Structures


Gene

Structures

PDB Files

ABL1

ABL1

SH2

SH3 + SH2

SH2 + Monobody

1OPJ, 1OPK, 1OPL

1AB2

2ABL, 2FO0

3T04, 3K2M, 3UYO

ABL2

SH2

2ECD4EIH

APS

SH2 Dimer

SH2 + INSR

1RPY

1RQQ

BLK

SH2

1BLJ, 1BLK

BLNK

SH2

2EO6

BKS

SH2

2EL8

BMX

SH2

2EKX

BRK

SH2

1RJA

BTK

SH2

2GE9

CBL

CBL + UBCH

TKB(SH2) + peptide

TKB(SH2)

TKB(SH2) + peptide+E2

1FBV

1YVH, 3BUM, 3BUN, 3BUO, 3BUW, 3BUX, 2Y1N

1B47, 2CBL

4A4B

 CBLC TKB (SH2) 
 TKB (SH2) + peptide                
 3VRN
 3VRO, 3VRP

CHN1

CHN1

1XA6, 3CXL

CRK

SH2

SH2 + ABL SH3 + peptide

CRK

2EYV

1JU5

2DVJ

CRKL

SH2

CRKL    

2EO3

2LQN, 2LQW

CSK

SH2

CSK + peptide

CSK

1JWO

2RSY

1K9A

FES

SH2

FES

FES + peptide

1WQU

3BKB

3CBL, 3CD3

FYN

SH2

SH2 + peptide

SH2 + SH3

FYN + SAP + SLAM peptide

2DLY

1AOT, 1AOU

1G83, 3UF4

1M27

GADS

SH2 + peptide

1R1P, 1R1Q, 1R1S

GRB2

SH2

SH2 + peptide

SH2 + inhibitor

GRB2

1FHS, 1GHU, 1JYU, 3C7I

1BM2, 1BMB, 1FYR, 1JYQ, 1JYR, 1TZE, 1QG1, 1ZFP, 2H5K, 3OV1, 3S8N, 3S8O

1CJ1, 1X0N, 2AOA, 2AOB, 2HUW

1GRI

GRB7

SH2

SH2 + peptide

2QMS

1MW4, 3PQZ

GRB10

SH2

1NRV

GRB14

SH2

2AUG

HCK

SH2

HCK

HCK + inhibitor

3HCK

1AD5, 2HCK

1QCF

HSH2D

SH2

2CS0

ITK

SH2

SH2 + peptide

1LUI, 1LUK, 1LUM, 1LUN

2EU0, 2ETZ

LCK

SH2 + inhibitor

SH2

SH3-SH2

SH2 + peptide

SH3 + SH2 + peptide

LCK

1BHF, 1IJR

1BHH

4D8K

1LCJ, 1LKK, 1LKL

1LCK, 1X27

1CWD, 1CWE,

 

 MATK

 

SH2


 

 3US4

NCK1

SH2

SH2 + peptide

2CI8

2CI9

NCK2

SH2 + peptide

NCK2

1Z3K, 2CIA

4E6R

PLCG1

N&C_SH2


C_SH2 + peptide

4EY0, 4FBN


2FCI, 2PLE, 2PLD

PLCG2

N_SH2

C_SH2

2DX0

2EOB

PIK3R1

N_SH2

N_SH2 + peptide

C_SH2

C_SH2 + peptide

2PNA, 2PNB, 1OO3, 1FU6, 2IUG, 2V1Y

1FU5, 1OO4, 2IUH, 2IUI

1BFI, 1BFJ

1H9O, 1PIC, 1QAD

PTPN6

PTPN6

C_SH2

C_SH2 + peptide

2B3O, 3PS5

1X6C

2YU7, 2RMX

PTPN11

PTPN11

N_SH2

N_SH2 + peptide

2SHP, 3MOW

1AYA, 1AYB, 1AYC, 1AYD

2YU7, 3TKZ, 3TL0

RASA1

C_SH2

2GSB

SH2B

SH2 + peptide

2HDX, 2HDV

SH2D1A

SAP

SAP + peptide

SAP + FYN + SLAM peptide

1D1Z

1D4T, 1D4W, 1KA6, 1KA7

1M27

SH2D1B

SH2 + peptide

1I3Z

SH3BP2

SH2

2CR4

SHC1

SH2

SH2 + peptide

1MIL

1TCE

SHIP2

SH2

2YSX

 SLAP2 SH3-SH2    4M4Z

SOCS2

SH2 + peptide

SH2 + ElonginBC

2C9W

4JGH

SOCS3

SH2 + peptide

2BBU, 2HMH

SOCS4

SH2

2IZV

SOCS6

SH2 + peptide

2VIF

 

 SPT6

 

SH2_N&C

SH2_N

 

 2L3T

3GXX, 3GXW

SRC

SH2

SH2 + inhibitor

 

 

SH2 + peptide

 

SRC

SRC SH2 T215W (Grb2) + peptide

1BKL, 1BKM

1O41, 1O42, 1O43, 1O44, 1O45, 1O46, 1O47, 1O48, 1O49, 1O4A, 1O4B, 1O4C, 1O4D, 1O4E, 1O4G, 1O4H, 1O4I, 1O4J, 1O4L, 1O4M, 1O4N, 1O4O, 1O4P, 1O4Q, 104R, 1FBZ, 1IS0, 1SKJ

1A07, 1A08, 1A09, 1A1A, 1A1B, 1A1C, 1A1E, 1HCS, 1HCT, 1KC2, 1NZL, 1NZV, 1P13, 1SHA, 1SHB, 1SHD, 1SPR

1FMK, 1KSW, 1SPS, 2SRC, 2PTK

1F1W, 1F2F

STAT1

STAT1 + DNA

STAT1

STAT1 + peptide

1BF5

1UUR, 1UUS

1YVL

STAT3

STAT3 + DNA

1BG1

STAT5a

STAT5a

1Y1U

SYK

N&C_SH2 + peptide

C_SH2 + peptide

1A81

1CSY, 1CSZ

 

 TNS1

 

SH2 + peptide

 

 2L6K

TXK

SH2

2DM0

 TYK2  FERM + SH2      4PO6

ZAP70

N&C_SH2

N&C_SH2 + peptide

ZAP70

1M61

2OQ1

2OZO, 4K2R

VAV1

SH2

SH2 + peptide

2CRH

2LCT

VAV2

SH2

2DLZ, 2LNX


Ċ
Bernard Liu,
May 21, 2010, 5:34 PM
Comments