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Rare Sugar Symposium 2014 in Kagawa

Organized by Faculty of Agriculture, Kagawa University, the symposium will be held on 29-30 March at Kagawa International Conference Hall, Takamatsu. Invited speaker from Finland, England, Belgium, Thailand, Korea and China are gathering to reveal their up to date research on various aspect of rare sugars. Register online at: http://isrs.kagawa-u.ac.jp Registration deadline: March 15, 2014. Contact e-mail: rare2014@ag.kagawa-u.ac.jp URL: http://isrs.kagawa-u.ac.jp

CJ CheilJedang produced xylose in Philippine plant
The sweetness of D-xylose is 63% of sucrose. It inhibit sucrase which will help reduce cane sugar assimilation.  CJ CheilJedang Corp. in South Korea's food firm had dedicated a joint-venture plant in the Philippines to produces xylose, a natural sweetener derived from coconut shells.  CJ Toyota Tsusho Philippines Inc.'s plant, built in Davao del Sur in Mindanao, has an annual capacity of 15,000 tons of xylose.
The company also plan to produce Tagatose. The launch date will be on 15 Dec 2012. Tagatose is obtain from milk's lactose. After hydrolysis to obtain galactose and glucose, galactose then isomeise by L-arabinose isomerase to obtain tagatose.  Tagatose market is for reduce blood glucose after meal.
 
Izumoring, a strategy for production of rare sugars by biocatalyst
Chemical synthesis of monosaccharides isomer can be done by using single or multiple organic chemical reaction. All these reactions were established and could be found in elementary organic chemistry textbook. Most of the work were developed by Emil Fisher and many other scientist. Recently, another approach for produce monosaccharides isomer by biocatalyst was developed. These approach use single or multiple enzymes combined with microbial reaction to transform the more abundant sugars like glucose, fructose or mannose to rare sugar like D-psicose, D-allose  etc. The key enzyme for this method was D-tagatose-3-epimerase and the strategy was called Izumoring. Theretically the strategy can produce all isomer of D and L form of monosaccharide. Example of rare sugars produced by this method are D-psicose, L-psicose, D-tagatose, D-altrose, D-allose, allitol, L-ribose, L-fructose. Rare sugar research station in Kagawa University, Japan is producing  kilogram level of these rare sugars for research and application.
 
MIT scientist synthesis rare sugars by inorganic catalyst.
Massachuset Instittue of Technology (MIT) scientist anounce  new inorganic catalyst for rare sugars production.  Leading by a team of Professor Yuriy Román, the new catalyst was Sn-Beta zeolite in the presence of sodium tetraborate. It shown to catalyze the selective epimerization of aldoses in aqueous media. The reaction proceeds by way of a rather unusual 1,2 carbon-shift mechanism, wherein C-C bonds move within the molecule’s backbone. The result published on October 2012 in Nature Communications. The research group will then investigate in more detail the unusual carbon-shift mechanism of this reaction.
 
 
FDA accept D-psicose as safe for food use.

The Food and Drugs Administration of USA (FDA) recently anounce D-psicose as generally recognized as safe (GRAS) for food use on August 18, 2011. Following several safety report for food use done in Kagawa and from other sources, the FDA anounce D-psicose safety following request from Cheiljedang Inc. from Korea follow Letter GRAS Notice No. GRN 000400.

 
Japanese company produce D-psicose for food use.
Rare sugar became more and more acceptable in Japan society. Recent report showed rare sugars are benefits in many aspect to human health. Company like Misutani and Fushimi are joining with Rare Sugar Research Center of Kagawa University to transfer Izumoring technology for industrial production of rare sugar especially D-psicose for food use. D-psicose was incoporated in bakery, candy, ice cream and other foods now available in Japan market.
 
Xylitol production expanded.
Xylitol is very popular and can be found in chewing gum, tooth paste and candy. The estimated world xylitol production in 2011 are around 60,000 tons. China is the major xylitol producer follow by Finland, Russia, the United States, Italy and Japan. Xylitol is hepatotoxic to dog at large dose of 0.5 g/kg. A 50,000 ton per year xylitol production plant was projected in Changchun city, China.
 
The 6th International Symposium of ISRS (Rare Sugar Congress 2014 in Kagawa) will be held in Kagawa.
ISRS committee anounce rough schedule of next rare sugar symposium on Autumn of 2014. The Venue will be in Kagawa. More detail will be anounce in this website.
 
The renewal Rare Sugar Research Station official opened.
In the afternoon of May 25, 2012, about 60 citizen in Kagawa area and local TV station come to Kagawa University, Miki Cho, to join the openning ceremony of the renewal Rare Sugar Research Station. The ceremony was arranged at university auditorium. Mr. Tsutsui, Mayor of Miki-cho, Prof. Itano and Prof. Ohira, Trustees of Kagawa University and Prof. Mori, Dean of Faculty of Medicine were invited by Prof. Tokuda president of rare sugar recearch center, to officially open the center. The station was open for all visitor to visit D-psicose production.