All the read API calls support JSONP. If you want to see an in-depth look at JSONP see wikipedia. In short, if you pass a query parameter called callback and the picplz API will return JSON wrapped in a function call. That function will be whatever callback is set to. For example, if we call the interesting feed with the extra parameter the following should happen.

curl -H 'X-Pretty-JSON: 1' 'http://api.picplz.com/api/v2/feed.json?type=interesting&callback=my_callback'

    "result": "ok", 
    "value": {
        "more_pics": true, 
        "last_pic_id": 153217, 
        "pic_count": 200, 
        "pics": [

With JSONP you can request data cross-domain.