Last updated: 2024/05/29
NAME: Sung-Chou Li (李松洲)
PERSONAL DATA:
Date and Place of Birth: 1976; Hsilo, Yunlin, Taiwan
Citizenship: Taiwan
Marital Status: Married
CONTACT INFORMATION:
Department of Medical Education and Research, No. 386, Dazhong 1st Rd. Zuoying Dist. Kaohsiung 813414 Taiwan
TEL: 886-7-342-2121 ext. 71510
E-Mail:
raymond.pinus@vghks.gov.tw
Personal page: https://sites.google.com/site/raymondpinus/
EDUCATION:
PhD in Bioinformatics, March 2011, Taiwan International Graduate Program in Bioinformatics (TIGP) co-organized by Academia Sinica and National Yang-Ming University, Taipei, Taiwan. Advisor: Dr. Wen-chang Lin.
M.S. in Biotechnology in Medicine, June 2005, National Yang-Ming University, Taipei, Taiwan. Advisor: Dr. Wen-chang Lin.
B.S. in Botany, June 2003, National Taiwan University, Taipei, Taiwan.
RESEARCH EXPERIENCES:
2018 August ~ present, Associate Research Fellow, Genomics and Proteomics Core lab., Department of Medical Research, Kaohsiung Chang Gung Memorial Hospital
2015 April ~ present, Director of Genomics and Proteomics Core lab., Department of Medical Research, Kaohsiung Chang Gung Memorial Hospital
2014 April ~ 2018 July, Assistant Research Fellow, Genomics and Proteomics Core lab., Department of Medical Research, Kaohsiung Chang Gung Memorial Hospital
2013 April ~ 2014 March, Research Associate, Genomics and Proteomics Core lab., Department of Medical Research, Kaohsiung Chang Gung Memorial Hospital
2011 March ~ 2013 March, Post-doctoral fellow in Genomics Research Center, Academia Sinica. Advisor: Dr. Wen-Hsiung Li
2005 September ~ 2006 August, Research assistant in Institute of BioMedical Science, Academia Sinica. Advisor: Dr.Wen-chang Lin.
INVITATIONAL PRESENTATIONS:
The 10th Asia Pacific Bioinformatics Conference (APBC2012). Melbourne, Australia, Jan. 17-19 2012, “miRNA arm selection and isomiR distribution in gastric cancer”
The training course of the Life Science Library, Academia Sinica. Taipei, Taiwan. Aug. 31, 2011. “Introduction to the miRNA-related databases and the application of NGS tech. in miRNA studies”
Invited presentation in Kaohsiung Veterans General Hospital. Kuohsiung, Taiwan. Aug. 24, 2011. “The applications of NGS technology in biomedical studies”
The 9th Asia Pacific Bioinformatics Conference (APBC2011). Inchon, Korea. Jan 11‐14 2011, “UMARS: Un-MAppable Reads Solution”
The 9th International Conference on Bioinformatics (InCoB2010). Tokyo, Japan. Sep. 26-28, 2010. “Discovery and characterization of medaka miRNA genes by next generation sequencing platform”
The training course of the Life Science Library, Academia Sinica. Taipei, Taiwan. Aug. 24, 2010. “The applications of NGS technology and the on-line resources providing these application services”
The training course of the Life Science Library, Academia Sinica. Taipei, Taiwan. May 12, 2010. “Introducing miRBase and other databases related to miRNA”
SCHOLARSHIPS AND AWARDS:
2016 生策會 第十三屆 國家新創獎－臨床新創獎
2016 Travel grant of Asian Society for Pediatric Research 2016 (ASPR2016) meeting
2011中央研究院院聘博士後研究人員 (2011 July ~ 2013 June)
2011 傑出人才基金會優秀學生出國開會補助
2011 國科會國內研究生出席國際學術會議補助
2011 TIGP STUDENT CONFERENCE TRAVEL GRANT
2008第14屆細胞及分子生物新知研討會 徐千田基金會 優秀論文獎 佳作
SERVICES:
Journal reviewer:
2020: Biomarkers, Cardiovascular Therapeutics, Medical Science Monitor, Oxidative Medicine and Cellular Longevity
2019: Epigenomics, International Journal of Molecular medicine, Frontiers in Oncology, European Journal of Pharmacology, Molecular Genetics and Genomic Medicine, Current Medicinal Chemistry, Archives of Medical Research, Molecular Medicine Reports, Immunological Investigation
2018: Gene, Journal of Biomedical Science, Journal of Applied Biomedicine, Virus Research, BioMed Research International, Pathology-Research and Practice
2017: Journal of Drug Targeting, Pathology-Research and Practice, Gene, eBioscience, Plos One, Virus Research
2016: British Biotechnology Journal
2015: Annual Research and Review in Biology
2014: BMC Genomics, Computational Biology and Chemistry
2013: Journal of Biomedical Science
2012: Virology Journal
2011: Marine Genomics
2010: Bioinformatics, BMC Bioinformatics
2019: FEBS
2018: BMC Genomics
Journal Guest Editor:
2019~2020: Frontiers in Genetics
Research professional specialty:
Bioinformatics
MiRNA biology
Next-generation sequencing (NGS)
Genomics
Disease biomarker
PUBLICATION LIST:
Journal paper (Selected first- or corresponding-author publications from a total of 96)
Complete list of publications: https://goo.gl/mKGOYh
#JCR 2016
No.
Article
42
Yu HR, Huang HC, Chen IL, Li SC: Exosomes Secreted by Wharton's Jelly-Derived Mesenchymal Stem Cells Promote the Ability of Cell Proliferation and Migration for Keratinocyte. Int J Mol Sci 2024, 25(9).
41
Wang LJ, Li SC, Chou WJ, Kuo HC, Lee SY, Lin WC: Human transcriptome array analysis and diffusion tensor imaging in attention-deficit/hyperactivity disorder. J Psychiatr Res 2024, 172:229-235.
40
Lin SH, Hsu CY, Li SC: Increased Circulating CD14+ Monocytes in Patients with Psoriatic Arthritis Presenting Impaired Apoptosis Activity. Biomedicines 2024, 12(4).
39
Wang LJ, Li SC, Yeh YM, Lee SY, Kuo HC, Yang CY: Gut mycobiome dysbiosis and its impact on intestinal permeability in attention-deficit/hyperactivity disorder. J Child Psychol Psychiatry 2023, 64(9):1280-1291.
38
Lin CH, Li SC, Lin MH, Ho CJ, Lu YT, Lin Y, Lin PH, Tsai KW, Tsai MH: S100A6 participates in initiation of autoimmune encephalitis and is under epigenetic control. Brain Behav 2023, 13(3):e2897.
37
Hsu TY, Cheng HH, Lan KC, Hung HN, Lai YJ, Tsai CC, Fan WL, Li SC: The abundances of LTF and SOD2 in amniotic fluid are potential biomarkers of gestational age and preterm birth. Sci Rep 2023, 13(1):4903.
36
Weng KP, Chien KJ, Huang SH, Huang LH, Lin PH, Lin Y, Chang WH, Chen CY, Li SC: iTRAQ Proteomics Identified the Potential Biomarkers of Coronary Artery Lesion in Kawasaki Disease and In Vitro Studies Demonstrated That S100A4 Treatment Made HCAECs More Susceptible to Neutrophil Infiltration. Int J Mol Sci 2022, 23(21).
35
Li SC, Lan KC, Hung HN, Huang WT, Lai YJ, Cheng HH, Tsai CC, Huang KL, You HL, Hsu TY: HSPA4 Is a Biomarker of Placenta Accreta and Enhances the Angiogenesis Ability of Vessel Endothelial Cells. Int J Mol Sci 2022, 23(10).
34
Wang LJ, Kuo HC, Lee SY, Huang LH, Lin Y, Lin PH, Li SC: MicroRNAs serve as prediction and treatment-response biomarkers of attention-deficit/hyperactivity disorder and promote the differentiation of neuronal cells by repressing the apoptosis pathway. Transl Psychiatry 2022, 12(1):67.
33
Wang LJ, Li SC, Li SW, Kuo HC, Lee SY, Huang LH, Chin CY, Yang CY: Gut microbiota and plasma cytokine levels in patients with attention-deficit/hyperactivity disorder. Transl Psychiatry 2022, 12(1):76.
32
Wang LJ, Huang YC, Lin PY, Lee Y, Hung CF, Hsu ST, Huang LH, Li SC: BST-1 as a serum protein biomarker involved in neutrophil infiltration in schizophrenia. World J Biol Psychiatry 2021:1-11.
31
Yu HR, Hsu TY, Tsai CC, Huang HC, Cheng HH, Lai YJ, Lin YJ, Chen CC, Li SC, Yang K: The Functional DNA Methylation Signatures Relevant to Altered Immune Response of Neonatal T Cells with l-Arginine Supplementation. Nutrients 2021, 13(8).
30
Li SC, Kuo HC, Huang LH, Chou WJ, Lee SY, Chan WC, Wang LJ: DNA Methylation in LIME1 and SPTBN2 Genes Is Associated with Attention Deficit in Children. Children (Basel) 2021 Jan 29;8(2):92.
29
Li SC, Tsai KW, Huang LH, Weng KP, Chien KJ, Lin Y, Tu CY, Lin PH: Serum proteins may facilitate the identification of Kawasaki disease and promote in vitro neutrophil infiltration. Sci Rep 2020, 10(1):15645.
28
Hsu TY, Tsai KW, Lan KC, Hung HN, Lai YJ, Cheng HH, Tsai CC, Li SC: Identifying the potential protein biomarkers of preterm birth in amniotic fluid. Taiwan J Obstet Gynecol 2020, 59(3):366-371.
27
Tsai MH, Lin CH, Tsai KW, Lin MH, Ho CJ, Lu YT, Weng KP, Lin Y, Lin PH, Li SC: S100A6 Promotes B Lymphocyte Penetration Through the Blood–Brain Barrier in Autoimmune Encephalitis. Front Genet. 2019 Nov 22;10:1188. doi: 10.3389/fgene.2019.01188. eCollection 2019.
26
Kuo HC, Pan CT, Huang YH, Huang FC, Lin YS, Li SC, Huang LH: Global Investigation of Immune Repertoire Suggests Kawasaki Disease Has Infectious Cause. Circ J. 2019 Sep 25;83(10):2070-2078. doi: 10.1253/circj.CJ-19-0206
25
Li SC, Huang LH, Chien KJ, Pan CY, Lin PH, Lin Y, Weng KP, Tsai KW: MiR-182-5p enhances in vitro neutrophil infiltration in Kawasaki disease. Mol Genet Genomic Med 2019:e990.
24
Wang LJ, Yang CY, Chou WJ, Lee MJ, Chou MC, Kuo HC, Yeh YM, Lee SY, Huang LH, Li SC: Gut microbiota and dietary patterns in children with attention-deficit/hyperactivity disorder. Eur Child Adolesc Psychiatry 2019 May 22. doi: 10.1007/s00787-019-01352-2
23
Yang CM, Chang HS, Chen HC, You JJ, Liou HH, Ger LP, Li SC, Tsai KW: Low C6orf141 Expression Is Significantly Associated With a Poor Prognosis in Patients With Oral Cancer. Sci Rep 2019, 9(1):4520.
22
Huang LH, Kuo HC, Pan CT, Lin YS, Huang YH, Li SC: Multiomics analyses identified epigenetic modulation of the S100A gene family in Kawasaki disease and their significant involvement in neutrophil transendothelial migration. Clin Epigenetics 2018, 10(1):135.
21
Yu HR, Huang LH, Li SC. Roles of microRNA in the immature immune system of neonates. Cancer Lett. 2018 Oct 1;433:99-106
20
Wang LJ, Li SC, Lee MJ, Chou MC, Chou WJ, Lee SY, Hsu CW, Huang LH, Kuo HC.: Blood-Bourne MicroRNA Biomarker Evaluation in Attention-Deficit/Hyperactivity Disorder of Han Chinese Individuals: An Exploratory Study. Front Psychiatry. 2018 May 29;9:227.
19
Huang LH, Lin PH, Tsai KW, Wang LJ, Huang YH, Kuo HC, Li SC: The effects of storage temperature and duration of blood samples on DNA and RNA qualities. PLoS One 2017, 12(9):e0184692.
18
Li SC, Wang FS, Yang YL, Tiao MM, Chuang JH, Huang YH:
Microarray Study of Pathway Analysis Expression Profile Associated with MicroRNA-29a with Regard to Murine Cholestatic Liver Injuries. Int J Mol Sci 2016, 17(3).
17
Li SC, Chan WC, Huang YH, Guo MM, Yu HR, Huang FC, Kuo HC: Major methylation alterations on the CpG markers of inflammatory immune associated genes after IVIG treatment in Kawasaki disease. BMC Med Genomics 2016, 9 Suppl 1:37.
16
Kuo HC, Li SC, Guo MM, Huang YH, Yu HR, Huang FC, Jiao F, Andrade J, Chan WC: Genome-Wide Association Study Identifies Novel Susceptibility Genes Associated with Coronary Artery Aneurysm Formation in Kawasaki Disease.
PLoS One 2016, 11(5):e0154943
15
Kuo HC, Hsieh KS, Ming-Huey Guo M, Weng KP, Ger LP, Chan WC, Li SC: Next-generation sequencing identifies micro-RNA-based biomarker panel for Kawasaki disease. J Allergy Clin Immunol 2016, 138(4):1227-1230.
14
Tsai KW, Chang B, Pan CT, Lin WC, Chen TW, Li SC: Evaluation and application of the strand-specific protocol for next-generation sequencing. Biomed Res Int 2015, 2015:182389.
13
Pan CT, Tsai KW, Hung TM, Lin WC, Pan CY, Yu HR, Li SC: miRSeq: A User-Friendly Standalone Toolkit for Sequencing Quality Evaluation and miRNA Profiling. Biomed Res Int 2014, 2014:462135.
12
Li SC, Tsai KW, Pan HW, Jeng YM, Ho MR, Li WH: MicroRNA 3' end nucleotide modification patterns and arm selection preference in liver tissues. BMC Syst Biol 2012, 6 Suppl 2:S14.
11
Li SC, Liao YL, Ho MR, Tsai KW, Lai CH, Lin WC: miRNA arm selection and isomiR distribution in gastric cancer. BMC Genomics 2012, 13 Suppl 1:S13.
10
Chang HT, Li SC, Ho MR, Pan HW, Ger LP, Hu LY, Yu SY, Li WH, Tsai KW: Comprehensive analysis of microRNAs in breast cancer. BMC Genomics 2012, 13 Suppl 7:S18.
9
Li SC, Liao YL, Chan WC, Ho MR, Tsai KW, Hu LY, Lai CH, Hsu CN, Lin WC: Interrogation of rabbit miRNAs and their isomiRs. Genomics 2011, 98(6):453-459.
8
Li SC, Chan WC, Lai CH, Tsai KW, Hsu CN, Jou YS, Chen HC, Chen CH, Lin WC: UMARS: Un-MAppable Reads Solution. BMC Bioinformatics 2011, 12 Suppl 1:S9.
7
Li SC, Chan WC, Hu LY, Lai CH, Hsu CN, Lin WC: Identification of homologous microRNAs in 56 animal genomes. Genomics 2010, 96(1):1-9.
6
Li SC, Chan WC, Ho MR, Tsai KW, Hu LY, Lai CH, Hsu CN, Hwang PP, Lin WC: Discovery and characterization of medaka miRNA genes by next generation sequencing platform. BMC Genomics 2010, 11 Suppl 4:S8.
5
Lin WC, Li SC, Shin JW, Hu SN, Yu XM, Huang TY, Chen SC, Chen HC, Chen SJ, Huang PJ et al: Identification of microRNA in the protist Trichomonas vaginalis. Genomics 2009, 93(5):487-493.
4
Yu X, Zhou Q, Li SC, Luo Q, Cai Y, Lin WC, Chen H, Yang Y, Hu S, Yu J: The silkworm (Bombyx mori) microRNAs and their expressions in multiple developmental stages. PLoS ONE 2008, 3(8):e2997.
3
Li SC, Shiau CK, Lin WC: Vir-Mir db: prediction of viral microRNA candidate hairpins. Nucleic Acids Res 2008, 36(Database issue):D184-189.
2
Li SC, Tang P, Lin WC: Intronic MicroRNA: Discovery and Biological Implications. DNA Cell Biol 2007, 26(4):195-207.
1
Li SC, Pan CY, Lin WC: Bioinformatic discovery of microRNA precursors from human ESTs and introns. BMC Genomics 2006, 7:164.