NATURAL PRODUCT SYNTHESIS


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"Total Synthesis of Swinholide A: An Exposition in Hydrogen-Mediated C-C Bond Formation," Shin, I.; Hong, S.; Krische, M. J. J. Am. Chem. Soc. 2016, 138, 14246.

http://pubs.acs.org/doi/pdf/10.1021/jacs.6b10645

"Evaluation of Chromane-Based Bryostatin Analogues Prepared via Hydrogen-Mediated C-C Bond Formation: Potency Does Not Confer Bryostatin-Like Biology," Ketcham, J. M.; Volchkov, I.; Chen, T.-Y.; Blumberg, P. M.; Kedei, N.; Lewin, N. E.; Krische, M. J. J. Am. Chem. Soc. 2016, 138, 13415.

http://pubs.acs.org/doi/pdf/10.1021/jacs.6b08695

"Total Synthesis of Oridamycin A, Triptoquinone B and C and Isoiresin via Catalytic Enantioselective Formation of All-Carbon Quaternary Centers: Modular Terpenoid Construction," Feng, J.; Noack, F.; Krische, M. J. J. Am. Chem. Soc. 2016, 138, 12364.

http://pubs.acs.org/doi/pdf/10.1021/jacs.6b08902

"Total Synthesis of (+)-SCH 351448 via Transfer Hydrogenative C-C Coupling: Efficiency via Chemoselectivity and Redox-Economy Powered by Metal Catalysis," Wang, G.; Krische, M. J. J. Am. Chem. Soc. 2016, 138, 8088.

http://pubs.acs.org/doi/pdf/10.1021/jacs.6b04917

"Enantioselective Alcohol C-H Functionalization for Polyketide Construction: Unlocking Redox-Economy and Site-Selectivity for Ideal Chemical Synthesis," Feng, J.; Kasun, Z. A.; Krische, M. J. J. Am. Chem. Soc. 2016, 138, 5467 (Perspective Article).

http://pubs.acs.org/doi/pdf/10.1021/jacs.6b02019

"Total Synthesis of Cryptocaryol A via Enantioselective Iridium Catalyzed Alcohol C-H Allylation," Perez, F.; Waldeck, A. R.; Krische, M. J. Angew. Chem. Int. Ed. 2016, 55, 5049.

http://onlinelibrary.wiley.com/doi/10.1002/anie.201600591/abstract;jsessionid=1C84F1CA9136A00E4EBB5DBB7E03795D.f04t01

"Formal Synthesis of Premisakinolide A and C(19)-C(32) of Swinholide A via Site-Selective C-H Allylation and Crotylation of Unprotected Diols," Shin, I.; Krische, M. J. Org. Lett. 2015, 17, 4686.

http://pubs.acs.org/doi/pdf/10.1021/acs.orglett.5b02056

"Direct Generation of Triketide Stereopolyads via Merged Redox-Construction Events: Total Synthesis of (+)-Zincophorin Methyl Ester," Kasun, Z. A.; Gao, X.; Lipinski, R. M.; Krische, M. J. J. Am. Chem. Soc. 2015, 137, 8900.

http://pubs.acs.org/doi/pdf/10.1021/jacs.5b05296

“Synthesis of seco-B-Ring Bryostatin Analogue WN-1 via C-C Bond Forming Hydrogenation: Critical Contribution of the B-Ring in Determining Bryostatin- and PMA-Like Properties,” Andrews, Ian P.; Ketcham, J. M.; Blumberg, P. M.; Kedei, N.; Lewin, N. E.; Krische, M. J. J. Am. Chem. Soc. 2014, 136, 13209. 

http://pubs.acs.org/doi/pdf/10.1021/ja507825s

“Polyketide Construction via Hydrohydroxyalkylation and Related Alcohol CH Functionalizations: Reinventing the Chemistry of Carbonyl Addition,” Dechert-Schmitt, A.-M. R.; Schmitt, D. C.; Gao, X.; Itoh, T.; Krische, M. J. Nat. Prod. Rep. 2014, 31, 504.

http://pubs.rsc.org/en/content/articlelanding/2014/np/c3np70076c

“Asymmetric Alcohol C-H Allylation and syn-Crotylation: C9-C20 of Tetrafibricin,” Itoh, T.; Montgomery, T. P.; Recio, A., III; Krische, M. J. Org. Lett. 2014, 16, 820.

http://pubs.acs.org/doi/pdf/10.1021/ol403566w

“Total Synthesis of (+)-Trienomycins A and F via C-C Bond-Forming Hydrogenation and Transfer Hydrogenation,” Del Valle, D. J.; Krische, M. J. J. Am. Chem. Soc. 2013, 135, 10986. 

http://pubs.acs.org/doi/pdf/10.1021/ja4061273

“Total Synthesis of Cyanolide A in the Absence of Protecting Groups, Chiral Auxiliaries or Premetallated Carbon Nucleophiles,” Waldeck, A. R.; Krische, M. J. Angew. Chem. Int. Ed. 2013, 52, 4470. 

“Total Synthesis of 6-Deoxyerythronolide B via C-C Bond-Forming Transfer Hydrogenation,” Gao, X.; Woo, S. K.; Krische, M. J. J. Am. Chem. Soc. 2013, 135, 4223.

http://pubs.acs.org/doi/pdf/10.1021/ja4008722

“Total Synthesis of Bryostatin 7 via C-C Bond Forming Hydrogenation: Merged Redox-Construction Events for Synthetic Efficiency,” Lu, Y.; Woo, S. K.; Krische, M. J. J. Am. Chem. Soc. 2011, 133, 13876. 

http://pubs.acs.org/doi/pdf/10.1021/ja205673e

“C(21)-C(40) of Tetrafibricin via Metal Catalysis: Beyond Stoichiometric Chiral Reagents, Auxiliaries and Premetallated Nucleophiles,” Kumpulainen, E. T. T.; Kang, B.; Krische, M. J. Org. Lett. 2011, 13, 2484.

http://pubs.acs.org/doi/pdf/10.1021/ol200735r

“Total Synthesis of (+)-Roxaticin via C-C Bond Forming Transfer Hydrogenation: A Departure from Stoichiometric Chiral Reagents, Auxiliaries and Premetallated Nucleophiles in Polyketide Construction,” Han, S. B.; Hassan, A.; Kim, I. S.; Krische, M. J. J. Am. Chem. Soc. 2010, 132, 15559. 

http://pubs.acs.org/doi/abs/10.1021/ja1082798

“Synthesis of the Cytotrienin A Core via Metal Catalyzed C-C Coupling,” Rossle, M.; Del Valle, D. J.; Krische, M. J. Org. Lett. 2011, 13, 1482. 

http://pubs.acs.org/doi/pdf/10.1021/ol200160p

“Concise Synthesis of the Bryostatin A-Ring via Consecutive C-C Bond Forming Transfer Hydrogenations,” Lu, Y.; Krische, M. J. Org. Lett. 2009, 11, 3108. 

http://pubs.acs.org/doi/pdf/10.1021/ol901096d

"Asymmetric Total Synthesis of the Iridoid -Glucoside (+)-Geniposide via Phosphine Organocatalysis." Jones, R. A.; Krische, M. J. Org. Lett. 2009, 11, 1849.

http://pubs.acs.org/doi/pdf/10.1021/ol900360h

“Enantioselective Reductive Coupling of Alkynes and -Ketoaldehydes via Rhodium-Catalyzed Hydrogenation: An Approach to Bryostatin Substructures,” Cho, C.-W.; Krische, M. J. Org. Lett. 2006, 8, 891. 

http://pubs.acs.org/doi/pdf/10.1021/ol052976s

“Intramolecular Organocatalytic [3+2] Dipolar Cycloaddition:  Stereospecific Cycloaddition and The Total Synthesis of (±)-Hirsutene,” Wang, J.-C.; Krische, M. J. Angew. Chem. Int. Ed. 2003, 42, 5855. 

“Catalytic Crossed Michael Cycloisomerization of Thioenoates: Total Synthesis of ()-Ricciocarpin A,” Agapiou, K.; Krische, M. J. Org. Lett. 2003, 5, 1737. 

http://pubs.acs.org/doi/pdf/10.1021/ol030035e

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