Publications and Presentations

Publications:     ResearcherID
2006 – present  (During Postdoctoral Training):
1.                  Tinoco, I., Jr., Chen, G., and Qu, X. (2010) RNA reactions one molecule at a time, in The RNA World,4th ed. (Gesteland, R.F., Cech, T.R., and Atkins, J.F., Eds.), Cold Spring Harbor Laboratory Press.

2.                  Chen, G., Chang, K.-Y., Chou, M.-Y., Bustamante, C., and Tinoco, I., Jr., (2009)Triplex structures in an RNA pseudoknot enhance mechanical stability and increase efficiency of –1 ribosomal frameshifting. Proc. Natl. Acad. Sci. USA 106, 12706-12711. (Cover Highlight and In This Issue Highlight)

3.                 
Chen, G., Wen, J.-D., and Tinoco, I., Jr., (2007) Single-molecule mechanical unfolding and folding of a pseudoknot in human telomerase RNA. RNA 13, 2175-2188.   PDF

2001 – 2005  (During Graduate Study):
4.                 
Chen, G., Kennedy, S. D., and Turner, D. H., (2009) A CA+ pair adjacent to a sheared GA or AA pair stabilizes size-symmetric RNA internal loops. Biochemistry   48, 5738-5752.

5.                 
Chen, G., Kierzek, R., Yildirim, I., Krugh, T. R., Turner, D. H., and Kennedy, S. D., (2007) Stacking effects on local structure in RNA: Changes in the structure of tandem GA pairs when flanking GC pairs are replaced by isoG-isoC pairs. J. Phys. Chem. B 111, 6718-6727.   PDF   Supporting Information  2O81  2O83

6.                  Shankar, N., Kennedy, S. D., Chen, G., Krugh, T. R., and Turner, D. H. (2006) The NMR structure of an internal loop from 23S ribosomal RNA differs from its structure in crystals of 50S ribosomal subunits. Biochemistry 45, 11776-11789.   PDF   Supporting Information  2H49      (Listed as one of fifteen "Hot Articles" in Nov. 2006 in Biochemistry)

7.                 
Chen, G., Kennedy, S. D., Qiao, J., Krugh, T. R., and Turner, D. H. (2006) An alternating sheared AA pair and elements of stability for a single sheared purine-purine pair flanked by sheared GA pairs in RNA. Biochemistry 45, 6889-6903.   PDF   Supporting Information  2DD1  2DD2  2DD3

8.                 
Chen, G., and Turner, D. H. (2006) Consecutive GA pairs stabilize medium-size RNA internal loops. Biochemistry 45, 4025-4043.   PDF   Supporting Information    
(Listed as one of four "Hot Articles" in Mar. 2006 in Biochemistry)

9.                  Chen, G., Znosko, B. M., Kennedy, S. D., Krugh, T. R., and Turner, D. H. (2005) Solution structure of an RNA internal loop with three consecutive sheared GA pairs. Biochemistry 44, 2845-2856.   PDF   Supporting Information  1XV0       
(Listed as one of five "Hot Articles" in Feb. 2005 in Biochemistry)

10.              Chen, G., Znosko, B. M., Jiao, X., and Turner, D. H. (2004) Factors affecting thermodynamic stabilities of RNA 3 × 3 internal loops. Biochemistry 43, 12865-12876.   PDF   Supporting Information

1996 – 2001  (During Undergraduate Study):
11.             
Cui, Y., Chen, G., Ren, J., Shao, M., Xie, Y., and Qian, Y. (2003) Solvothermal syntheses of b-Ag2Se crystals with novel morphologies. J. Solid State Chem. 172, 17-21.   PDF

12.             
Cui, Y., Chen, J., Chen, G., Ren, J., Yu, W., and Qian, Y. (2001) Bis(2,2-bipyridine-N,N')tetra-m-chloro-tetracopper(I). Acta Crystallogr. Sect. C-Cryst. Struct. Commun. 57, 349-351.   PDF

13.             
Shao, M., Mo, M., Cui, Y., Chen, G., and Qian, Y. (2001) The effect of agitation states on hydrothermal synthesis of Bi2S3 nanorods. J. Cryst. Growth 233, 799-802.   PDF

14.             
Cui, Y., Ren, J., Chen, G., Qian, Y., and Xie, Y. (2001) A simple route to synthesize MInS2 (M = Cu, Ag) nanorods from single-molecule precursors. Chem. Lett. 236-237.   PDF

15.             
Cui, Y., Ren, J., Chen, G., Yu, W., and Qian, Y. (2000) Poly[lead(II)-m-4,4-bipyridine-N,N'-di-m-bromo]. Acta Crystallogr. Sect. C-Cryst. Struct. Commun. 56, E552-E553.   PDF

16.             
Cui, Y., Chen, G., Ren, J., Qian, Y., and Huang, J. (2000) Syntheses, structures and magnetic behaviors of di- and trinuclear pivalate complexes containing both cobalt(II) and lanthanide(III) ions. Inorg. Chem. 39, 4165-4168.   PDF

17.             
Cui, Y., Zhang, X., Zheng, F., Ren, J., Chen, G., Qian, Y., and Huang, J. (2000) Two mixed-metal carboxylate-base adducts. Acta Crystallogr. Sect. C-Cryst. Struct. Commun. 56, 1198-1200.   PDF


Presentations:

1.   Chen, G. (September 2010, Talk) Triplex structures in an RNA pseudoknot enhance mechanical stability and increase efficiency of –1 ribosomal frameshifting.  Department of Chemistry, National University of Singapore, Singapore

2.   Chen, G., Chou, M.-Y., Chang, K.-Y., and Tinoco, I., Jr. (June 2009, Poster) Triplex structures in an RNA pseudoknot enhance mechanical stability and increase efficiency of –1 ribosomal frameshifting.  Bay Area All RNA Meeting, University of California, San Francisco

3.   Chen, G., Chou, M.-Y., Chang, K.-Y., and Tinoco, I., Jr., (May 2009, Poster) Triplex structures in an RNA pseudoknot enhance mechanical stability and increase efficiency of –1 ribosomal frameshifting.Annual Meeting of the RNA Society, Madison, Wisconsin. (Selected as NSMB sponsored “The Best Poster in Biophysics and Structural Biology”)

4.   Chen, G., Chou, M.-Y., Chang, K.-Y., and Tinoco, I., Jr., (April 2009, Talk) Triplex structures in an RNA pseudoknot enhance mechanical stability and increase efficiency of –1 ribosomal frameshifting. RNA Club, Center for Molecular Biology of RNA, University of California, Santa Cruz

5.   Chen, G. (January 2009, Job Talk) Base triples in RNA pseudoknots modulate mechanical stability and –1 ribosomal frameshifting efficiency. Department of Pharmaceutical Sciences, University of Nebraska Medical Center

6.   Chen, G., Wen, J.-D., and Tinoco, I., Jr. (February 2008, Poster) Single-molecule mechanical unfolding and folding of a pseudoknot in human telomerase RNA.  Biophysical Society Meeting, Long Beach, CA 

7.   Chen, G., Wen, J.-D., and Tinoco, I., Jr. (December 2007, Poster) Single-molecule mechanical unfolding and folding of a pseudoknot in human telomerase RNA.  Bay Area All RNA Meeting, University of California, San Francisco

8.   Chen, G., Wen, J.-D., and Tinoco, I., Jr. (August 2006, Invited Talk)   Mechanical manipulation of a pseudoknot from human telomerase RNA.  Turner Symposium, University of Rochester

9.   Chen, G., Kennedy, S.D., Znosko, B.M., Jiao, X., Krugh, T.R., and Turner, D.H. (November 2005, Talk) Expanded Sequence Dependence Improves Prediction of RNA Internal Loop Stability and NMR Reveals Molecular Recognition Interactions Accounting for Stability, Structure, and Dynamics.  RNA Structure and Function Cluster of University of Rochester

10.        Chen, G., Znosko, B.M., Kennedy, S.D., Jiao, X., Krugh, T.R., and Turner, D.H. (October 2005, Poster) Improved Thermodynamic Model for Predicting RNA 3 × 3 Internal Loops and NMR Structure of an Unusually Stable Loop with Three Consecutive Sheared GA Pairs.  Upstate New York NMR Symposium, Cornell University

11.        Wood, A., Chen, G., Krugh, T.R., and Turner D.H. (March 2005, Poster)  Thermodynamic Stability of Tetramer RNA Sequences in the Presence of Various Metal Cations.  American Chemical Society National Meeting, San Diego, CA

12.        Chen, G., Znosko, B.M., Kennedy, S.D., Jiao, X., Krugh, T.R., and Turner, D.H. (September 2004, Talk) Thermodynamics and NMR of 3 × 3 Internal Loops in RNA.  Biological Chemistry Cluster, University of Rochester

13.        Chen, G., Znosko, B.M., Kennedy, S.D., Jiao, X., Krugh, T.R., and Turner, D.H. (August 2004, Poster) Improved Thermodynamic Model for Predicting RNA 3 × 3 Internal Loops and NMR Structure of an Unusually Stable Loop with Three Consecutive Sheared GA Pairs.  Biological Chemistry Cluster, University of Rochester

14.        Wood, A., Chen, G., Krugh, T.R., and Turner D.H. (August 2004, Poster) Thermodynamic Stability of Tetramer RNA Sequences in the Presence of Various Metal Cations.  NSF Research Experiences for Undergraduates program, University of Rochester