Benjamin Roche

IRD Researcher

International Center for Mathematical and Computational Modeling of Complex Systems (UMI IRD/UPMC UMMISCO)

32, Avenue Henri Varagnat

93143 Bondy Cedex

France


e-mail : roche.ben@gmail.com

Phone: +33.6.29.58.54.60

Publications: 

(39) Garchitorena A., Guégan J.F., Léger L., Eyangoh S., Marsollier L., Roche B. (in press) Mycobacterium ulcerans dynamics in aquatic ecosystems are driven by a complex interplay of abiotic and biotic factors. eLife.

(38) Ezenwa V., Prieur-Richard A.H., Roche B, Bailly X., García-Peña G., Hosseini P., Keesing F., Rizzoli A.,  Suzán G., Vignuzzi M., Vittecoq M., Mills J., Guégan J.F. (in press) Interdisciplinarity and infectious diseases: an Ebola case study. PLoS Pathogens.


(37) Cazelles B., Tian H., Roche B. (2015) Ecological and
evolutionary approaches to better understand avian influenza epidemics. Med Sci
4(31) :372 - 373

(36) Elguero E., Délicat-Loembet L., Rougeron V., Arnathau C., Roche B., Becquart P., Gonzalez J.P., Nkoghe D., Sica L., Leroy E.M., Durand P., Ayala F.J, Ollomo B., Renaud F., Prugnolle F. (in press) Malaria continues to select for Sickle Cell Trait in Central Africa. PNAS

(35) Delicat-Loembet L., Rougeron V., Ollomo B., Anathau C., Roche B.; Elguero E., Moukodoum N.D., Okougha A.P., Mve Ondo B., Boundenga L., Houze S., Galan M., Nkoghe D.; Leroy E.M., Durand P., Paupy C., Renaud F., Prugnolle F. (in press) No evidence for ape Plasmodium infections in humans in Gabon. PLoS One

(34) Roche B., Elguero E., Morand S., Guégan, J.F., Gaidet, N (in press) Disentangling effects of instrinsic competence and ecological factors for epidemics patterns: The case of West Nile Fever in the US. Infection, Genetics and Evolution

(33) Arnal A., Ujvari B.,Crespi B., Gatenby R., Tissot T.,Vittecoq M., Ewald P., Casali A., Ducasse H., Jacqueline C., Misse D., Renaud F., Roche B., Thomas F. (in press) Evolutionary perspective of cancer: myth, metaphors and reality. Evolutionary Applications

(32) Al-Shorbaji F., Gozlan R., Roche B., Britton R., Andreou D. (in press) The alternate role of direct and environmental transmission in fungal infectious disease in wildlife: threats for biodiversity conservation. Scientific Reports.

(31) Roche B., Léger L., L’Ambert G., Lacour G., Foussadier R., Besnard G., Barré-Cardi H., Simard F., Fontenille D. (in press) The spread of Aedes albopictus in Metropolitan France: contribution of environmental drivers and human activities and predictions for a near future. PLoS One. 

(30) Roche B., Ujvari B., Thomas F. (in press) Bad luck and cancer: Does evolution spin the wheel of fortune? Bioessays

(29) Vittecoq M., Roche B., Cohen J.M., Renaud F., Thomas F., Gauthier-Clerc M. (in press) Does the weather play a role in pandemic influenza spread? A study of H1N1pdm09 infections in France in 2009-2010. Epidemiology and Infection.

(28) Suzán G., García-Peña G.E., Castro-Arellano I., Rico O., Rubio A.V., Tolsá M.J., Roche B., Hosseini P.R., Rizzoli A., Murray K.A., Zambrana-Torrelio C., Vittecoq M., Baiily X., Ezenwa V., Aguirre A.A., Daszak P., Prieur-Richard A.H., Mills J.N., Guégan J.F. (in press) Metacommunity and phylogenetic structure determine wildlife and zoonotic infectious disease patterns in time and space. Ecology and Evolution.

(27) Ducasse H, Arnal A., Vittecoq M., Daoust S.P., Ujvari B., Jacqueline C., Ewald P., Gatenby R.A., King K.C., BonhommeF., Brodeur J., Renaud F., Solary E., Roche B., Thomas F. (in press) Cancer: an emergent property of disturbed resource-rich  environments? Ecology meets personalized medicine. Evolutionary Applications.

(26) Vittecoq M., Ducasse H., Arnal A., Møller A.P., Ujvari B., Jacqueline C., Missé D., Bernex F., Pirot N., Lemberger K., Abadie J., Labrut S., Bonhomme F., Renaud F., Roche B., Thomas F. (in press) Animal behavior and Cancer. Animal Behaviour

(25) Roche B., Broutin H., Choisy M., Godreuil S., Constantin de Magny G., Chevaleyre Y., Zucker J.D., Breban R., Cazelles B. Simard F. (2014) The niche reduction approach: an opportunity for optimal control of infectious diseases in low-income countries? BMC Public Health. 14:753.

(24) Roche B., Drake J. M., Bedford T., Stallknecht D. and Rohani P. (2014) Environmental transmission explains the difference of influenza phylodynamics between birds and humans. PLoS Biology. 12(8):e1001931

(23) Moussaoui A., Auger P., Roche B. (2014) Effect of Hawk-Dove Game on the dynamics of two competing species. Acta Biotheoretica. 62(3):385-404.

(22) Constantin de Magny G., Hasan N.A., Roche B. (2014) How community ecology can improve our understanding of cholera dynamics. Frontiers in Microbiology. 5:137.

(21) Garchitorena A., Roche B., Kamgang R., Ossomba J., Babonneau J., Landier J., Fontanet A., Flahault A., Eyangoh S., Guégan J.F., Marsollier L. (2014) Mycobacterium ulcerans Ecological Dynamics and Its Association with Freshwater Ecosystems and Aquatic Communities: Results from a 12-Month Environmental Survey in Cameroon. PLoS Neglected Tropical Diseases. 8(5):e2879.

(20) Vittecoq M., Roche B., Daoust S.P., Ducasse H., Missé D., Abadie J., Labrut S., Renaud F., Gauthier-Clerc M., Thomas F. (2013) Cancer: a missing link in ecosystem functioning ? Trends in Ecology and Evolution28(11):628-635.

(19) Roche B., Benbow M. E., Merritt R., Kimbirauskas R., McIntosh M., Small P. L. C., Williamson H. and Guégan J.F. (2014) Identifying the Achilles’ heel of multi-host pathogens: The concept of keystone “host” species illustrated by Mycobacterium ulcerans transmission. Environmental Research Letters.8(4): 045009.


(18) Thomas F., Fisher D., Fort P., Marie J.-P., Daoust S., Roche B., Grunau C., Cosseau C., Mitta G., Baghdiguian S., Rousset F., Lassus P., Assenat E., Grégoire D., Missé D., Lorz A., Billy F., Vainchenker W., Delhommeau F., Koscielny S., Itzykson R., Tang R., Fava F., Ballesta A., Lepoutre T., Krasinska L., Dulic V., Raynaud P., Blache P., Quittau-Prevostel C., Vignal E., Trauchessec H., Perthame B., Clairambault J., Volpert V., Solary E., Hibner U. and Hochberg M. E. (2013) Applying ecological and evolutionary theory to cancer: a long and winding road. Evolutionary Applications. 6(1):1-10

(17) Roche B., Sprouffske K., Hbid H., Missé D. and Thomas F. (2013) Peto's paradox revisited: theoretical evolutionary dynamics of cancer in wild populations. Evolutionary Applications. 6(1): 109-116.

(16) Constantin de Magny G., Thiaw W., Kumar V., Manga N.M., Diop B.M., Gueye L., Kamara M., Roche B., Murtugudde R., Colwell R.R. (2012) Cholera outbreak in senegal in 2005: was climate a factor? PloS one. 7 (8), e44577

(15)
Vittecoq M., Lafferty K. D. , Elguero E., Brodeur J., Gauthier-Clerc M., Miss\'e D., Roche B. and Thomas F. (2012) Cat ownership is neither a strong predictor of Toxoplamsa gondii infection nor a risk factor for brain cancer. Biology Letters. rsbl20120625

(14) Roche B., Hochberg M.E., Caulin A.F., Maley C.C., Gatenby R.A., Missé D. and Thomas F. (2012) Natural resistance to cancers: a Darwinian hypothesis to explain Peto's paradox. BMC Cancer. 12:387.


(13) Roche B., Dobson A.P., Rohani P. and Guégan J.F. (2013)  Community organization may drive disease patterns for vector-borne pathogens. The American Naturalist. 181(1): 1-11.


(12) Thomas F., Elguero E., Brodeur J., Roche B., Missé D. and Raymond M (2012) Malignancies and high birth weight in human: which cancers could result from antagonistic pleiotropy? Journal of Evolutionary Medicine. 1: 5

(11) Roche B., Dobson A.P., Guégan J.F. and Rohani P. (2012) Community ecology and epidemiology of infectious diseases: a framework to study pathogen transmission through host communities. Philosophical Transactions of the Royal Society: Biological Sciences. 367:1604.

(10) Vittecoq M., Elguero E., Lafferty K.D., Roche B., Brodeur J., Gauthier-Clerc M., Missé D., Thomas F. (2012) Brain cancer mortality rates increase with Toxoplasma gondii seroprevalence in France. Infection, Genetics and Evolution. 12:496–498 [Link]

(9) Roche B., Drake J.M. and Rohani P. (2011) The curse of the pharaoh revisited: Evolutionary bi-stability in environmentally transmitted pathogens. Ecology Letters. 14(6):569-575 [Link]

(8) Roche B., Drake J.M. and Rohani P. (2011An agent-based model to study the epidemiological and evolutionary dynamics of influenza viruses. BMC Bioinformatics. 12:87 [Link]

(7) Roche B. and Guégan J.F. (2011

Ecosystem dynamics, biological diversity and emerging infectious diseases

Comptes Rendus Biologie. 334:385-392 [Link]

(6) Ottaviani D., de la Rocque S., Khomenko S., Gilbert M., Newman S., Roche B., Schwabenbauer K., Pinto J., Slingenbergh J. (2010) HPAI H5N1 virus in Europe survives during the winter at the cold limit of the migratory waterfowl distribution. EcoHealth. 7(2):226-236 [Link]

(5) Roche B. and Rohani P. (2009) Environmental transmission scrambles coexistence patterns for Avian Influenza Viruses. Epidemics. 2(2):92-98 [Link]

(4) Roche B., Lebarbenchon C., Gauthier-Clerc M., Chang C.M., Thomas F., Renaud F., van der Werf S. and Guégan J.F. (2009). Water-borne transmission drives avian influenza dynamics in wild birds: the case of the 2005-2006 epidemics in the Camargue area  Infection, Genetics and Evolution. 9:800-805 [Link]

(3) Roche B., Guégan J.F., Bousquet F. (2008) Multi-agent systems in epidemiology: A first step for computational biology in the study of vector-borne disease transmission (2008). BMC BioInformatics. 9:435 [Link]

(2) Lefèvre T., Roche B., Poulin R., Hurd H., Renaud F. and Thomas F. (2008) Exploiting host compensatory responses: The must of manipulation? Trends in Parasitology. 24(10): 435-439 [Link]

(1) Lebarbenchon C., Van Der Werf S., Thomas F., Aubin J.T., Azebi S., Cuvelier F., Jeannin P., Roca V., Chang C.-M., Kayser Y., Roche B., Guégan J.F., Renaud F., Gauthier-Clerc M.  (2007)  Absence of detection of highly pathogenic H5N1 in migratory waterfowl in southern France in 2005-2006. Infection, Genetics and Evolution, 7(5): 604-608, September 2007. [Link]


Edited Book:

Vittecoq M., Roche B., Prugnolle F., Renaud F., Gauthier-Clerc M., Thomas F. (2015) Evolution, Medecine and Health: the case of infectious diseases. De Boeck University, Louvain, Belgique (French textbook).

Book chapters:

Roche B. (2015) How evolutionary biology has changed public health strategies? in Evolution, Medecine and Health: the case of infectious diseases (Vittecoq M., Roche B., Prugnolle F., Renaud F., Gauthier-Clerc M., Thomas F. eds.). De Boeck University, Louvain, Belgique (French textbook).

Roche B. (2013) Biodiversity and infectious diseases: the example of dilution effect in Biodiversity and Health (Pipien G. and Morand S. eds.). Buchet-Chastel, Arles, France (French textbook).

Roche B. and Guégan J.F. (2010) Biodiversity and infectious diseases in Ecology and Evolution (Gauthier-Clerc M. and Thomas F. eds.). De Boeck Université, Louvain, Belgique. (French textbook).

Franc A, Peyrard N., Roche B. (2008) Infectious diseases in networks in Introduction to quantitative epidemiology of infectious diseases, (Guégan J.F. and Choisy M. eds.). De Boeck Université, Louvain, Belgique.  Pp 81-116 (French textbook).

Roche B., Guégan J.F. (2008) Community epidemiology: An history of mediation between ecosystems and microbes. in Introduction to quantitative epidemiology of infectious diseases (Guégan J.F. and Choisy M. eds.). De Boeck Université, Louvain, Belgique. Pp 117-164. (French textbook).

  

Conferences:

Roche B. Adaptive evolution and environmental durability jointly structure phylodynamic patterns in Avian Influenza Viruses. RAPIDD Workshop, March 19-20th 2015, Cambridge, UK. Invited

Roche B. Buruli ulcer: The interactions between ecosystem, human and economic components do matter! World Health Organization Meeting on Buruli Ulcer, March 23th 2015, WHO Headquarters, Geneva.

García-Peña G.E., Garchitorena A.,Carolan K., Canard E., Prieur-Richard A.H., Suzán G., Mills J., Roche B., Guégan J.F. Disassembly rules influence presence of the environmentally acquired pathogen, Mycobacterium ulcerans. BES and SFÉ Joint Annual Meeting, December 9th 2014, Lille, France.

Roche B. Should we eradicate all parasites? Biodiversity and Health meeting, October 27th 2014, Ecole Veterinaire de Marcy l’Etoile. Invited.

Roche B. Dilution effect: current state of art. Biodiversity and Health meeting, October 27th 2014, Ecole Veterinaire de Marcy l’Etoile. Invited.

Roche B. Reciprocal links between biodiversity and health. Séminaires du Val de Grâce, March 27th 2014, Paris, France. Invited.

Roche B. Adaptive evolution and environmental durability jointly structure phylodynamics patterns in avian influenza viruses. Departmental Seminar of “Evolution and Biological diversity” lab, December 19th 2013, Toulouse, France. Invited

Roche B., Bourfia Y., Hbid H., Thomas F. Dynamics of immune system and accumulation of cancerous cells. Mathematics in cancer Dynamics, January 23rd-25th 2014, Marrakech, Morroco. Invited.

Roche B., Léger L., Elguero E., Fontenille D. Dispersion d’Aedes albopictus en France métropolitaine. Retex Dengue-Chikungunya, Ministère de la Santé, December 6th 2013, Paris, France. Invited.

Roche B., Bourfia Y., Hbid H., Thomas F. Dynamics of immune system and accumulation of cancerous cells. Ecological and Evolutionary aspects in Cancer, Conférence Jacques Monod, May 2d-5th 2013, Rocoff, France.

Roche B., Dobson A.P., Rohani P., Guégan J.F. Linking community and disease ecology: The impact of species diversity on pathogen transmission. Planet Under Pressure, March 25th-29th 2011, London, UK. Invited.

Roche B. Host and pathogen biodiversity: Which impact for public health? Biodiversity and Emerging Infectious Diseases, 22-23 November 2010, Reunion island, France. Invited.

Roche B. Influence of host biodiversity on predictability of spatio-temporal dynamics of vector-borne diseases. Conference on Mathematical and Computational Modeling of Complex Systems, 11-13 October 2010, Paris, France. Invited.

Roche B., Drake J.M. Rohani P. Phylodynamics of influenza viruses: what is the role of environmental transmission? Ecology and Evolution of Infectious Diseases, 3-5 June 2010, Cornell University, Ithaca, NY, USA. (Poster).

Roche B., Benbow M.E. and Guégan J.F. Modeling transmission of Mycobacterium ulcerans through local food webs. Annual meeting on Buruli Ulcer Initiative, 31 March - 2 April 2008, Geneva, International Conference Center, Switzerland. (Oral communication).

Roche B.
and Guégan J.F. Avian influenza is water-borne transmitted. Workshop ``Shared traits, extended phenotypes or GxGxE interactions'', 5 December 2007, Paris, France (Oral communication).

Roche B.
and Guégan J.F. Ecosystem dynamics may drive disease dynamics in wildlife. Seminar at NSF/NIH Fogarty Center, 27 August 2007, Washington D.C., USA (Oral communication). Invited

Roche B.
and Guégan J.F. Community structure and composition: Implications for wildlife disease dynamics. ESA Annual meeting, 5-10 August 2007, San Jose, USA (Oral communication).

Roche B. and Guégan J.-F. (2006) Spatial behavior of multi-host vector-borne diseases. Ecology and Evolution of Infectious Diseases, Penn State, USA ([posterEEID.pdf])

Roche B. and Guégan J.-F. (2006) Impact of community composition and structure on disease dynamics in wildlife. EcoHealth, Madison, USA ([presentationMadison.pdf])