Somatic variant calling workflow for matched tumor-normal samples

Please note that this Strelka release has been superseded by Strelka2. Source code and documentation for Strelka2 can be found here:

Documentation from the original Strelka release remains at this site for reference, but development and support are inactive.

Strelka is an analysis package designed to detect somatic SNVs and small indels from the aligned sequencing reads of matched tumor-normal samples.

The links on this page provide basic information on setting up, running and interpreting the results from this tool.

The method itself is described in the following publication:

Please send any questions, comments or discussion related to the software or methods to the strelka-discuss mailing list.