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Excess bile secretion

Where is bile secreted and what does it contain?

Bile is secreted in the liver and discharge into duodenum. It contains bile salts, bile acid, bile pigment,neutral fat, phospholipid, electrolytes like na ions and water.
Secretion of Bile and the Role of Bile Acids In Digestion 

Bile is a complex fluid containing water, electrolytes and a battery of organic molecules including bile acids, cholesterol, phospholipids and bilirubin that flows through the biliary tract into the small intestine. There are two fundamentally important functions of bile in all species:

Bile contains bile acids, which are critical for digestion and absorption of fats and fat-soluble vitamins in the small intestine.

Many waste products are eliminated from the body by secretion into bile and elimination in feces.
Adult humans produce 400 to 800 ml of bile daily, and other animals proportionately similar amounts. The secretion of bile can be considered to occur in two stages:

As bile flows through the bile ducts it is modified by addition of a watery, bicarbonate-rich secretion from ductal epithelial cells.
In species with a gall bladder (man and most domestic animals except horses and rats), further modification of bile occurs in that organ. The gall bladder stores and concentrates bile during the fasting state. Typically, bile is concentrated five-fold in the gall bladder by absorption of water and small electrolytes - virtually all of the organic molecules are retained.

Secretion into bile is a major route for eliminating cholesterol. Free cholesterol is virtually insoluble in aqueous solutions, but in bile, it is made soluble by bile acids and lipids like lethicin. Gallstones, most of which are composed predominantly of cholesterol, result from processes that allow cholesterol to precipitate from solution in bile.

Role of Bile Acids in Fat Digestion and Absorption

Bile acids are derivatives of cholesterol synthesized in the hepatocyte. Cholesterol, ingested as part of the diet or derived from hepatic synthesis is converted into the bile acids cholic and chenodeoxycholic acids, which are then conjugated to an amino acid (glycine or taurine) to yield the conjugated form that is actively secreted into cannaliculi.


reference and acknowledgements to --boldsky.com
http://www.boldsky.com/health/disorders-cure/2013/causes-of-excess-bile-secretion-033869.html

Overeating
 
There is excess bile secretion when an individual overeats or consumes more food than is deemed necessary by the body. When there is an excess consumption of food, the body stores it away. When this unused nutrient material gets to be too large a quantity for the body to store, the body rectifies this problem by excess bile secretion. This will help relieve the system for a time period of four to six weeks, after which the process is repeated. 

Food quality
 
Extremely rich food causes excess bile secretion. Food that has gone bad due to improper storage or unhygienic methods of preparation also results in excess bile secretion. This can be avoided by steering clear of food from outside. Always make sure that you prepare food in a healthy manner. Stay away from food that is left uncovered or not refrigeriated. Make sure the food you eat is not too rich. 

Lack of Exercise 

When an individual is temped to overeat, but does not exercise or burn a corresponding amount of calories by doing vigorous activities, there is an overload on the liver. This results in excess bile secretion or a bilious attack. The liver stops its function until the excess food is expelled with the help of bile. 

Peptic Ulcer 

Sometimes excess bile secretions occur as a result of peptic ulcers. These ulcers block the pyloric valve, which prevents the stomach from opening to empty the food as quickly as it does normally. This leads to food becoming stagnant in the stomach. This increases gastric pressure that in turn increases the secretion of bile and causes excess bile secretion into the oesophagus. Excess secretion of bile results in indigestion and constipation. It also results in nausea, headache, loss of mental efficiency and depression. Excess bile secretion should immediately be remedied as according to the method of manifestation. Proper diet and regular exercise is also necessary for avoiding excess bile secretion.


 
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