Department of Biochemistry & Biophysics at The University of North Carolina, Chapel Hill

Welcome to the Campbell Lab

We are a research group in the Department of Biochemistry & Biophysics at University of North Carolina, Chapel Hill. We apply structural, biophysical and biochemical approaches to investigate Ras and Rho GTPases as well as the cell adhesion proteins, focal adhesion kinase, vinculin and paxillin. Aberrant regulation of these molecules is linked to a variety of disease states, including cancer, cardiovascular and neurological disorders. Our studies are conducted in collaboration with cell biology groups to better correlate molecule information with cellular function.

Recent News

  • New paradigms in Ras research Ras is a family of genes encoding small GTPases involved in cellular signal transduction. If their signals are dysregulated, Ras proteins can cause cancer. Dr. Sharon Campbell explains her lab’s research into a novel mechanism for regulation of Ras proteins by reactive free radical species.
    Posted Aug 5, 2010, 8:44 AM by sharon campbell
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