Kim, Ohchan Kwon, and Dae Woo Kim*

August 2020: Volume 14, Issue 8

DNA Strands Trigger the Intracellular Release of Drugs from Mucin-Based Nanocarriers

Ceren Kimna, Theresa Monika Lutz, Hongji Yan, Jian Song, Thomas Crouzier, and Oliver Lieleg*

Collagen-Inspired Helical Peptide Coassembly Forms a Rigid Hydrogel with Twisted Polyproline II Architecture

Moumita Ghosh, Santu Bera, Sarah Schiffmann, Linda J. W. Shimon, and Lihi Adler-Abramovich*

July 2020: Volume 14, Issue 7

Biomimetic Rebuilding of Multifunctional Red Blood Cells: Modular Design Using Functional Component

• Jimin Guo, Jacob Ongudi Agola, Rita Serda, Stefan Franco, Qi Lei, Lu Wang, Joshua Minster, Jonas G. Croissant, Kimberly S. Butler, Wei Zhu*, and C. Jeffrey Brinker*

Multifunctional Supramolecular Hydrogel for Prevention of Epidural Adhesion after Laminectomy

• Yan Wang, Lanlan Li, Yongchang Ma, Yong Tang, Yang Zhao, Zimeng Li, Wendan Pu, Bo Huang, Xuan Wen, Xiaojuan Cao, Jiafei Chen, Wei Chen, Yue Zhou*, and Jianxiang Zhang*

Highly Robust and Self-Powered Electronic Skin Based on Tough Conductive Self-Healing Elastomer

• Xiaochen Xun, Zheng Zhang, Xuan Zhao, Bin Zhao, Fangfang Gao, Zhuo Kang, Qingliang Liao, and Yue Zhang*

Remotely Triggered Liquefaction of Hydrogel Materials

Søren L. Pedersen, Tin H. Huynh, Philipp Pöschko, Anne Sofi Fruergaard, Morten T. Jarlstad Olesen, Yaqing Chen, Henrik Birkedal, Guruprakash Subbiahdoss, Erik Reimhult, Jan Thøgersen, and Alexander N. Zelikin*

June 2020: Volume 14, Issue 6

Emerging Implantable Energy Harvesters and Self-Powered Implantable Medical Electronics

Dongjie Jiang, Bojing Shi, Han Ouyang, Yubo Fan, Zhong Lin Wang, and Zhou Li

Polyglycerol Grafting Shields Nanoparticles from Protein Corona Formation to Avoid Macrophage Uptake

Yajuan Zou, Shinji Ito, Fumi Yoshino, Yuta Suzuki, Li Zhao, and Naoki Komatsu

May 2020: Volume 14, Issue 5

Big Is Beautiful: Enhanced saRNA Delivery and Immunogenicity by a Higher Molecular Weight, Bioreducible, Cationic Polymer

Anna K. Blakney, Yunqing Zhu, Paul F. McKay, Clément R. Bouton, Jonathan Yeow, Jiaqing Tang, Kai Hu, Karnyart Samnuan, Christopher L. Grigsby, Robin J. Shattock*, and Molly M. Stevens*

Supramolecular Assemblies of Heterogeneous Mesoporous Silica Nanoparticles to Co-deliver Antimicrobial Peptides and Antibiotics for Synergistic Eradication of Pathogenic Biofilms

Qilin Yu, Tian Deng, Fang-Chu Lin, Bing Zhang, and Jeffrey I. Zink

April 2020: Volume 14, Issue 4

Zinc-Finger-Mediated Labeling Reveals the Stoichiometry of Membrane Proteins

Changsheng Chen and Maximilian H. Ulbrich*

Endocytosis of Extracellular Vesicles and Release of Their Cargo from Endosomes

Bhagyashree S. Joshi, Marit A. de Beer, Ben N. G. Giepmans, and Inge S. Zuhorn*

Mechanistic Understanding of the Biological Responses to Polymeric Nanoparticles

Kenry, Trifanny Yeo, Purnima Naresh Manghnani, Eshu Middha, Yutong Pan, Huan Chen, Chwee Teck Lim, and Bin Liu*

Nanoparticle Uptake in a Spontaneous andImmuno competent Woodchuck Liver Cancer Model

Lewis Y. Liu, Xue-Zhong Ma, Ben Ouyang, Danielle P. Ings, Sagar Marwah, Jeff Liu, Annie Y. Chen, Rahul Gupta, Justin Manuel, Xu-Chun Chen, Blair K. Gage, Iulia Cirlan, Nicholas Khuu, Sai Chung, Damra Camat, Michael Cheng, Manmeet Sekhon, Kyryl Zagorovsky, Mohamed A. Abdou Mohamed, Cornelia Thoeni, Jawairia Atif, Juan Echeverri, Dagmar Kollmann, Sandra Fischer, Gary D. Bader, Warren C. W. Chan, Tomasz I. Michalak*, Ian D. McGilvray*, and Sonya A. MacParland*

March 2020: Volume 14, Issue 3

•Nanocarriers for the Delivery of Medical, Veterinary, and Agricultural Active Ingredients.

Paul L. Chariou, Oscar A. Ortega-Rivera, Nicole F. Steinmetz*

•Protein Binding Affinity of Polymeric Nanoparticles as a Direct Indicator of Their Pharamacokinetics

Zhi-Ting Cao, Li-Qin Gan, Wei Jiang, Ji-Long Wang, Hou-Bing Zhang, Yue Zhang, Yucai Wang, Xianzhu Yang, Menghua Xiong*, Jun Wang*

•Cell-Penetrating Nanoparticles Activate the Inflammasome to Enhance Antibody Production by Targeting Microtubule-Associated Protein 1-Light Chain 3 for Degradation

• Motao Zhu, Libo Du, Ruifang Zhao, Helen Y. Wang, Yuliang Zhao, Guangjun Nie*, Rong-Fu Wang*

February 2020: Volume 14, Issue 2

Biomimetic Tactile Sensors Based on Nanomaterials

Yongjun LeeJong-Hyun Ahn*

A Self-Assembled α-Synuclein Nanoscavenger for Parkinson’s Disease

Jingyi LiuChao LiuJinfeng ZhangYunming ZhangKeyin LiuJu-Xian SongSravan Gopalkrishnashetty SreenivasmurthyZiying WangYesi ShiChengchao ChuYang ZhangCaisheng WuXianhua DengXingyang LiuJing SongRongqiang ZhuangShuqiong HuangPengfei ZhangMin Li*Lei Wen*Yun wu ZhangGang Liu*

Protein@Inorganic Nanodumpling System for High-Loading Protein Delivery with Activatable Fluorescence and Magnetic Resonance Bimodal Imaging Capabilities

Xiaohua ZhuRui TangShigong WangXiaoye ChenJiajun HuChunyang LeiYan HuangHonghui WangZhou Nie*Shouzhuo Yao

January 2020: Volume 14, Issue 1

Muscle-Inspired Self-Healing Hydrogels for Strain and Temperature Sensor

Gang GeYao LuXinyu QuWen ZhaoYanfang RenWenjun WangQian Wang*Wei HuangXiaochen Dong*

Regulation of Cell Uptake and Cytotoxicity by Nanoparticle Core under the Controlled Shape, Size, and Surface Chemistries

Xue BaiShenqing WangXiliang YanHongyu ZhouJinhua ZhanSijin LiuVirender K. SharmaGuibin JiangHao ZhuBing Yan*

Glucose-Responsive Nanoparticles for Rapid and Extended Self-Regulated Insulin Delivery

Lisa R. VolpattiMorgan A. MatrangaAbel B. CortinasDerfogail DelcassianKevin B. DanielRobert LangerDaniel G. Anderson*

December 2019: Volume 13, Issue 12

Nanomedicines Lost in Translation

Keegan GuidolinGang Zheng*

Resolving Single-Nanoconstruct Dynamics during Targeting and Nontargeting Live-Cell Membrane Interactions

Debanjan BhowmikKayla S. B. CulverTingting LiuTeri W. Odom*

Dual Corona Vesicles with Intrinsic Antibacterial and Enhanced Antibiotic Delivery Capabilities for Effective Treatment of Biofilm-Induced Periodontitis

Yuejing XiYue WangJingyi GaoYufen XiaoJianzhong Du*

Exploiting the Lymph-Node-Amplifying Effect for Potent Systemic and Gastrointestinal Immune Responses via Polymer/Lipid Nanoparticles

Yiqun DuYufei XiaYongjuan ZouYuning HuJiaqi FuJie Wu*Xiao-Dong Gao*Guanghui Ma*

Tumor-Derived Extracellular Vesicles Breach the Intact Blood–Brain Barrier via Transcytosis

Golnaz MoradChristopher V. CarmanElliott J. HagedornJulie R. PerlinLeonard I. ZonNur MustafaogluTae-Eun ParkDonald E. IngberCassandra C. DaisyMarsha A. Moses*

Label-Free Analysis of Protein Aggregation and Phase Behavior

Zenon ToprakciogluPavankumar ChallaCatherine XuTuomas P. J. Knowles*

November 2019: Volume 13, Issue 11

Reshaping Prostate Tumor Microenvironment To Suppress Metastasis via Cancer-Associated Fibroblast Inactivation with Peptide-Assembly-Based Nanosystem

Jiayan LangXiao ZhaoYingqiu QiYinlong ZhangXuexiang HanYanping DingJiajing GuanTianjiao Ji*Ying Zhao*Guangjun Nie*

Outer-Frame-Degradable Nanovehicles Featuring Near-Infrared Dual Luminescence for in Vivo Tracking of Protein Delivery in Cancer Therapy

Fenfen ZhengChen WangTiantian MengYuqian ZhangPenghui ZhangQi ShenYuchao ZhangJunfeng ZhangJianxin LiQianhao Min*Jiangning Chen*Jun-Jie Zhu*

Nonequilibrium Reshaping of Polymersomes via Polymer Addition

Yongjun MenWei LiYingfeng TuFei PengGeert-Jan A. JanssenRoeland J. M. NolteDaniela A. Wilson*

October 2019: Volume 13, Issue 10

Tuning Organelle Specificity and Photodynamic Therapy Efficiency by Molecular Function Design

Zhiyang Liu, Hang Zou, Zheng Zhao, Pengfei Zhang, Guo-Gang Shan, Ryan T. K. Kwok, Jacky W. Y. Lam, Lei Zheng*, Ben Zhong Tang*

September 2019: Volume 13, Issue 9

Kinetic Control in Assembly of Plasmid DNA/Polycation Complex Nanoparticles

Yizong HuZhiyu HeYue HaoLike GongMarion PangGregory P. HowardHye-Hyun AhnMary BrummetKuntao ChenHeng-wen LiuXiyu KeJinchang ZhuCaleb F. AndersonHonggang CuiChristopher G. UllmanChristine A. CarringtonMartin G. PomperJung-Hee SeoRajat MittalIl Minn*Hai-Quan Mao*

Intracellular Photothermal Delivery for Suspension Cells Using Sharp Nanoscale Tips in Microwells

Tianxing ManXiongfeng ZhuYu Ting ChowEmma R. DawsonXimiao WenAlexander N. PatanananTingyi Leo LiuChuanzhen ZhaoCong WuJason S. HongPei-Shan ChungDaniel L. ClemensBai-Yu LeePaul S. WeissMichael A. TeitellPei-Yu Chiou*

August 2019: Volume 13, Issue 8

Reversible Click Chemistry for Ultrafast and Quantitative Formation of Protein–Polymer Nanoassembly and Intracellular Protein Delivery

Bin LiuMargareta Ianosi-IrimieS. Thayumanavan*

July 2019: Volume 13, Issue 7

Tailoring the Shape and Size of Artificial Cells

Ahanjit BhattacharyaNeal K. Devaraj*

Role of Nanoparticle Mechanical Properties in Cancer Drug Delivery

Yue HuiXin YiFei HouDavid WibowoFan ZhangDongyuan Zhao*Huajian Gao*Chun-Xia Zhao*

Mussel-Inspired Self-Healing Metallopolymers for Silicon Nanoparticle Anodes

You Kyeong JeongJang Wook Choi*

Extending Single-Molecule Förster Resonance Energy Transfer (FRET) Range beyond 10 Nanometers in Zero-Mode Waveguides

Mikhail BaibakovSatyajit PatraJean-Benoît ClaudeAntonin MoreauJulien LumeauJérôme Wenger*

June 2019: Volume 13, Issue 6

Correction to Pathogen-Specific Polymeric Antimicrobials with Significant Membrane Disruption and Enhanced Photodynamic Damage To Inhibit Highly Opportunistic Bacteria

Fengfeng XiaoBing CaoCongyu WangXujuan GuoMengge LiDa XingXianglong Hu*

May 2019: Volume 13, Issue 5

Experiments and Simulations of Complex Sugar-Based Coil−Brush Block Polymer Nanoassemblies in Aqueous Solution

Mei DongMichiel G. WesselsJee Young LeeLu SuHai WangRachel A. LetteriYue SongYen-Nan LinYingchao ChenRichen LiDarrin J. Pochan*Arthi Jayaraman*Karen L. Wooley*

Self-Assembly of Artificial Sweetener Aspartame Yields Amyloid-like Cytotoxic Nanostructures

Bibin Gnanadhason AnandKailash Prasad PrajapatiKriti DubeyNaseem AhamadDolat Singh ShekhawatPramod Chandra RathGeorge Kodimattam JosephKarunakar Kar*

April 2019: Volume 13, Issue 4

Lipid-Based DNA Therapeutics: Hallmarks of Non-Viral Gene Delivery

Jonas BuckPhilip GrossenPieter R. CullisJörg Huwyler*Dominik Witzigmann*

Crab-on-a-Tree: All Biorenewable, Optical and Radio Frequency Transparent Barrier Nanocoating for Food Packaging

Taehyung KimThang Hong TranSung Yeon HwangJeyoung ParkDongyeop X. Oh*Byeong-Su Kim*

Liquid-Behaviors-Assisted Fabrication of Multidimensional Birefringent Materials from Dynamic Hybrid Hydrogels

Heqin HuangXiaojie WangJinchao YuYe ChenHong JiYumei ZhangFlorian RehfeldtYong WangKai Zhang*

Coordinative Binding of Polymers to Metal–Organic Framework Nanoparticles for Control of Interactions at the Biointerface

Andreas ZimpelNader Al DanafBenjamin SteinbornJasmin KuhnMiriam HöhnTobias BauerPatrick HirschleWaldemar SchrimpfHanna EngelkeErnst WagnerMatthias BarzDon C. LambUlrich Lächelt*Stefan Wuttke*

Golgi Apparatus-Targeted Chondroitin-Modified Nanomicelles Suppress Hepatic Stellate Cell Activation for the Management of Liver Fibrosis

Jingwen LuoPei ZhangTing ZhaoMengdi JiaPeng YinWenhao LiZhi-Rong ZhangYao FuTao Gong*

Contrasting Chemistry of Block Copolymer Films Controls the Dynamics of Protein Self-Assembly at the Nanoscale

Bart StelIlja GunkelXiaodan GuThomas P. Russell*James J. De Yoreo*Magalí Lingenfelder*

March 2019: Volume 13, Issue 3

Assessing Pair Interaction Potentials of Nanoparticles on Liquid Interfaces

Paul Y. Kim, Yige Gao, Yu Chai, Paul D. Ashby, Alexander E. Ribbe, David A. Hoagland, and Thomas P. Russell

February 2019

Bio-Inspired Robust Membranes Nanoengineered from Interpenetrating Polymer Networks of Polybenzimidazole/Polydopamine

Dan Zhao, Jeong F. Kim, Gergo Ignacz, Peter Pogany, Young Moo Lee, and Gyorgy Szekely

Assessing the Thickness–Permeation Paradigm in Nanoporous Membranes

Jakob Buchheim, Karl-Philipp Schlichting, Roman M. Wyss, and Hyung Gyu Park

Phototheranostics: Active Targeting of Orthotopic Glioma Using Biomimetic Proteolipid Nanoparticles

Yali Jia, Xiaobing Wang, Dehong Hu, Pan Wang, Quanhong Liu, Xuanjun Zhang, Jingying Jiang, Xin Liu, Zonghai Sheng, Bin Liu, and Hairong Zheng

Localized Nanoscale Heating Leads to Ultrafast Hydrogel Volume-Phase Transition

Jing Zhao, Hanquan Su, Gregory E. Vansuch, Zheng Liu, Khalid Salaita, and R. Brian Dyer

Noncontact Imaging of Ion Dynamics in Polymer Electrolytes with Time-Resolved Electrostatic Force Microscopy

Jeffrey S. Harrison, Dean A. Waldow, Phillip A. Cox, Rajiv Giridharagopal, Marisa Adams, Victoria Richmond, Sevryn Modahl, Megan Longstaff, Rodion Zhuravlev, and David S. Ginger

Single-Cell Photothermal Neuromodulation for Functional Mapping of Neural Networks

Sangjin Yoo, Ji-Ho Park, and Yoonkey Nam

RNA Micelles for the Systemic Delivery of Anti-miRNA for Cancer Targeting and Inhibition without Ligand

Hongran Yin, Hongzhi Wang, Zhefeng Li, Dan Shu, and Peixuan Guo

January 2019

“Waltz” of Cell Membrane-Coated Nanoparticles on Lipid Bilayers: Tracking Single Particle Rotation in Ligand–Receptor Binding

Yanqi Yu, Yuan Gao, and Yan Yu

Beyond the Roles in Biomimetic Chemistry: An Insight into the Intrinsic Catalytic Activity of an Enzyme for Tumor-Selective Phototheranostics

Weitao Yang, Xiudong Shi, Yuxin Shi, Defan Yao, Shizhen Chen, Xin Zhou, and Bingbo Zhang

Mitochondria-Targeted DNA Nanoprobe for Real-Time Imaging and Simultaneous Quantification of Ca2+ and pH in Neurons

Zhichao Liu, Hao Pei, Limin Zhang, and Yang Tian

November 2018

AA′-Stacked Trilayer Hexagonal Boron Nitride Membrane for Proton Exchange Membrane Fuel Cells

Seong In Yoon, Dong-Jun Seo, Gwangwoo Kim, Minsu Kim, Chi-Young Jung, Young-Gi Yoon, Sang Hoon Joo, Tae-Young Kim, and Hyeon Suk Shin

Biomimetic Elastomeric Polypeptide-Based Nanofibrous Matrix for Overcoming Multidrug-Resistant Bacteria and Enhancing Full-Thickness Wound Healing/Skin Regeneration

Yuewei Xi, Juan Ge, Yi Guo, Bo Lei, and Peter X. Ma

Soft Conducting Polymer Hydrogels Cross-Linked and Doped by Tannic Acid for Spinal Cord Injury Repair

Lei Zhou, Lei Fan, Xin Yi, Zhengnan Zhou, Can Liu, Ruming Fu, Cong Dai, Zhengao Wang, Xiuxing Chen, Peng Yu, Dafu Chen, Guoxin Tan, Qiyou Wang, and Chengyun Ning

All-Poly(ionic liquid) Membrane-Derived Porous Carbon Membranes: Scalable Synthesis and Application for Photothermal Conversion in Seawater Desalination

Yue Shao, Zhiping Jiang, Yunjing Zhang, Tongzhou Wang, Peng Zhao, Zhe Zhang, Jiayin Yuan, and Hong Wang

Synthetic Cargo Internalization Receptor System for Nanoparticle Tracking of Individual Cell Populations by Fluorine Magnetic Resonance Imaging

Sebastian Temme, Paul Baran, Pascal Bouvain, Christoph Grapentin, Wolfgang Krämer, Birgit Knebel, Hadi Al-Hasani, Jens Mark Moll, Doreen Floss, Jürgen Schrader, Rolf Schubert, Ulrich Flögel, and Jürgen Scheller

Bioinspired Block Copolymer for Mineralized Nanoporous Membrane

Hui-Jun Zhou, Guan-Wen Yang, Yao-Yao Zhang, Zhi-Kang Xu, and Guang-Peng Wu

Ionic Conductivity in Ionic Liquid Nano Thin Films

Shingo Maruyama, Ida Bagus Hendra Prastiawan, Kaho Toyabe, Yuji Higuchi, Tomoyuki Koganezawa, Momoji Kubo, and Yuji Matsumoto

One-Pot Preparation of Mechanically Robust, Transparent, Highly Conductive, and Memristive Metal–Organic Ultrathin Film

Miriam Moreno-Moreno, Javier Troyano, Pablo Ares, Oscar Castillo, Christian A. Nijhuis, Li Yuan, Pilar Amo-Ochoa, Salomé Delgado, Julio Gómez-Herrero, Félix Zamora, and Cristina Gómez-Navarro

June 2018

Nongenetic Optical Methods for Measuring and Modulating Neuronal Response

John F. Zimmerman, and Bozhi Tian

April 2018

Waterproof and Tailorable Elastic Rechargeable Yarn Zinc Ion Batteries by a Cross-Linked Polyacrylamide Electrolyte

Hongfei Li, Zhuoxin Liu, Guojin Liang, Yang Huang, Yan Huang, Minshen Zhu, Zengxia Pei, Qi Xue, Zijie Tang, Yukun Wang, Baohua Li, and Chunyi Zhi

Control of Oxidation and Spin State in a Single-Molecule Junction

Benjamin W. Heinrich, Christopher Ehlert, Nino Hatter, Lukas Braun, Christian Lotze, Peter Saalfrank, and Katharina J. Franke

Reconfigurable Microfluidic Droplets Stabilized by Nanoparticle Surfactants

Anju Toor, Sean Lamb, Brett A. Helms, and Thomas P. Russell

Ionic Correlations in Random Ionomers

Boran Ma, Trung Dac Nguyen, Victor A. Pryamitsyn, and Monica Olvera de la Cruz

March 2018

Macrophage-Specific in Vivo Gene Editing Using Cationic Lipid-Assisted Polymeric Nanoparticles

Ying-Li Luo, Cong-Fei Xu, Hong-Jun Li, Zhi-Ting Cao, Jing Liu, Ji-Long Wang, Xiao-Jiao Du, Xian-Zhu Yang, Zhen Gu, and Jun Wang

Directed Self-Assembly of Asymmetric Block Copolymers in Thin Films Driven by Uniaxially Aligned Topographic Patterns

Dong-Eun Lee, Jaegeon Ryu, Dongki Hong, Soojin Park, Dong Hyun Lee, and Thomas P. Russell

Repeatable Photodynamic Therapy with Triggered Signaling Pathways of Fibroblast Cell Proliferation and Differentiation To Promote Bacteria-Accompanied Wound Healing

Congyang Mao, Yiming Xiang, Xiangmei Liu, Zhenduo Cui, Xianjin Yang, Zhaoyang Li, Shengli Zhu, Yufeng Zheng, Kelvin Wai Kwok Yeung, and Shuilin Wu

January 2018

Selective Transport through Membranes with Charged Nanochannels Formed by Scalable Self-Assembly of Random Copolymer Micelles

Ilin Sadeghi, Jacob Kronenberg, and Ayse Asatekin

Anisotropic Growth of Hydroxyapatite in Stretched Double Network Hydrogel

Kazuki Fukao, Takayuki Nonoyama, Ryuji Kiyama, Kazuya Furusawa, Takayuki Kurokawa, Tasuku Nakajima, and Jian Ping Gong

The Molecular Mechanism of Nanodroplet Stability

Evangelia Zdrali, Yixing Chen, Halil I. Okur, David M. Wilkins, and Sylvie Roke

Rapid Ordering in “Wet Brush” Block Copolymer/Homopolymer Ternary Blends

Gregory S. Doerk and Kevin G. Yager

December 2017

The Relationship of Collagen Structural and Compositional Heterogeneity to Tissue Mechanical Properties: A Chemical Perspective

Junjie Chen, Taeyong Ahn, Isabel D. Colón-Bernal, Jinhee Kim, and Mark M. Banaszak Holl

A Charge-Density-Tunable Three/Two-Dimensional Polymer/Graphene Oxide Heterogeneous Nanoporous Membrane for Ion Transport

Xuanbo Zhu, Yahong Zhou, Junran Hao, Bin Bao, Xiujie Bian, Xiangyu Jiang, Jinhui Pang, Haibo Zhang, Zhenhua Jiang, and Lei Jiang

Duplicating Dynamic Strain-Stiffening Behavior and Nanomechanics of Biological Tissues in a Synthetic Self-Healing Flexible Network Hydrogel

Bin Yan, Jun Huang, Linbo Han, Lu Gong, Lin Li, Jacob N. Israelachvili, and Hongbo Zeng

Effects of Grafting Density on Block Polymer Self-Assembly: From Linear to Bottlebrush

Tzu-Pin Lin, Alice B. Chang, Shao-Xiong Luo, Hsiang-Yun Chen, Byeongdu Lee, and Robert H. Grubbs

Where Ion Mobility and Molecular Dynamics Meet To Unravel the (Un)Folding Mechanisms of an Oligorotaxane Molecular Switch

Emeline Hanozin, Benoit Mignolet, Denis Morsa, Damien Sluysmans, Anne-Sophie Duwez, J. Fraser Stoddart, Françoise Remacle, and Edwin De Pauw

October 2017

Imaging of Biological Materials and Cells by X-ray Scattering and Diffraction

Clément Y. J. Hémonnot and Sarah Köster

September 2017

Assessment of Local Heterogeneity in Mechanical Properties of Nanostructured Hydrogel Networks

Zhaokai Meng, Teena Thakur, Chandani Chitrakar, Manish K. Jaiswal, Akhilesh K. Gaharwar, and Vladislav V. Yakovlev

Microinjection for the ex Vivo Modification of Cells with Artificial Organelles

Peter Tiefenboeck, Jong Ah Kim, Ferdinand Trunk, Tamara Eicher, Erica Russo, Alvaro Teijeira, Cornelia Halin, and Jean-Christophe Leroux

August 2017

Distinct Chemical and Physical Properties of Janus Nanosheets

Al C. de Leon, Bradley J. Rodier, Qinmo Luo, Christina M. Hemmingsen, Peiran Wei, Kevin Abbasi, Rigoberto Advincula, and Emily B. Pentzer

Characterizing Single Polymeric and Protein Nanoparticles with Surface Plasmon Resonance Imaging Measurements

Adam M. Maley, George J. Lu, Mikhail G. Shapiro, and Robert M. Corn

April 2017

Direct Cytosolic Delivery of CRISPR/Cas9-Ribonucleoprotein for Efficient Gene Editing

Rubul Mout, Moumita Ray, Gulen Yesilbag Tonga, Yi-Wei Lee, Tristan Tay, Kanae Sasaki, and Vincent M. Rotello

Control of Ice Formation

Ching-Wen Lo, Venkataraman Sahoo, and Ming-Chang Lu

Ion Effect and Metal-Coordinated Cross-Linking for Multiscale Design of Nereis Jaw Inspired Mechanomutable Materials

Chia-Ching Chou, Francisco J. Martin-Martinez, Zhao Qin, Patrick B. Dennis, Maneesh K. Gupta, Rajesh R. Naik, and Markus J. Buehler

February 2017

Immunological Principles Guiding the Rational Design of Particles for Vaccine Delivery

Katelyn T. GauseAdam K. WheatleyJiwei CuiYan YanStephen J. KentFrank Caruso

Artificial Virus Delivers CRISPR-Cas9 System for Genome Editing of Cells in Mice

Ling LiLinjiang SongXiaowei LiuXi YangXia LiTao HeNing WangSuleixin YangChuan YuTao YinYanzhu WenZhiyao HeXiawei WeiWeijun SuQinjie WuShaohua YaoChangyang GongYuquan Wei

Probing Molecular Mechanisms of Self-Assembly in Metal–Organic Frameworks

Debasmita BiswalPeter G. Kusalik

January 2017

Blood–Brain-Barrier-Penetrating Albumin Nanoparticles for Biomimetic Drug Delivery via Albumin-Binding Protein Pathways for Antiglioma Therapy

Tingting LinPengfei ZhaoYifan JiangYisi TangHongyue JinZhenzhen PanHuining HeVictor C. Yangand Yongzhuo Huang

October 2016

Combining Immune Checkpoint Inhibitors and Kinase-Inhibiting Supramolecular Therapeutics for Enhanced Anticancer Efficacy

Ashish Kulkarni, Siva Kumar Natarajan, Vineethkrishna Chandrasekar, Prithvi Raj Pandey, and Shiladitya Sengupta

September 2016

Neuron-Targeted Nanoparticle for siRNA Delivery to Traumatic Brain Injuries

Ester J. Kwon, Matthew Skalak, Riana Lo Bu, and Sangeeta N. Bhatia

Chirality-Discriminated Conductivity of Metal–Amino Acid Biocoordination Polymer Nanowires

Jianzhong Zheng, Yijin Wu, Ke Deng, Meng He, Liangcan He, Jing Cao, Xugang Zhang, Yaling Liu, Shunxing Li, and Zhiyong Tang

June 2016

Mapping Buried Hydrogen-Bonding Networks

John C. Thomas, Dominic P. Goronzy, Konstantin Dragomiretskiy, Dominique Zosso, Jérôme Gilles, Stanley J. Osher, Andrea L. Bertozzi, and Paul S. Weiss

Acoustically Propelled Nanomotors for Intracellular siRNA Delivery

Berta Esteban-Fernández de Ávila, Chava Angell, Fernando Soto, Miguel Angel Lopez-Ramirez, Daniela F. Báez, Sibai Xie, Joseph Wang, and Yi Chen

March 2016

Suppression of Hepatic Inflammation via Systemic siRNA Delivery by Membrane-Disruptive and Endosomolytic Helical Polypeptide Hybrid Nanoparticles

Hua He, Nan Zheng, Ziyuan Song, Kyung Hoon Kim, Catherine Yao, Rujing Zhang, Chenglin Zhang, Yuhui Huang, Fatih M. Uckun, Jianjun Cheng, Yanfeng Zhang, and Lichen Yin

February 2016

Neutrophil-Mediated Delivery of Therapeutic Nanoparticles across Blood Vessel Barrier for Treatment of Inflammation and Infection

Dafeng Chu, Jin Gao, and Zhenjia Wang

Synthesis of Highly Fluorescent Copper Clusters Using Living Polymer Chains as Combined Reducing Agents and Ligands

Markus J. Barthel, Ilaria Angeloni, Alessia Petrelli, Tommaso Avellini, Alice Scarpellini, Giovanni Bertoni, Andrea Armirotti, Iwan Moreels, and Teresa Pellegrino

Soft Discoidal Polymeric Nanoconstructs Resist Macrophage Uptake and Enhance Vascular Targeting in Tumors

Jaehong Key, Anna Lisa Palange, Francesco Gentile, Santosh Aryal, Cinzia Stigliano, Daniele Di Mascolo, Enrica De Rosa, Minjung Cho, Yeonju Lee, Jaykrishna Singh, and Paolo Decuzzi

Self-Healing Underwater Superoleophobic and Antibiofouling Coatings Based on the Assembly of Hierarchical Microgel Spheres

Kunlin Chen, Shuxue Zhou, and Limin Wu

Micelle-Induced Self-Assembling Protein Nanowires: Versatile Supramolecular Scaffolds for Designing the Light-Harvesting System

Hongcheng Sun, Xiyu Zhang, Lu Miao, Linlu Zhao, Quan Luo, Jiayun Xu, and Junqiu Liu

Substrate-Independent, Transparent Oil-Repellent Coatings with Self-Healing and Persistent Easy-Sliding Oil Repellency

Li Yu, George Y. Chen, Haolan Xu, and Xiaokong Liu

Engineered Carbon-Nanomaterial-Based Electrochemical Sensors for Biomolecules

Jitendra N. Tiwari, Varun Vij, K. Christian Kemp, and Kwang S. Kim

December 2015

Dynamic Cross-Linking of Polymeric Binders Based on Host–Guest Interactions for Silicon Anodes in Lithium Ion Batteries

Tae-woo Kwon, You Kyeong Jeong, Erhan Deniz, Siham Y. AlQaradawi, Jang Wook Choi, and Ali Coskun

Penetrating the Blood–Brain Barrier: Promise of Novel Nanoplatforms and Delivery Vehicles

Iqbal Unnisa Ali and Xiaoyuan Chen

Chemical Control over Cellular Uptake of Organic Nanoparticles by Fine Tuning Surface Functional Groups

Yugang Bai, Hang Xing, Peiwen Wu, Xinxin Feng, Kevin Hwang, Jennifer M. Lee, Xin Yi Phang, Yi Lu, and Steven C. Zimmerman

Cuboplexes: Topologically Active siRNA Delivery

Hojun Kim and Cecilia Leal

Toward Anisotropic Hybrid Materials: Directional Crystallization of Amphiphilic Polyoxazoline-Based Triblock Terpolymers

Tobias Rudolph, Moritz von der Lühe, Matthias Hartlieb, Sebastien Norsic, Ulrich S. Schubert, Christophe Boisson, Franck D’Agosto, and Felix H. Schache

October 2015

Cell-Membrane-Mimicking Lipid-Coated Nanoparticles Confer Raman Enhancement to Membrane Proteins and Reveal Membrane-Attached Amyloid-β Conformation

Debanjan Bhowmik, Kaustubh R. Mote, Christina M. MacLaughlin, Nupur Biswas, Bappaditya Chandra, Jaydeep K. Basu, Gilbert C. Walker, Perunthiruthy K. Madhu, and Sudipta Maiti

Transparent Stretchable Self-Powered Patchable Sensor Platform with Ultrasensitive Recognition of Human Activities

Byeong-Ung Hwang, Ju-Hyuck Lee, Tran Quang Trung, Eun Roh, Do-Il Kim, Sang-Woo Kim, and Nae-Eung Lee

August 2015

Crystalline Oligo(ethylene sulfide) Domains Define Highly Stable Supramolecular Block Copolymer Assemblies

Carrie E. Brubaker, Diana Velluto, Davide Demurtas, Edward A. Phelps, and Jeffrey A. Hubbell

June 2015

Nanocomposite Hydrogels: 3D Polymer–Nanoparticle Synergies for On-Demand Drug Delivery

Sonia Merino, Cristina Martín, Kostas Kostarelos, Maurizio Prato, and Ester Vázquez

Identifying the Location of a Single Protein along the DNA Strand Using Solid-State Nanopores

Jae-Seok Yu, Min-Cheol Lim, Duyen Thi Ngoc Huynh, Hyung-Jun Kim, Hyun-Mi Kim, Young-Rok Kim, and Ki-Bum Kim

Nature-Inspired DNA Nanosensor for Real-Time in Situ Detection of mRNA in Living Cells

Chor Yong Tay, Liang Yuan, and David Tai Leong

April 2015

Direct Aqueous Self-Assembly of an Amphiphilic Diblock Copolymer toward Multistimuli-Responsive Fluorescent Anisotropic Micelles

Gang Wu, Si-Chong Chen, Chang-Lei Liu, and Yu-Zhong Wang

Hierarchically Functionalized Magnetic Core/Multishell Particles and Their Postsynthetic Conversion to Polymer Capsules

Sophia Schmitt, Martin Silvestre, Manuel Tsotsalas, Anna-Lena Winkler, Artak Shahnas, Sylvain Grosjean, Fabrice Laye, Hartmut Gliemann, Joerg Lahann, Stefan Bräse, Matthias Franzreb, and Christof Wöll

Design and Synthesis of Bubble-Nanorod-Structured Fe2O3–Carbon Nanofibers as Advanced Anode Material for Li-Ion Batteries

Jung Sang Cho, Young Jun Hong, and Yun Chan Kang

On-Demand Delivery of Single DNA Molecules Using Nanopipets

Aleksandar P. Ivanov, Paolo Actis, Peter Jönsson, David Klenerman, Yuri Korchev, and Joshua B. Edel

Nanoscale Strategies: Treatment for Peripheral Vascular Disease and Critical Limb Ischemia

Chengyi Tu, Subhamoy Das, Aaron B. Baker, Janeta Zoldan, and Laura J Suggs