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Kristin M. Engebretsen


Kristin M. Engebretsen, PharmD, DABAT
Clinical Toxicologist, Regions Hospital
Clinical Associate Professor, University of Minnesota College of Pharmacy

Post Graduate Training:  Toxicology Residency:-Saint Paul Ramsey Medical Center, St. Paul, MN
Gradauate Education: PharmD, University of Minnesota College of Pharmacy, Minneapolis, MN
Undergraduate Education: BS Chemistry, St. Norbert College, DePere, WI
 
 

 
Peer Reviewed Articles:

Alberto, F., Lee, J., Brutlag, A., Hovda, L. and Engebretsen, K.M.  The use of intravenous lipid emulsions as an antidote in toxicology: a review. Journal of Veterinary Emergency Critical Care, 2010 (article in press).

Engebretsen, KM
 , Kazmazarek K, Morgan JL, Holger JS. High-dose insulin therapy in beta-blocker and calcium channel-blocker poisoning.  Clin Tox. 2011
April–May 2011, Vol. 49, No. 4 , Pages 277-283 (doi:10.3109/15563650.2011.582471)
 
Holger J, Engebretsen KM, Stellpflug SJ, Cole JB.  High dose insulin case series.  Clin Tox 2011.  (submitted 4/2011/in review)
 
Lam SW, Engebretsen KM, Bauer SR. Toxicology Today: what you need to know now. J Pharm Pract 2011 ; 24 (2); 174-188. 
 
Engebretsen KM, Morgan MW, Stellpflug SJ, Cole JB, Andersn CP, Holger JS.  Addition of phenylephrine to high-dose insulin in dihydropyridine overdose does not improve outcome.  Clin Toxicol (Phila) 2010 Oct;48(8):806-12.  erratum in Clin Toxicol (Phila) 2010 Nov; 48(9):965.

 

Stellpflug SJ; Fritzlar SJ, Cole JB, Engebretsen KM, Holger.   Cardiotoxic Overdose Treated with Intravenous Fat Emulsion and High-Dose Insulin in the Setting of Hypertrophic Cardiomyopathy. J Med Toxicol. 2010 Dec 21.

 

Engebretsen K, Sryring RS:  Beta Andrenergic Receptor Antagonists.  In: Blackwell’s Five-Minute Veterinary Consult (5MVC) Clinical Companions Small Animal Toxicology.  Wiley-BlackWel 2010

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Sryring RS, Engebretsen K: Calcium Channel  Receptor Antagonists.  In: Blackwell’s Five-Minute Veterinary Consult (5MVC) Clinical Companions Small Animal Toxicology.  Wiley-BlackWel 2010.

 

 

Stellpflug SJ, Harris CR, Engebretsen KM, Cole JB, Holger JS.  Intentional overdose with cardiac arrest treated with Intravenous fat emulsion and high dose insulin.  Brief Communication.  Clinical Toxicology  2010 Feb 8.  Early Online pp. 1-3.

 

Ablorh NA, Nitu F, Engebretsen K,  Thomas DD, Holger JS.  Insulin-dependent Rescue from Cardiogenic Shock is not Mediated by Phospholamban Phosphorylation.  Clin Toxicol 2009 April 47(4): 296-302.

Holger JS, Engebretsen KM, et al.  High dose insulin for toxin induced myocardial shock.  J Clin Toxicol  2009 April 47(4): 303-7.

Holger JS, Engebretsen KM, Fritzlar SJ, et al.  Insulin versus vasopressin and epinephrine to treat beta-blocker toxicity.  J Clin Tox, 2007 May; 45(4):396 - 401

 

Engebretsen KM, Harris CR, Wood J.  Cardiotoxicity and Late Onset Seizures with Citalopram Overdose.  J Emerg Med. 2003 Aug;25(2):163-6

 

Holger JS, Harris CR, Engebretsen KM.  Physostigmine, Sodium Bicarbonate, or Hypertonic Saline to Treat Diphenhydramine Toxicity.  Veterinary and Human Toxicology, 2002 Feb; 44(1) 1-4.

 

Engebretsen K: Morphine. In: Harris CR (ed): Emergency Management of Selected Drugs of Abuse. Dallas, TX: ACEP Publishing, October 2000, pp 67-75.

 

Engebretsen K: Methadone and LAAM. In: Harris CR (ed): Emergency Management of Selected Drugs of Abuse. Dallas, TX: ACEP Publishing, October 2000, pp 95-103.

 

Engebretsen KM, Harris CR. Caffeine and Related Nonprescription Sympathomimetics. In: Ford MD, Delaney KA, Ling LJ, Erickson T (eds). Clinical Toxicology. Philadelphia: W.B. Saunders, 2000.

 

Kingston RL, Chen WL, Borron SW, Sioris LJ, Harris CR, Engebretsen KM. Chlorpyrifos: A Ten-Year US Poison Center Exposure Experience. Veterinary and Human Toxicology, 1999; 41(2):87-92.



Abstracts:


Holger JS, Engebretsen KM, Stellpflug SJ, Cole JB, Harris CR. High dose insulin case series. Clin Toxicol 2010;48(6):613.  Abstract. Poster Presentation, North American College of Clinical Toxicology, October 7-12, 2010.

 

Stellpflug SJ, Fritzlar SJ, Cole JB, Engebretsen KM, Holger JS. Overdose of Diltiazem, Metoprolol, and Amiodarone Treated Successfully with Intravenous Fat Emulsion and High Dose Insulin in an Awake Patient. Clin Toxicol 2010;48(6):612.  Abstract. Poster Presentation, North American College of Clinical Toxicology, October 7-12, 2010

 

Engebretsen KM, Ortega H:  Lethal Lead Level in a Pediatric Patient Successfully Treated with Oral Succimer.  Oral Presentation Clin Tox Occ Med Subspecialty.  Presented at NACCT, San Antonio, TX, 2009.

 

Morgan M, Engebretsen KM, Holger JS,  Stellpflug SJ, et al.  Addition of a Vasopressor to High Dose Insulin in Dihydropyridine Overdose Does Not Improve Outcome. Clin Tox Prsrsentated at NACCT, San Antonio, TX 2009.

 

Engebretsen KM, Ortega H:  Lethal Lead Level in a Pediatric Patient Successfully Treated with Oral Succimer.  Clin Tox Presented at NACCT, San Antonio, TX, 2009.

 

Engebretsen KM, Holger JS, Harris CR.  Therapeutic Misadventures of High Dose Insulin without Adverse Effects.  Clin Tox Presented at NACCT, Toronto Canada, 2008

 

Engebretsen KM,  Holger JS:  Determining Mechanism of Intracellular Inotropy of High Dose Insulin in Toxin Induced Myocardial Depression.  (Abstract) Presented SAEM, Washington DC 2008.

 

Engebretsen KM, Marini JJ, Holger JS:  High Dose Insulin In Multiple Drug Overdose.  Clin Tox, 2007 (Abstract) Presented at NACCT, New Orleans October 2007

 

Holger JS, Engebretsen KM, Fritzlar SJ, Patten LC and Harris CR:  Insulin Versus Vasopressin and Epinephrine To Treat Beta-Blocker Toxicity.  Abstract and Platform Presentation.  Clin Tox, 2005: (in press) And research accepted and given for  Platform Presentation at the  North American Academy of Clinical Toxicolgy Meeting:  Orlando, Florida; September 2005.  

 

DeBoer LG, Engebretsen KM, Harris CR: Paroxysmal Sympathetic Storm (Diencephalic Seizures) Following Methadone Overdose. Clin Tox, 2001; 39(3):314. (abstract) Presented at the European Association of Poisons Centres and Clinical Toxicologists XXI International Congress, Barcelona, Spain. May, 2001

 

Engebretsen KM, Harris CR: Severe Hyponatremia with Resultant Noncardiogenic Pulmonary Edema and Cerebral Edema Secondary to Ecstasy Intoxication. Clin Tox, 2001; 39(3):290. (abstract) Presented at the European Association of Poisons Centres and Clinical Toxicologists XXI International Congress, Barcelona, Spain. May, 2001

 

Harris CR, Engebretsen KM. Disposition of Acetaminophen Overdose Patients by Emergency Physicians. Clin Tox 1998, 36(5): 442. Presented at NACCT, Orlando, FL

 

Holger J, Harris C, Engebretsen K.  Comparison of Physostigmine, Sodium Bicarbonate, and Hypertonic Saline in the Treatment of Experimental Diphenhydramine Toxicity (Abstract). Acad Emerg Med 1997; 4(5) 452. Presented at SAEM Annual Meeting, Washington DC.

 

Gualtieri J, Filandrinos D, Engebretsen K.   a-Chloralose Poisoning: An unexpected Hazard for the Street Drug User .  Clin Tox 1997. Presented at NACCT Annual Meeting, St. Louis, Missouri.

 

Filandrinos D, Gualtieri J, Engebretsen K.   Fluid Loss and Water Intoxication Leading to Hyponatremia and Status Epilepticus in Amoxicillin Overdose.  Clin Toxic 1997 Presented at NACCT Annual Meeting, St. Louis, Missouri.

 
 
Book Chapters: 

    Sioris K, Engebretsen KM. Respiratory Care, Principles & Practice 2nd Edition. Pharmacology
    chapter.     Jones  nd  Bartlett Publishers, Sudbury Massachusettes. Submitted October 2009.
 
    Engebretsen KM, Sring B. “Beta Antagonist Overdose in Blackwell’s Five-Minute Veterinary Consult (5MVC) Clinical Companions. Wiley-    Blackwell. Submitted October 2009. 

    Syring B, Engebretsen KM. “Calcium Channel Antagonist Overdose in Blackwell’s Five-Minute Veterinary Consult
    (5MVC) Clinical  Companions. Wiley-Blackwell. Submitted October 2009.



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