2019 spring

Syllabus (pdf)

Lecture notes

• • • Overview (1)

    • Feinberg ( 2, 3, 4, 5, 6-7, 8-9)

    • Ha (10, 11, 12, 13, 14, 15, 16 (Bowman), 17)

2018 spring

Student presentations

• • 1. Dynamic Organization of Chromatin Domains Revealed by Super-Resolution Live-Cell Imaging (pdf)

    2. Nucleosome breathing and remodeling constrain CRISPR-Cas9 function (pptx)

    3. DNA topology in chromatin is defined by nucleosome spacing (pptx)

    4. A Phase Separation Model for Transcriptional Control (pptx)

    5. A pathway for mitotic chromosome formation (pdf)

    6. 3D Chromatin Structure Prediction (pptx)

    7. Tracing dynamic changes of DNA methylation at single-cell resolution (pdf)

Student News and Views style articles (pdf)

2017 spring

Student presentations

• • 1. Dynamics of Epigenetic Regulation at the Single-Cell Level (pptx)

    2. Spatial Organization of Chromatin Domains and Compartments in single chromosomes (pptx)

    3. Insulator dysfunction and oncogene activation in IDH mutant gliomas (pptx)

    4. Epigenetic inheritance uncoupled from sequence-specific recruitment (pdf)

    5. Single cell chromatin accessibility reveals principles of regulatory variation (pdf)

    6. Nucleosomal Elements that Control the Topography of the Barrier to Transcription (pptx)

    7. Intragenic DNA methylation prevents spurious transcription initiation (pdf)

    8. Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes (pdf)

Student News and Views style articles (pdf)