Mosquito immunity and interaction with pathogens



Zou, Z., Souza-Neto, J. A., Xi, Z., Kokoza, V., Shin, S.W., Dimopoulos, G. and Raikhel, A.S. 2011. Transcriptome analysis of Aedes aegypti transgenic mosquitoes with altered immunity. Plos Pathog. 7, 11. e1002394 PMID: 22114564.


Zou, Z., Shin, S.W., Alvarez, K.S., Kokoza, K. and Raikhel, A.S. 2010. Distinct melanization mechanisms in the mosquito Aedes aegypti. Immunity 32:41-53. PMID: 20152169

Zou, Z., Shin, S.W., Alvarez, K.S., Bian, G., Kokoza, K., and Raikhel, A.S. 2008 Mosquito RUNX4 in the immune regulation of PPO gene expression and its effect on avian malaria parasite infection. Proc. Natl. Acad. Sci. USA 105: 18454-18459. PMID: 19011100

Shin SW, Bian G, Raikhel AS. 2006. A toll receptor and a cytokine, Toll5A and Spz1C, are involved in toll antifungal immune signaling in the mosquito Aedes aegypti. J Biol Chem. 281: 39388-39395. PMID: 17068331

Cheon, H.-M., Shin, S.W., Bian, G., Park, J.H. and Raikhel, A.S. 2006. Regulation of lipid metabolism genes, lipid carrier protein lipophorin and its receptor, during immune challenge in the mosquito Aedes aegypti. J. Biol. Chem. 281, 8426-8435. PMID: 16449228  

Shin, S. W., Kokoza, V., Bian, G., Cheon, H. M., Kim, Y. J. and Raikhel, A. S. 2005. REL1, a homologue of Dorsal regulates toll antifungal immune pathway in the female mosquito, Aedes aegypti. J. Biol. Chem. 280: 16499-16507. PMID: 15722339

Bian, G., Shin, S.W., Cheon, H. M., Kokoza, V. and Raikhel, A. S. 2005. Transgenic alteration of Toll immune pathway in the female mosquito Aedes aegypti. Proc. Natl. Acad. USA 102, 13568-13573. PMID: 16157887

Shin, S. W., Kokoza, V., Lobkov, Y., and Raikhel, A.S. 2003. Relish-mediated immunodeficiency in the transgenic mosquito, Aedes aegypti. Proc. Natl. Acad. USA, 100: 2616-2632. PMID: 12594340

Shin, S. W., Kokoza, V., Ahmed, A., and Raikhel, A.S. 2002. Characterization of three alternatively spliced isoforms of the Rel/NF-κB transcription factor Relish from the mosquito Aedes aegypti. Proc. Natl. Acad. USA 99: 9978-9983. PMID: 12119421











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