標  I_n_n_o_v_a_t_i_o_n is our goal
Soxhlet extraction is one of the most prominent sample preparation techniques in chemical analysis. Our team developed on-line chromatographic and mass spectrometric strategies for the monitoring of the extraction process. They can be used to evaluate molecular extractability of biological samples and foodstuffs. [read more]

Droplets in oil are fused to initiate a reaction
Microliter droplets merge spontaneously due to hydrostatic forces, and a reaction is initiated.!divAbstract
Fusion of water-in-oil droplets enables facile and cost-effective optical assays using low-microliter volumes of samples and reagents. [read more]
Students from our lab demonstrated the possibility to adjust the level of ATP in a biocatalytic reaction using a feedback control system facilitated by a microcontroller module and program in C++. [read more]
Internet-of-Things (IoT) enters chemistry labs... What's next? Our team has developed first fully automated liquid-liquid extraction system coupled with mass spectrometry.
Automated extraction
This automated analytical system communicates with the internet and mobile phone network, interacting with the user by voice and screen. It enables monitoring dynamic processes such as dissolution of pharmaceutical formulations. [read more]
Our group members have developed a simple robotic system capable of analyzing samples by mass spectrometry. The device identifies the analyst (by fingerprint) and the sample (by barcode), collects the sample from a drop-off area, performs simple processing (addition of a reagent), injects the sample to mass spectrometer, collects the spectra, and disposes off the sample. It communicates with the outside world by touch-screen and web interfaces. [read more]
We have disclosed a simple method for profiling microbial aggregates in complex matrices such as probiotic drinks. It is based on sedimentation of bioparticles followed by capillary hydrodynamic separation. The separated cell aggregates are detected by an active pixel sensor, and imaged by on-line and off-line microscopy. [read more]

Micropatch-arrayed pads (MAPA) are introduced as a facile way to probe distributions of topical drugs on the surface of skin. [read more]!divAbstract
Computer screen and amateur digital camera were used to obtain spatiotemporal profiles of non-linear chemical processes at different wavelengths. [read moreSee also the highlight in Chemistry World magazine.!divAbstract
Our undergraduate project student co-invented a spectrotomography device that enables multi-dimensional profiling of non-homogeneous samples at different wavelengths. It distinguishes "islands" of (bio)molecules and live specimens in the three-dimensional space, and tracks their dynamics. [read more]!divAbstract
3D-printer and open-source electronics were used to construct a simple user-friendly interface for coupling open digital microfluidic chips with mass spectrometer. The platform has been applied to initiation and monitoring of glutathione oxidation in microliter-scale droplets. [read more]