H2-MEDIATED C-C COUPLING

"Catalytic Enantioselective Carbonyl Allylation and Propargylation via Alcohol Mediated Hydrogen Transfer: Merging the Chemistry of Grignard and Sabatier," Kim, S. W.; Zhang, W.; Krische, M. J. Acc. Chem. Res. 2017, 50, In Press.

http://pubs.acs.org/doi/pdf/10.1021/acs.accounts.7b00308

"Enantioselective Formation of CF3-Bearing All-Carbon Quaternary Stereocenters via C-H Functionalization of Methanol: Iridium Catalyzed Allene Hydrohydroxymethylation," Holmes, M. T.; Nguyen, K. D.; Schwartz, L. A.; Luong, T.; Krische, M. J. J. Am. Chem. Soc. 2017, 139, 8114.

http://pubs.acs.org/doi/abs/10.1021/jacs.7b04374

"Nickel Catalyzed Cross-Coupling of Vinyl-Dioxanones to Form Enantiomerically Enriched Cyclopropanes," Guo, Y.-A.; Liang, T.; Kim, S. W.; Xiao, H.; Krische, M. J. J. Am. Chem. Soc. 2017, 139, 6847.

http://pubs.acs.org/doi/pdf/10.1021/jacs.7b03371

"Asymmetric Allylation of Glycidols Mediated by Allyl Acetate via Iridium Catalyzed Hydrogen Transfer," Kim, S. W.; Lee, W.; Krische, M. J. Org. Lett. 2017, 19, 1252.

"Ruthenium(0) Catalyzed C-C Coupling of Alkynes and 3-Hydroxy-2-oxindoles: Direct C-H Vinylaion of Alcohols," Luong, T.; Chen, S.; Qu, K.; McInturff, E. L.; Krische, M. J. Org. Lett. 2017, 19, 966.

"Diastereo- and Enantioselective Synthesis of Oxetanes Bearing All-Carbon Quaternary Stereocenters via Iridium Catalyzed Alcohol-Vinyl Epoxide C-C Coupling," Guo, Y.-A.; Lee, W.; Krische, M. J. Chem. Eur. J. 2017, 2557. 

http://onlinelibrary.wiley.com/doi/10.1002/chem.201606046/epdf

"Diols, α-Ketols and Diones as 22π Components in [2+2+2] Cycloadditions of 1,6-Diynes via Ruthenium(0) Catalyzed Transfer Hydrogenation," Sato, H.; Bender, M.; Chen, W.; Krische, M. J. J. Am. Chem. Soc. 2016, 138, 16244.

http://pubs.acs.org/doi/pdf/10.1021/jacs.6b11746

"Metal-Catalyzed Reductive Coupling of Olefin-Derived Nucleophiles: Reinventing Carbonyl Addition," Nguyen, K. D.; Park, B. Y.; Luong, T.; Sato, H.; Garza, V. J.; Krische, M. J. Science 2016, 354, 300.

http://science.sciencemag.org/content/354/6310/aah5133.full

"Regioselective Hydrohydroxy of Styrene with Primary Alcohols or Aldehydes via Ruthenium Catalyzed C-C Bond Forming Transfer Hydrogenation," Xiao, H.; Wang, G.; Krische, M. J. Angew. Chem. Int. Ed. 2016, 55, 16119.

http://onlinelibrary.wiley.com/doi/10.1002/anie.201609056/full

"Osmium(0) Catalyzed C-C Coupling of Ethylene and α-Olefins with Diols, Ketols or Hydroxy Esters via Transfer Hydrogenation," Park, B. Y.; Luong, T.; Sato, H.; Krische, M. J. J. Org. Chem. 2016, 81, 8585.

http://pubs.acs.org/doi/pdf/10.1021/acs.joc.6b01923

"Enantioselective Formation of All-Carbon Quaternary Centers via C-H Functionalization of Methanol: Iridium-Catalyzed Diene Hydrohydroxymethylation," Nguyen, K. D.; Herkommer, D.; Krische, M. J. J. Am. Chem. Soc. 2016, 138, 14210.

http://pubs.acs.org/doi/pdf/10.1021/jacs.6b09333

"C-Propargylation Overrides O-Propargylation in Reactions of Propargyl Chloride with Primary Alcohols: Rhodium Catalyzed Transfer Hydrogenation," Liang, T.; Woo, S. K.; Krische, M. J. Angew. Chem. Int. Ed. 2016, 55, 9207.

http://onlinelibrary.wiley.com/doi/10.1002/anie.201603575/full

"Ruthenium-BINAP Catalyzed Alcohol C-H tert-Prenylation via 1,3-Enyne Transfer Hydrogenation: Beyond Stoichiometric Carbanions in Enantioselective Carbonyl Propargylation," Nguyen, K. D.; Herkommer, D.; Krische, M. J. J. Am. Chem. Soc. 2016, 138, 5238.

http://pubs.acs.org/doi/pdf/10.1021/jacs.6b02279

”Hydroxymethylation beyond Carbonylation: Enantioselectvie Iridium Catalyzed Reductive Coupling of Formaldehyde with Allylic Acetates via Enantiotopic π-Facial Discrimination,” Garza, V. J.; Krische, M. J. J. Am. Chem. Soc. 2016, 138, 3655.

http://pubs.acs.org/doi/pdf/10.1021/jacs.6b01078

"Ruthenium(0)-Catalyzed [4+2] Cycloaddition of Acetylenic Aldehydes with α-Ketols: Convergent Construction of Angucycline Ring Systems," Saxena, A.; Perez, F.; Krische, M. J. Angew. Chem. Int. Ed. 2016, 55, 1493.

http://onlinelibrary.wiley.com/doi/10.1002/anie.201509646/epdf

“Diene Hydroaminomethylation via Ruthenium-Catalyzed C-C Bond Forming Transfer Hydrogenation: Beyond Carbonylation,” Oda, S.; Franke, J.; Krische, M. J. Chem. Sci. 20167, 136.

http://pubs.rsc.org/en/content/articlepdf/2016/sc/c5sc03854e

"Iridium Catalyzed C-C Coupling of a Simple Propargyl Ether with Primary Alcohols: Enantioselective Homoaldol Addition via Redox-Triggered (Z)-Siloxyallylation," Liang, T.; Zhang, W.; Krische, M. J. J. Am. Chem. Soc. 2015, 137, 16024.

http://pubs.acs.org/doi/pdf/10.1021/jacs.5b12131

"Ruthenium Catalyzed Diastereo- and Enantioselevtive Couping of Propargyl Ethers with Alcohols: Siloxy-Crotylation via Hydride Shift Enabled Conversion of Alkynes to π-Allyls," Liang, T.; Zhang, W.; Chen, T.-Y.; Nguyen, K. D.; Krische, M. J.  J. Am. Chem. Soc2015137, 13066.

http://pubs.acs.org/doi/pdf/10.1021/jacs.5b08019
"Diastereo- and Enantioselective Iridium Catalyzed Carbonyl (α-Cyclopropyl)allylation via Transfer Hydrogenation," Tsutsumi, R.; Hong, S.; Krische, M. J. Chem. Eur. J. 2015, 21, 12903. 
http://onlinelibrary.wiley.com/doi/10.1002/chem.201502499/epdf

"Diastereo- and Enantioselective Iridium Catalyzed Coupling of Vinyl Aziridines and Alcohols: SIte-Selective Modification of Unprotected Diols and Synthesis of Substituted Piperidines," Wang, G.; Franke, J.; Ngo, C. Q.; Krische, M. J. J. Am. Chem. Soc2015137, 7915.

http://pubs.acs.org/doi/pdf/10.1021/jacs.5b04404
"A Metallacycle Fragmentation Strategy for Vinyl Transfer from Enol Carboxylates to Secondary Alcohol C-H Bonds via Osmium or Ruthenium Catalyzed  Transfer Hydrogenation," Park, B. Y.; Luong, T.; Sato, H.; Krische, M. J. J. Am. Chem. Soc2015137, 7652.
http://pubs.acs.org/doi/pdf/10.1021/jacs.5b04688

"Ruthenium(0) Catalyzed Endiyne-α-Ketol [4+2] Cycloaddition: Convergent Assembly of Type II Polyketide Substructures," Saxena, A.; Perez, F.; Krische, M. J. J. Am. Chem. Soc. 2015, 137, 5883.

http://pubs.acs.org/doi/pdf/10.1021/jacs.5b02755

“Enantioselective Ruthenium Catalyzed Carbonyl Allylation via Alkyne-Alcohol C-C Bond Forming Transfer Hydrogenation: Allene Hydrometallation vs. Oxidative Coupling,” Liang, T.; Nguyen, K. D.; Zhang, W.; Krische, M. J. J. Am. Chem. Soc. 2015, 137, 3164.

http://pubs.acs.org/doi/pdf/10.1021/jacs.5b00747

"Hydroaminomethylation Beyond Carbonylation: Allene-Imine Reductive Coupling by Ruthenium-Catalyzed Transfer Hydrogenation," Oda, S.; Sam, B.; Krische, M. J. Angew. Chem. Int. Ed. 2015, 54, 8525.

http://onlinelibrary.wiley.com/doi/10.1002/anie.201503250/epdf

“Ruthenium Catalyzed C-C Coupling of Fluorinated Alcohols with Allenes to Form All-Carbon Quaternary Centers: Dehydrogenation at the Energetic Limit of β-Hydride Elimination,” Sam, B.; Luong, T.; Krische, M. J. Angew. Chem. Int. Ed. 2015, 54, 5465 

http://onlinelibrary.wiley.com/doi/10.1002/anie.201500238/pdf

“Ruthenium Catalyzed C-C Coupling of Amino Alcohols with Dienes via Transfer Hydrogenation: Redox-Triggered Imine Addition and Related Hydroaminoalkylations,” Chen, T.-Y.; Tsutsumi, R.; Montgomery, T. P.; Volchkov, I. Krische, M. J. J. Am. Chem. Soc. 2015, 137, 1798.

http://pubs.acs.org/doi/pdf/10.1021/ja5130258

"Palladium Catalyzed Reductive Cyclization of N-Acyl ortho-Bromoanilides to Form 3-Hydroxy-2-Oxindoles: A Hydrogen-Mediated Grignard Addition," Shin, I.; Ramgren, S. D.; Krische, M. J. Tetrahedron 2015, 71, 5776.

http://www.sciencedirect.com/science/article/pii/S0040402015007929

“Catalyst-Directed Diastereo- and Site-Selectivity in Successive Nucleophilic and Electrophilic Allylations of Chiral 1,3-Diols: Protecting Group-Free Synthesis of 4-Hydroxy-2,6-cis- or trans-Pyrans,” Shin, I.; Wang, G.; Krische, M. J. Chem. Eur. J. 2014, 13382.

http://onlinelibrary.wiley.com/doi/10.1002/chem.201404065/abstract

“Alkynes as Allylmetal Equivalents in Redox-Triggered C-C Couplings to Primary Alcohols: (Z)-Homoallylic Alcohols via Ruthenium Catalyzed Propargyl C-H Activation,” Park, B. Y.; Nguyen, K. D.; Chaulagain, M. R.; Komanduri, V.; Krische, M. J. J. Am. Chem. Soc. 2014, 136, 11902.

http://pubs.acs.org/doi/pdf/10.1021/ja505962w

“Redox-Triggered C-C Coupling of Alcohols and Vinyl Epoxides: Diastereo- and Enantioselective Formation of All-Carbon Quaternary Centers via tert-(Hydroxy)-Prenylation,” Feng, J.; Garza, V. J.; Krische, M. J. J. Am. Chem. Soc. 2014, 136, 8911.

http://pubs.acs.org/doi/pdf/10.1021/ja504625m

“Benzannulation via Ruthenium Catalyzed Diol-Diene [4+2] Cycloaddition: One- and Two-Directional Syntheses of Fluoranthenes and Acenes,” Geary, L. M.; Chen T.-Y.; Montgomery, T. P.; Krische, M. J. J. Am. Chem. Soc. 2014, 136, 5920.

http://pubs.acs.org/doi/pdf/10.1021/ja502659t

“Redox-Triggered C-C Coupling of Diols and Alkynes: Synthesis of β,γ-Unsaturated α-Hydroxyketones and Furans via Ruthenium Catalyzed Hydrohydroxyalkylation,” McInturff, E. L.; Nguyen, K. D.; Krische, M. J. Angew. Chem. Int. Ed. 2014, 53, 3232.

http://onlinelibrary.wiley.com/doi/10.1002/anie.201311130/epdf

"Ring Expansion of Cyclic 1,2-Diols to Form Medium Sized Rings via Ruthenium Catalyzed Transfer Hydrogenative Cycloaddition," Kasun, Z. A.; Geary, L. M.; Krische, M. J. Chem. Comm. 2014, 7545.

http://pubs.rsc.org/en/content/articlelanding/2014/cc/c4cc03983a#!divAbstract

“Ruthenium Catalyzed Hydrohydroxyalkylation of Acrylates with Diols and α-Hydroxycarbonyl Compounds to Form Spiro- and α-Methylene-γ-Butyrolactones,” McInturff, E. L.; Mowat, J.; Waldeck, A. R.; Krische, M. J. J. Am. Chem. Soc. 2013, 135, 17230.

http://pubs.acs.org/doi/pdf/10.1021/ja410533y

“Ruthenium Catalyzed Hydrohydroxyalkylation of Isoprene Employing Heteroaromatic Secondary Alcohols: Isolation and Reversible Formation of the Putative Metallacycle Intermediate,” Park, B. Y.; Montgomery, T. P.; Garza, V.; Krische, M. J. J. Am. Chem. Soc. 2013, 135, 16320.

http://pubs.acs.org/doi/pdf/10.1021/ja4087193

“Direct C-C Coupling of α-Olefins and Styrenes to 3-Hydroxy-2-oxindoles by Ruthenium Catalyzed Hydrohydroxyalkylation: Byproduct-Free Conversion of Secondary to Tertiary Alcohols,” Yamaguchi, E.; Mowat, J.; Luong, T.; Krische, M. J. Angew. Chem. Int. Ed. 2013, 52, 8428.

http://onlinelibrary.wiley.com/doi/10.1002/anie.201303552/epdf

“Ruthenium Catalyzed Reductive Coupling of Paraformaldehyde to Trifluoromethyl Allenes: CF3-Bearing All-Carbon Quaternary Centers,” Sam, B.; Montgomery, T. P. Krische, M. J. Org. Lett. 2013, 15, 3790.

http://pubs.acs.org/doi/pdf/10.1021/ol401771a

“Ruthenium Catalyzed Hydroaminoalkylation of Isoprene via Transfer Hydrogenation: Byproduct-free Prenylation of Hydantoins,” Schmitt, D. C.; Lee, J.; Dechert-Schmitt, A.-M. R. Yamaguchi, E.; Krische, M. J. Chem. Comm. 2013, 6096.

http://pubs.rsc.org/en/content/articlepdf/2013/cc/c3cc43463j

“Successive C-C Coupling of Dienes to Vicinally Dioxygenated Hydrocarbons: Ruthenium Catalyzed [4+2] Cycloaddition across the Diol, Hydroxycarbonyl or Dione Oxidation Levels,” Geary, L. M.; Glasspoole, B. W.; Kim, M. M. Krische, M. J. J. Am. Chem. Soc. 2013, 135, 3796.

http://pubs.rsc.org/en/content/articlepdf/2013/cc/c3cc43463j

“Site-Selective Primary Alcohol Dehydrogenation Enables Protecting Group-Free Diastereoselective C-C Coupling of 1,3-Glycols and Allyl Acetate,” Dechert-Schmitt, A.-M. R.; Schmitt, D. C.; Krische, M. J. Angew. Chem. Int. Ed. 2013, 52, 3195.

"Regioselective Ruthenium Catalyzed Hydrohydorxyalkylation of Dienes with 3-Hydorxy-2-Oxindoles: Prenylation, Geranylation and Beyond," Chen, T.-Y.; Krische, M. J. Org. Lett. 2013, 15, 2994.

http://pubs.acs.org/doi/pdf/10.1021/ol401184k

“Regiodivergent Reductive Coupling of 2-Substituted Dienes to Formaldehyde Employing Ruthenium or Nickel Catalysts: Hydrohydroxymethylation via Transfer Hydrogenation,” Köpfer, A.; Sam, B.; Breit, B.; Krische, M. J. Chem. Sci. 2012, 4, 1876.

http://pubs.rsc.org/en/content/articlepdf/2013/sc/c3sc22051f?page=search

“Chiral Anion Dependent Inversion of Diastereo- and Enantioselectivity in Carbonyl Crotylation via Ruthenium Catalyzed Butadiene Hydrohydroxyalkylation,” McInturff, E. L.; Yamaguchi, E.; Krische, M. J. J. Am. Chem. Soc. 2012, 134, 20628.

http://pubs.acs.org/doi/pdf/10.1021/ja311208a

“Iridium-Catalyzed Allylation of Chiral β-Stereogenic Alcohols: Bypassing Discrete Formation of Epimerizable Aldehydes,” Org. Lett. Schmitt, D. C.; Dechert-Schmitt, A.-M. R.; Krische, M. J. Org. Lett. 2012, 14, 6302. 

http://pubs.acs.org/doi/pdf/10.1021/ol3030692

“Direct, Redox Neutral Prenylation and Geranylation of Secondary Carbinol C-H Bonds: C4 Regioselectivity in Ruthenium Catalyzed C-C Couplings of Dienes to α-Hydroxy Esters,” Leung, J. C.; Geary, L. M.; Chen, T.-Y.; Zbieg, J. R.; Krische, M. J. J. Am. Chem. Soc. 2012, 134, 15700. 

http://pubs.acs.org/doi/pdf/10.1021/ja3075049

“Ruthenium Catalyzed Reductive Coupling of 1,3-Enynes and Aldehydes via Transfer Hydrogenation: anti-Diastereoselective Carbonyl Propargylation,” Geary, L. M.; Leung, J. C.; Krische, M. J. Chem. Eur. J. 2012, 18, 16823. 

“Enantioselective Conversion of Primary Alcohols to α-Methylene Butyrolactones via Iridium Catalyzed C-C Bond Forming Transfer Hydrogenation: 2-(Alkoxycarbonyl)allylation,” Montgomery, T. P.; Hassan, A.; Park, B. Y.; Krische, M. J. J. Am. Chem. Soc. 2012, 134, 11100. 

http://pubs.acs.org/doi/pdf/10.1021/ja303839h

“Enantioselective Carbonyl Propargylation by Iridium-Catalyzed Transfer Hydrogenative Coupling of Alcohols and Propargyl Chlorides,” Woo, S. K.; Geary, L. M.; Krische, M. J. Angew. Chem. Int. Ed. 2012, 51, 7830. 

“Consecutive Iridium Catalyzed C-C and C-H Bond Forming Hydrogenations for the Diastereo- and Enantioselective Synthesis of syn-3-Fluoro-1-Alcohols: C-H (2-Fluoro)allylation of Primary Alcohols,” Hassan, A.; Montgomery, T. P.; Krische, M. J. Chem. Comm. 2012, 4692. 

http://pubs.rsc.org/en/content/articlepdf/2012/cc/c2cc31743e?page=search

“Enantioselective C-H Crotylation of Primary Alcohols via Hydrohydroxyalkylation of Butadiene,” Zbieg, J. R.; Yamaguchi, E.; McInturff, E. L.; Krische, M. J. Science 2012, 336, 324. 

http://www.sciencemag.org/content/336/6079/324.full.pdf?sid=ea47e269-f3f5-4b33-9d3b-fd9c8fd2c3ac

“Diastereo- and Enantioselective Iridium Catalyzed Carbonyl Propargylation from the Alcohol or Aldehyde Oxidation Level: 1,3-Enynes as Allenylmetal Equivalents,” Geary, L. M.; Woo, S. K.; Leung, J. C. Krische, M. J. Angew. Chem. Int. Ed. 2012, 51, 2972. 

“Polarity Inversion of Donor-Acceptor Cyclopropanes: Disubstituted -Lactones via Enantioselective Iridium Catalysis,” Moran, J.; Smith, A. G.; Carris, R. M.; Johnson, J. S.; Krische, M. J. J. Am. Chem. Soc. 2011, 133, 18618. 

http://pubs.acs.org/doi/pdf/10.1021/ja2090993

“Direct Generation of Acyclic Polypropionate Stereopolyads via Double Diastereo- and Enantioselective Iridium Catalyzed Crotylation of 1,3-Diols: Beyond Stepwise Carbonyl Addition in Polyketide Construction,” Gao, X.; Han, H.; Krische, M. J. J. Am. Chem. Soc. 2011, 133, 12795. 

“Alkyne-Aldehyde Reductive C-C Coupling via Ruthenium Catalyzed Transfer Hydrogenation: Regio- and Stereoselective Carbonyl Vinylation to Form Trisubstituted Allylic Alcohols in the Absence of Vinylmetal Reagents,” Leung, J. C.; Patman, R. L.; Sam, B.; Krische, M. J. Chem. Eur. J. 2011, 17, 12437.

“Catalytic Enantioselective Grignard Nozaki-Hiyama Methallylation from the Alcohol Oxidation Level: Chloride Compensates for π-Complex Instability,” Hassan, A.; Townsend, I. A.; Krische, M. J. Chem. Comm. 2011, 10028.

http://pubs.rsc.org/en/content/articlelanding/2011/CC/C1CC14392A#!divAbstract

“Diastereo- and Enantioselective Ruthenium Catalyzed Hydrohydroxyalkylation of 2-Silyl-Butadienes: Carbonyl syn-Crotylation from the Alcohol Oxidation Level,” Zbieg, J. R.; Moran, J.; Krische M. J. J. Am. Chem. Soc. 2011, 133 (27), 10582.

http://pubs.acs.org/doi/abs/10.1021/ja2046028

"Divergent Regioselectivity in the Synthesis of Trisubstituted Allylic Alcohols by Nickel- and Ruthenium-Catalyzed Alkyne Hydroxymethylation with Formaldehyde," Bausch, C. C.; Patman, R. L.; Breit, B.; Krische, M. J. Angew. Chem. Int. Ed. 2011, 50, 5687.

http://onlinelibrary.wiley.com/doi/10.1002/anie.201101496/epdf

“Iridium Catalyzed anti-Diastereo- and Enantioselective Carbonyl (α-Trifluoromethyl)allylation from the Alcohol or Aldehyde Oxidation Level,” Gao, X.; Zhang, Y. J.; Krische, M. J. Angew. Chem. Int. Ed. 2011, 50, 4173.

“Enantioselective Iridium Catalyzed Vinylogous Reformatsky-Aldol Reaction from the Alcohol Oxidation Level: Linear Regioselectivity by Way of Carbon-Bound Enolates,” Zbieg, J. R.; Hassan, A.; Kim, I.-S.; Krische, M. J. Angew. Chem. Int. Ed. 2011, 50, 3493. 

http://onlinelibrary.wiley.com/doi/10.1002/anie.201100646/epdf

“Amplification of anti-Diastereoselectivity via Curtin-Hammett Effects in Ruthenium Catalyzed Hydrohydroxyalkylation of 1,1-Disubstituted Allenes: Diastereoselective Formation of All-Carbon Quaternary Centers,” Zbieg, J. R.; McIntuff, E. L.; Leung, J. C.; Krische, M. J. J. Am. Chem. Soc. 2011, 133, 1141. 

http://pubs.acs.org/doi/abs/10.1021/ja1104156?prevSearch=%2528krische%2529%2BAND%2B%255Bauthor%253A%2BKrische%252C%2BMichael%2BJ.%255D%2BNOT%2B%255Batype%253A%2Bad%255D%2BNOT%2B%255Batype%253A%2Bacs-toc%255D&searchHistoryKey=

"Direct Catalytic C-C Coupling of Methanol Employing a Homogeneous Iridium Complex: Hydrohydroxymethylation of Allenes," Moran, J.; Preetz, A.; Mesch, R. A.; Krische, M. J. Nature Chem. 2011, 3, 287.

http://www.nature.com/nchem/journal/v3/n4/full/nchem.1001.html

"Enhanced anti-Diastereo- and Enantioselectivity in Alcohol Mediated Carbonyl Crotylation Using an Isolable Single Component Iridium Catalyst," Gao, X.; Townsend, I. A.; Krische, M. J. J. Org. Chem. 2011, 76, 2350.

http://pubs.acs.org/doi/pdf/10.1021/jo200068q

“Total Synthesis of (+)-Roxaticin via C-C Bond Forming Transfer Hydrogenation: A Departure from Stoichiometric Chiral Reagents, Auxiliaries and Premetallated Nucleophiles in Polyketide Construction,” Han, S. B.; Hassan, A.; Kim, I. S.; Krische, M. J. J. Am. Chem. Soc. 2010, 132, 15559. 

http://pubs.acs.org/doi/abs/10.1021/ja1082798

"Iridium Catalyzed anti-Diastereo- and Enantioselective Carbonyl (Trimethylsilyl)allylation from the Alcohol or Aldehyde Oxidation Level" Han, S. B.; Gao, X.; Krische, M. J. J. Am. Chem. Soc. 2010, 132, 9153.

http://pubs.acs.org/doi/abs/10.1021/ja103299f

"Direct Ruthenium Catalyzed C-C Coupling of Ethanol: Diene Hydro-Hydroxyethylation to Form All Carbon Quaternary Center" Han, H.; Krische, M. J. Org. Lett. 2010, 12, 2844.

http://pubs.acs.org/doi/abs/10.1021/ol101077v

"Allenamide Hydro-Hydroxyalkylation: 1,2-Aminoalcohols via Ruthenium Catalyzed Carbonyl anti-Aminoallylation" Zbieg, J. R.; McInturff, E.; Krische, M. J. Org. Lett. 2010, 12, 2514.

http://pubs.acs.org/doi/abs/10.1021/ol1007235

"anti-Diastereo- and Enantioselective Carbonyl (Hydroxymethyl)allylation from the Alcohol or Aldehyde Oxidation Level: Allyl Carbonates as Allylmetal Surrogates" Zhang, Y. J.; Yang, J. H.; Kim, S. H.; Krische, M. J. J. Am. Chem. Soc. 2010, 132, 4562.

http://pubs.acs.org/doi/abs/10.1021/ja100949e

"Diastereo- and Enantioselective anti-Alkoxyallylation Employing Allylicgem-Dicarboxylate as Ally Donors via Iridium Catalyzed Transfer Hydorgenation." Han, S. B.; Han, H.; Krische, M. J. J. Am. Chem. Soc. 2010, 132, 1760.

http://pubs.acs.org/doi/abs/10.1021/ja9097675

"All Carbon Quaternary Centers via Ruthenium Catalyzed Hydroxymethylation of 2-Substituted Butadiene Mediated by Formaldehyde: Beyond Hydroformylation." Smejkal, T.; Han, H.; Breit, B.; Krische, M. J. J. Am. Chem. Soc. 2009, 131, 10366.

http://pubs.acs.org/doi/abs/10.1021/ja904124b

"Enantioselective Allylation Crotylation and Reverse Prenylation of Substituted Isatin via Iridium Catalyzed C-C Bond Forming Transfer Hydrogenation." Itoh, J.; Han, S. B.; Krische, M. J. Angew. Chem. Int. Ed. 2009, 48, 6313.

http://onlinelibrary.wiley.com/doi/10.1002/ange.200902328/full

"Elongation of 1,3-Polyols via Iterative Catalyst-Directed Carbonyl Allylation from the Alcohol Oxidation Level." Hassan, A.; Lu, Y.; Krische, M. J. Org. Lett. 2009, 11, 3112.

http://pubs.acs.org/doi/abs/10.1021/ol901136w

"1,n-Glycols as Dialdehyde Equivalents in Iridium Catalyzed Enantioselective Carbonyl Allylation and Iterative Two-Directional Assembly of 1,3-Polyols." Lu, Y.; Kim, I.-S.; Hassan, A.; Del Valle, D. J.; Krische, M. J. Angew. Chem. Int. Ed. 2009, 48, 5018.

http://onlinelibrary.wiley.com/doi/10.1002/anie.200901648/abstract?systemMessage=Wiley+Online+Library+will+be+disrupted+14+May+from+10-12+BST+for+monthly+maintenance

"Enantioselective Carbonyl Reverse Prenylation from the Alcohol or Aldehyde Oxidation Level Employing 1,1-Dimethylallene as the Prenyl Donor." Han, S. B.; Kim, I.-S.; Han, H.; Krische, M. J. J. Am. Chem. Soc. 2009, 131, 6916.

http://pubs.acs.org/doi/abs/10.1021/ja902437k

"anti-Aminoallylation of Aldehydes via Ruthenium Catalyzed Transfer Hydrogenative Coupling of Sulfonamido Allenes: 1,2-Aminoalcohols ." Skucas, E.; Zbieg, J. R.; Krische, M. J. J. Am. Chem. Soc. 2009, 131, 5054.

http://pubs.acs.org/doi/abs/10.1021/ja900827p

"Direct C-Vinylation of Alcohols or Aldehydes Employing Alkynes as Vinyl Donors: A Ruthenium Catalyzed C-C Bond Forming Transfer Hydrogenation." Patman, R. L.; Chaulagain, M. R.; Williams, V. M.; Krische, M. J. J. Am. Chem. Soc. 2009, 131, 2066.

http://pubs.acs.org/doi/abs/10.1021/ja809456u

"anti-Diastereo- and Enantioselective Carbonyl Crotylation from the Alcohol or Aldehyde Oxidation Level Employing a Cyclometallated Iridium Catalyst: a-Methyl Allyl Acetate as a Surrogate to Preformed Crotylmetal Reagent." Kim, I. S.; Han, S. B.; Krische, M. J. J. Am. Chem. Soc. 2009, 131, 2514.

http://pubs.acs.org/doi/abs/10.1021/ja808857w

"Hydroacylation of 2-Butyne from the Alcohol or Aldehyde Oxidation Level via Ruthenium Catalyzed C-C Bond Forming Transfer Hydrogenation." Williams, V. M.; Leung, J. C.; Patman, R. L.; Krische, M. J. Tetrahedron 2009, 65, 5024.

http://www.sciencedirect.com/science/article/pii/S0040402009004633
 "Enantioselective Iridium Catalyzed Carbonyl Allylation from the Alcohol or Aldehyde Oxidation Level via Transfer Hydrogenative Coupling of Allyl Acetate: Departure from Chirally Modified Allyl Metal Reagents in Carbonly Addition." Kim, I. S.; Nagi, M. -Y.; Krische, M. J. J. Am. Chem. Soc. 2008, 130, 14891.
http://pubs.acs.org/doi/abs/10.1021/ja805722e

"Diene Hydroacylation from the Alcohol or Aldehyde Oxidation Level via Ruthenium-Catalyzed C-C Bond-Forming Transfer Hydrogenation: Synthesis of β,γ-Unsaturated Ketones." Shibahara, F.; Bower, J. F.; Krische, M. J. J. Am. Chem. Soc. 2008, 130, 14120.

http://pubs.acs.org/doi/abs/10.1021/ja805356j

"Branch-Selective Reductive Coupling of 2-Vinyl Pyridines and Imines via Rhodium Catalyzed C-C Bond Forming Hydrogenation." Komanduri. V.;Grant, C. D.; Krische, M. J. J. Am. Chem. Soc. 2008, 130, 12592.

http://pubs.acs.org/doi/abs/10.1021/ja805056g

"Catalyst-Directed Diastereoselectivity in Hydrogenative Coupling of Acetylene to α-Chiral Aldehydes: Formal Synthesis of All Eight L-Hexoses." Han, S. B.; Kong, J.-R.; Krische, M. J. Org. Lett. 2008, 10, 4133.

http://pubs.acs.org/doi/abs/10.1021/ol8018874

"Ruthenium Catalyzed C-C Bond Formation via Transfer Hydrogenation: Branch-Selective Reductive Coupling of Allenes to Paraformaldehyde and Higher Aldehydes." Ngai, M. -Y.; Skucas, E.; Krische, M. J. Org. Lett. 2008, 10, 2705.

http://pubs.acs.org/doi/abs/10.1021/ol800836v

"Carbonyl Propargylation from the Alcohol or Aldehyde Oxidation Level Employing 1,3-Enynes as Surrogates to Preformed Allenylmetal Reagents: A Ruthenium Catalyzed C-C Bond Forming Transfer Hydrogenation." Patman, R. L.; Williams, V. M.; Bower, J. F.; Krische, M. J. Angew. Chem. Int. Ed. 2008, 47, 5220.

http://onlinelibrary.wiley.com/doi/10.1002/anie.200801359/abstract?systemMessage=Wiley+Online+Library+will+be+disrupted+14+May+from+10-12+BST+for+monthly+maintenance

"Enantioselective Iridium Catalyzed Carbonyl Allylation from the Alcohol or Aldehyde Oxidation Level Using Allyl Acetate as an Allyl Metal Surrogate." Kim, I. S.; Ngai, M, -Y.;  Krische, M. J. J. Am. Chem. Soc. 2008, 130, 6340.

http://pubs.acs.org/doi/abs/10.1021/ja802001b

"Ruthenium Catalyzed C-C Bond Forming Transfer Hydrogenation: Carbonyl Allylation from the Alcohol or Aldehyde Oxidation Level Employing Acyclic 1,3-Dienes as Surrogates to Preformed Allyl Metal Reagents." Shibahara, F.; Bower, J. F.;  Krische, M. J. J. Am. Chem. Soc. 2008, 130, 6338.

http://pubs.acs.org/doi/abs/10.1021/ja801213x

"Diastereo- and Enantioselective Hydrogenative Aldol Coupling of Vinyl Ketones: Design of an Effective Monodentate TADDOL-Like Phosphonite Ligand." Bee C.; Han, S. B.; Hassan, A.; Ioda, H.;  Krische, M. J. J. Am. Chem. Soc. 2008, 130, 2746.

http://pubs.acs.org/doi/abs/10.1021/ja710862u

"Iridium Catalyzed C-C Coupling via Transfer Hydrogenation: Carbonyl Addition from the Alcohol or Aldehyde Oxidation Level Employing 1,3-Cyclohexadiene." Bower, J. F.; Patman, R. L.; Krische, M. J. Org. Lett. 2008, 10, 1033. 

http://pubs.acs.org/doi/abs/10.1021/ol800159w

"Catalytic C-C Coupling via Transfer Hydrogenation: Reverse Prenylation, Crotylation and Allylation from the Alcohol or Aldehyde Oxidation Level." Bower, J.; Skucas, E.; Patman, R. L.; Krische, M. J. J. Am. Chem. Soc. 2007, 129, 15134.

http://pubs.acs.org/doi/abs/10.1021/ja077389b

"Enantioselective Iridium Catalyzed Imine Vinylation: Optically Enriched Allylic Amines via Alkyne-Imine Reductive Coupling Mediated by Hydrogen." Ngai, M.-Y.; Barchuk, A.; Krische, M. J. J. Am. Chem. Soc. 2007, 129, 12644.

http://pubs.acs.org/doi/abs/10.1021/ja075438e

"Carbonyl Allylation in the Absence of Preformed Allyl Metal Reagents: Reverse Prenylation via Iridium Catalyzed Hydrogenative Coupling of Dimethylallene." Skucas, E.; Bower, J.; Krische, M. J. J. Am. Chem. Soc. 2007, 129, 12678.

http://pubs.acs.org/doi/abs/10.1021/ja075971u

"Enantioselective Reductive Coupling of 1,3-Enynes to Glyoxalates Mediated by Hydrogen: Asymmetric Synthesis of β,γ-Unsaturated α-Hydroxy Esters."  Hong, Y.-T.; Cho, C.-W.; Skucas, E.; Krische, M. J. Org. Lett. 2007, 9, 3745. 

http://pubs.acs.org/doi/abs/10.1021/ol7015548

"Allylic Amine via Iridium Catalyzed C-C Bond Forming Hydrogenation: Imine Vinylation in the Absence of Stoichiometric Byproducts or Metallic Reagents." Barchuk, A.; Ngai, M.-Y.; Krische, M. J. J. Am. Chem. Soc. 2007, 129, 8432.

http://pubs.acs.org/doi/abs/10.1021/ja073018j

"Enantioselective Reductive Coupling of Acetylene to N-Arylsulfonyl Imines via Rhodium Catalyzed C-C Bond Forming Hydrogenation: (Z)-Dienyl Allylic Amines." Skucas, E.; Kong, J.-R.; Krische, M. J. J. Am. Chem. Soc. 2007, 129, 7242.

http://pubs.acs.org/doi/abs/10.1021/ja0715896

"Iridium Catalyzed C-C Bond Forming Hydrogenation: Direct Regioselective Reductive Coupling of Alkyl-Substituted Alkynes to Activated Ketones." Ngai, M.-Y.; Barchuk, A.; Krische, M. J. J. Am. Chem. Soc. 2007, 129, 280.

http://pubs.acs.org/doi/abs/10.1021/ja0670815

"Asymmetric Induction in Hydrogen-Mediated Reductive Aldol Additions to α-Amino Aldehydes Catalyzed by Rhodium: Selective Formation of syn-Stereotriads Directed by Intramolecular Hydrogen-Bonding." Jung, C.-K.; Krische, M. J. J. Am. Chem. Soc. 2006, 128, 17051.

http://pubs.acs.org/doi/abs/10.1021/ja066198q

"Enantioselective Reductive Coupling of 1,3-Enynes to Heterocyclic Aromatic Aldehydes and Ketones via Rhodium Catalyzed Asymmetric Hydrogenation: Mechanistic Insight into the Role of Brønsted Acid Additives." Komanduri, V.; Krische, M. J. J. Am. Chem. Soc. 2006, 128, 16448.

http://pubs.acs.org/doi/abs/10.1021/ja0673027

"Catalytic Carbonyl (Z)-Dienylation via Multicomponent Reductive Coupling of Acetylene to Aldehydes and α-Ketoesters Mediated by Hydrogen: Carbonyl Insertion into Cationic Rhodocyclopentadienes." Kong, J.-R.; Krische, M. J. J. Am. Chem. Soc. 2006, 128, 16040. 

http://pubs.acs.org/doi/abs/10.1021/ja0664786

"Branched-Selective Intermolecular Hydroacylation: Hydrogen-Mediated Coupling of Anhydrides to Styrenes and Activated Olefins." Hong, Y.-T.; Barchuk, A.; Krische, M. J. Angew. Chem. Int. Ed. 2006, 128, 6885.

http://onlinelibrary.wiley.com/doi/10.1002/anie.200602377/abstract;jsessionid=D744A653B817ECCEDBF9A927071D04FD.d01t01?systemMessage=Wiley+Online+Library+will+be+disrupted+14+May+from+10-12+BST+for+monthly+maintenance

"Reductive Aldol Coupling of Divinyl Ketones via Rhodium Catalyzed Hydrogenation: syn-Diastereoselective Construction of  β-Hydroxyenones." Han, S. B.; Krische, M. J. Org. Lett. 2006, 8, 5657.

http://pubs.acs.org/doi/abs/10.1021/ol0624023

"Highly Enantioselective Reductive Cyclization of Acetylenic Aldehydes via Rhodium Catalyzed Asymmetric Hydrogenation." Rhee, J.-U.; Krische, M. J. J. Am. Chem. Soc. 2006, 128, 10674.

http://pubs.acs.org/doi/abs/10.1021/ja0637954

"α-Hydroxy Esters via Enantioselective Hydrogen-Mediated C-C Coupling: Regiocontrolled Reactions of Silyl-Substituted 1,3-Diynes." Cho, C.-W.; Krische, M. J. Org. Lett. 2006, 8, 3873.

http://pubs.acs.org/doi/abs/10.1021/ol061485k

"An Approach to the Bryostatin Recognition Domain via Enantioselective Rhodium Catalyzed Reductive Coupling Mediated by Hydrogen." Cho, C.-W.; Krische, M. J. Org. Lett. 2006, 8, 891.

http://pubs.acs.org/doi/abs/10.1021/ol052976s

"Hydrogen-Mediated Aldol Reductive Coupling of Vinyl Ketones Catalyzed by Rhodium: High Syn-Selectivity through the Effect of Tri-2-furylphosphine," Jung, C.-K.; Garner, S. A.; Krische, M. J. Org. Lett. 2006, 8, 519.

http://pubs.acs.org/doi/abs/10.1021/ol052859x

"Highly Enantioselective Direct Reductive Coupling of Conjugated Alkynes and α-Ketoesters via Rhodium Catalyzed Asymmetric Hydrogenation," Kong, J.-R.; Ngai, M.-Y.; Krische, M. J. J. Am. Chem. Soc. 2006, 128, 718.

http://pubs.acs.org/doi/abs/10.1021/ja056474l

"Hydrogen-Mediated Reductive Coupling of Conjugated Alkynes with Ethyl (N-sulfinyl)iminoacetates: Diastereoselective Synthesis of Unnatural α-Amino Acids via Rhodium Catalyzed C-C Bond Forming Hydrogenation." Kong, J.-R.; Cho, C.-W.; Krische, M. J. J. Am. Chem. Soc. 2005, 127, 11269.

http://pubs.acs.org/doi/abs/10.1021/ja051104i

"Enantioselective Reductive Cyclization of 1,6-Enynes via Rhodium Catalyzed Asymmetric Hydrogenation: C-C Bond Formation Precedes Hydrogen Activation." Jang, H.-Y.; Hughes, F. W.; Gong, H.; Zhang, J.; Brodbelt, J. S.; Krische, M. J. J. Am. Chem. Soc. 2005, 127, 6174.

http://pubs.acs.org/doi/abs/10.1021/ja042645v

"Rhodium Catalyzed Reductive Cyclization of 1,6-Diynes and 1,6-Enynes Mediated by Hydrogen: Catalytic C-C Bond Formation via Capture of Hydrogenation Intermediates." Jang, H.-Y.; Krische, M. J. J. Am. Chem. Soc. 2004, 126, 7875.

http://pubs.acs.org/doi/abs/10.1021/ja048498i

"Hydrogen-Mediated C-C Bond Formation: Catalytic Regio- and Stereoselective Reductive Condensation of α-Keto Aldehydes and 1,3-Enynes." Jang, H.-Y.; Huddleston, R. R.; Krische, M. J. J. Am. Chem. Soc. 2004, 126, 4664.

http://pubs.acs.org/doi/abs/10.1021/ja0316566

"Catalytic Addition of Metallo-Aldehyde Enolates to Ketones: A New C-C Bond Forming Hydrogenation." Koech, P. K.; Krische, M. J. Org. Lett. 2004, 6, 691.

http://pubs.acs.org/doi/abs/10.1021/ol030136c

"Metallo-Aldehyde Enolates via Enal Hydrogenation: Catalytic Cross Aldolization with Glyoxal Partners as Applied to the Synthesis of 3,5-Disubstituted Pyridazines." Marriner, G. A.; Garner, S. A.; Jang, H.-Y.; Krische, M. J. J. Org. Chem. 2004, 69, 1380.

http://pubs.acs.org/doi/abs/10.1021/jo030310a

"First Catalytic Reductive Coupling of 1,3-Diynes to Carbonyl Partners: A New Regio- and Enantioselective C-C Bond Forming Hydrogenation." Huddleston, R. R.; Jang, H.-Y. Krische, M. J. J. Am. Chem. Soc. 2003, 125, 11488.

http://pubs.acs.org/doi/abs/10.1021/ja030415v

"Enolate Generation under Hydrogenation Conditions: Catalytic Aldol Cycloreduction of Keto-Enones." Huddleston, R. R.; Krische, M. J. Org. Lett. 2003, 5, 1143.

http://pubs.acs.org/doi/abs/10.1021/ol0300219

"Use of Elemental Hydrogen for the Reductive Generation of Enolates from Enones: Catalytic C-C Bond Formation under Hydrogenative Conditions." Jang, H.-Y.; Huddleston, R. R.; Krische, M. J. J. Am. Chem. Soc. 2002, 124, 15156.

http://pubs.acs.org/doi/abs/10.1021/ja021163l
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