Research Gate / LinkedIn / Google Scholar

Email: saptaparnighosh@gmail.com

Curriculum vitae


Welcome!!

I am a full-time graduate student in the MS in Clinical Research program in Boston University School of Medicine. I am also working part-time as a Research Assistant at the Framingham Heart Study. I am interested in clinical trials particularly in the field of oncology. My long time goal is to work as a Clinical Research Associate in a pharmaceutical company or CRO.

My current research area involves understanding the effects of concurrent HCV infection in cancer patients getting chemotherapy as a part of their treatment.

I have a Ph.D. in Biochemistry from the University of Calcutta in April 2014. I completed my doctoral work at Saha Institute of Nuclear Physics, Kolkata, India under Prof. Dipak Dasgupta in the Biophysics and Structural Genomics Division. I worked as a Research Associate in the same laboratory for another year.

I am a physical chemist by training and the primary focus of my doctoral work was on the interaction between G-quadruplex DNA and small molecules with anticancer potential to identify plausible alternative ways of targeting cancer cells. My Ph.D. dissertation showed the thermodynamic preference of these small molecules in binding to quadruplex structures over duplex DNA structures. I extended this work further during my postdoctoral tenure where I investigated the role of kinetics, if any, in preferentially binding to the quadruplex structures over duplex structures. I also studied the effect of a small molecule on various epigenetic marks, both in vivo and in vitro.