Cedars-Sinai Medical Center, CA, USA | 2019-present
Postdoctoral Scientist in Biomedical Sciences
Mentor: Prof. Simon Gayther
University of Illinois at Urbana-Champaign, IL, USA | 2013-2018
Ph.D. candidate in Computer Science
Thesis title: "Quantifying the Functional and Evolutionary Relationships among Sequences, Transcription Factor Binding and Gene Expression."
Advisor: Prof. Saurabh Sinha
National Taiwan University, Taipei, Taiwan
M.S. in Computer Science and Information Engineering | 2011-2013
Thesis title: “Gene Regulatory Network Inference and Complex Phenotype Prediction from Genetical Genomics Data”
Advisor: Prof. Kun-Mao Chao
B.S. in Computer Science and Information Engineering | 2007-2011
[J6] M. R. Jones*, P.-C. Peng*, S. G. Coetzee, J. Tyrer, A. L. Reyes, R. I. Corona, B. Davis, S. Chen, F. Dezem, J.-H. Seo, Ovarian Cancer Association Consortium, B. P. Berman, M. Freedman, J. T. Plummer, K. Lawrenson, P. Pharoah, D. J. Hazelett, S. A. Gayther. Ovarian Cancer Risk Variants are Enriched in Histotype-Specific Enhancers that Disrupt Transcription Factor Binding Sites. bioRxiv (2020): 10.1101/2020.02.21.960468.
[J5] P.-C. Peng, P. Khoueiry, C. Girardot, J. P. Reddington, D. A. Garfield, E. E. M. Furlong, S. Sinha, The Role of Chromatin Accessibility in cis-Regulatory Evolution. Genome biology and evolution 11.7 (2019): 1813-1828.
[J4] P. Khoueiry, C. Girardot, L. Ciglar, P.-C. Peng, H. E. Gustafson, S. Sinha, E. E. M. Furlong, Uncoupling Evolutionary Changes in DNA Sequence, Transcription Factor Occupancy and Enhancer Activity. eLife, 2017, 6:e28440
[J3] P.-C. Peng and S. Sinha, Quantitative Modeling of Gene Expression Using DNA Shape Features of Binding Sites. Nucleic Acids Research, 2016, 44(13): e120
[J2] P.-C. Peng, M.A.H. Samee, S. Sinha, Incorporating Chromatin Accessibility Data into Sequence-to-Expression Modeling. Biophysical Journal, 2015, 108(5):1257-1267
[J1] H.-C. Liu, P.-C. Peng, T.-C. Hsieh, T.-C. Yeh, C.-J. Lin, C.-Y. Chen, J.-Y. Hou, L.-Y. Shih, and D.-C. Liang, Comparison of Feature Selection Methods for Cross-Laboratory Microarray Analysis. IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2013, 10(3):593-604
[C6] Partitioned heritability and functional enrichment reveal ovarian cancer risk variants in histotype-specific enhancers that disrupt transcription factor binding sites. (poster) ASHG, Houston, USA, 2019. *This presentation was selected as a Reviewer’s Choice.
[C5] Quantifying the relationships among evolutionary changes in sequence, accessibility, TF binding and regulatory activity of enhancers of a well characterized developmental system. (talk) CSHL conference on Systems Biology: Global Regulation of Gene Expression, Cold Spring Harbor, USA, 2017
[C4] Quantitative modeling of gene expression by using DNA shape and accessibility data. (poster) Grace Hopper Celebration of Women in Computing, Houston, USA, 2016
[C3] Quantitative modeling of gene expression from sequence, using DNA shape-based model of binding sites. (poster) CRA-W Grad Cohort 2016, San Diego, USA, 2016
[C2] Quantitative modeling of gene expression from sequence, using DNA shape-based model of binding sites. (talk & poster) RECOMB/ISCB RSG, Philadelphia, USA, 2015
[C1] The role of chromatin accessibility in thermodynamics-based model of transcriptional regulation by enhancers. (poster) ISMB Regulatory Genomics SIG, Boston, USA, 2014
Rising Stars in EECS | 2019
Accomplishing Career Transitions Program | ASCB, USA, 2019
HHMI International Student Research Fellowship Finalist | HHMI, USA 2016
Grace Hopper Celebration Scholarship | Anita Borg Institute, 2015 and 2016
Google Anita Borg Memorial Scholarship| Google Inc., 2012
Studying Abroad Scholarship| Ministry of Education, Taiwan, 2012
Germany Summer Institute Program Scholarship | DAAD, Germany, 2012
Irving T. Ho Memorial Scholarship | Irving T. Ho Memorial Foundation, 2012
Presidential Award | National Taiwan University, 2007
Travel Grants:
ASCB Annual Meeting |ASCB, 2019, 2020
CRA-W Early Career Mentoring Workshops | Computing Research Association, 2018
CRA-W Grad Cohort Workshop | Computing Research Association, 2016
Cedars-Sinai Medical Center, CA, USA
Guest lecturer, BMS 510 Human Genetics and Genomics , Dennis Hazelett, Spring' 19
Mayo Clinic and UIUC Alliance, MN/FL and IL, USA
Leading Teaching Assistant, Computational Genomics Course, Summer'15, Summer'16, and Summer'17
University of Illinois at Urbana-Champaign, IL, USA
Teaching Assistant, CS 466 Introduction to Bioinformatics, Saurabh Sinha, Fall'16
National Taiwan University, Taipei, Taiwan
Teaching Assistant, CSIE 1212 Data Structure and Algorithm, Hsin-Mu Tsai, Spring'12
Teaching Assistant, CSIE 2136 Algorithm Design and Analysis, Hsin-Mu Tsai, Fall'11
Journal/Conference/Grant Referee | 2016 - present
Bioinformatics
2020 NSF Graduate Research Fellowship Program
2019 GHC Data Science track
2019 ABRCMS Computational and Systems Biology discipline
Service in Academic Committees
Graduate Academic Council, Department of Computer Science | UIUC, 2015-2018
Graduate Student Admission Committee, Department of Computer Science | UIUC, 2013-2015