About

Introduction

RADBIOMOD is a simple and user-friendly software tool for the biological evaluation of radiotherapy treatment plans. Multiple radiobiological models are available including:

• The Zaider and Minnerbo birth-death stochastic tumour control probability (TCP) model

• The Poisson TCP model

• The Gay and Niemierko equivalent uniform dose (EUD)-based TCP and normal tissue complication probability (NTCP) models

• The Lyman-Kutcher-Burman (LKB) NTCP model

Multiple graphing options are available including:

• Differential and cumulative dose-volume histogram (DVH) graphing

• TCP and NTCP graphing

Requirements

Microsoft Excel 2003 or newer with macros enabled, running on Microsoft Windows (Mac OS X not supported).

Citation

Chang JH, Gehrke C, Prabhakar R, Gill S, Wada M, Lim Joon D, Khoo V. RADBIOMOD: A simple program for utilising biological modelling in radiotherapy plan evaluation. Phys Med. 2016 Jan;32(1):248-54.

Disclaimer

1. To the extent permitted by law:

a. Joe H. Chang and Christopher J. Gehrke (the Authors) give no warranty of any type, either express or implied, for RADBIOMOD (the Program), and any other material supplied with the Program; and

b. The entire risk of loss, damage or unsatisfactory performance of the Program (no matter how arising, including as a result of negligence on behalf of the Authors) rests with the user (the User). In no event will the Authors be liable for damages, including any general, special, incidental or consequential damages, arising out of the installation of the Program, any attempt to install the Program, the use of the Program, the inability to use the Program, the use of data embodied in, or obtained from, the Program or the use of any documentation or other material accompanying the Program.

2. The numerical data and formulas contained in the Program are provided solely for the purpose of illustrating the modelling framework for projecting possible outcomes under different scenarios. The Authors give no warranty and make no representation as to the accuracy, reliability, timeliness or other features of any data contained in the Program or data obtained from using the Program. In particular:

a. The User should rely on the User's own inquiries as to the accuracy and relevance of the data incorporated into or applicable to the Program;

b. The User should not use the Program as the basis for making any decision or embarking on any course of action; and

c. The data contained in the Program and the output of the Program should not be regarded as representative of any current data or forecasts of what will happen under a given set of conditions.

3. The Program is based on input (parameters and projections) from data obtained by the Authors which may be updated from time to time and be relevant to the Program. Users should rely on their own inquiries in relation to the accuracy and relevance of any available data and its appropriateness for updating the Program. The Authors have provided some guidance as to the manner of inputting updated data into the Program however the Authors accept no responsibility for errors in the input data, the lack of currency of the input data, any problems experienced by the user in updating or attempting to update the input data, or the results obtained from running the Program using the updated data.

4. If you have obtained this Program otherwise than from the Authors, the Program may have been modified by a previous user. The Authors accept no liability in relation to modifications made by any user.

5. The intellectual property in this Program is and remains the property of the Authors.

6. The Program is made available to Users for their own use and may be provided or re-disseminated by them to another party. The User who re-disseminates the Program should include the disclaimer and conditions of use in its current form with the Program, and identify any modifications made by the User to the Program and documentation.

7. The User may modify the Program. However, the Authors would appreciate being informed of any modifications made by the User and being offered the opportunity to add any extra data and modifications to its own version of the Program. When making modifications of the Program available to the Authors, please also identify who created the material contained in the modifications.

8. Users who have obtained the Program from a person other than the Authors are still bound by these conditions of use. The Authors recommend that Users contact the Authors for the original version of the Program.