Somatic variant calling workflow for matched tumor-normal samples

Strelka is an analysis package designed to detect somatic SNVs and small indels from the aligned sequencing reads of matched tumor-normal samples.

The links on this page provide basic information on setting up, running and interpreting the results from this tool.

The method itself is described in the following publication:

Please send any questions, comments or discussion related to the software or methods to the strelka-discuss mailing list.