This site exists to provide information to sufferers of a severe type of pregnancy sickness called Hyperemesis Gravidarum (HG).

For information about available treatments in the UK see Treatments
If your GP doesn't know about treatment or refuses to prescribe medication see Obtaining Treatment
For links to treatment protocols see Documents and abstracts from recent research in Research.
Fed up of people telling you to try ginger or saying it's only morning sickness? See What to say when... 
Don't believe the hype. There are numerous supposed miracle cures for 'morning sickness', see what we think at 'Miracle Cures'

If you are isolated and need a friendly ear, Pregnancy Sickness Support (PSShave a national network of former sufferers. You can request or offer support through the link (UK Sufferers Support Network). For other links and support forums see Support and Links.

If you have any tips, comments or suggestions let us know using the Your Comments page.


Two recent discoveries published in 2017 and 2018 have led to a breakthrough in understanding what causes HG.  Receptors for a protein called GDF15 have been discovered to be in the part of the brain that induces the sensation of nausea. Independently of this discovery, the gene which codes for GDF15 has been found to be highly associated with having severe pregnancy sickness. Read more about this here here

The second International Colloquim on Hyperemesis Gravidarum will take place in Windsor in October 2017. For details see HG Conference

Jun 2016. The Royal College of Obstetricians and Gynaecologists have published new Green Top Guidelines (GTG) for the management of Nausea and Vomiting of Pregnancy and Hyperemesis Gravidarum. The GTGs have taken four years to produce and three trustees of Pregnancy Sickness Support have been involved as co-authors from the beginning. The guidelines are freely available online RCOG GTG.