Analytical Mass Spectrometry (質譜分析)

Scope:

The course is directed to graduate students who specialize or are interested in analytical, pharmaceutical, or clinical chemistry, as well as biochemistry, biotechnology, systems biology, and related areas.

It will provide a comprehensive overview of mass spectrometry technology, methodology, and applications.

 

Contents (by topic):


1. Introduction


2. Vacuum system

 

3. Sample interface and ion source

 

4. Mass analyzer

 

5. Ion detector

 

6. * Mid-term exam

 

7. Identification of molecules

 

8. Quantitative analysis

 

9. Hyphenation with other separation techniques

 

10. Mass spectrometry imaging

 

11. * Students’ presentations

 

12. Selected applications

 

13. * Final exam

 

Evaluation:

* Final mark will be based on the results of the mid-term exam (30%), presentation (30%), and the result of the final exam (40%). Additional points (up to 15%) can be gained for active participation in the class.

 

Requirements:

Students who have completed the Analytical Chemistry course are encouraged to participate.

 

Study material:

Handouts will be provided for selected topics.

Textbooks:

1) Urban P.L., Chen Y.-C., Wang Y.-S. 2016, Time-Resolved Mass Spectrometry: From Concept to Applications. Wiley, Chichester.

2) de Hoffmann E., Stroobant V. 2007, Mass Spectrometry: Principles and Applications, 3rd Edition. Wiley, Chichester.


Office hour:

Time: Friday, 14:00-15:00.

Place: student office of Prof. Urban's laboratory


Useful links: (This section will be expanded.)

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