In order to improve safety of mechanical ventilation a selection of preclinical and clinical investigators initiated the PROtective VEntilation Network (PROVENet) to perform multicenter clinical studies, randomized controlled trials, and meta-analyses. PROVENet was established following several smaller single–center and multicenter investigations into potential protective effects of certain mechanical ventilation settings and/or – strategies in critically ill patients and surgical patients.

Mission of PROVENet

The mission of the PROVE Network are to test novel mechanical ventilation strategies and – devices, as well as non–ventilatory supplemental strategies and –devices to improve the care and safety of patients who need mechanical ventilation, including those in emergency units, intensive care units and operating rooms.

PROLUNG - a successor of PROVENet