Seurat
A matched tumor/normal analysis program for DNA/RNA sequencing data
Seurat detects events unique in cancer DNA when compared to the normal sequenced genome of the same individual. It currently supports detection of small somatic mutations (SNVs/indels), LOH events, structural variation and allelic imbalance.
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Seurat is free to use for academic purposes, and Seurat's manuscript is under review. Author and citation information can be found here.