T.vaginalis is the most common non-viral sexually transmitted infection affecting ~275 million people/yr worldwide and 3.7 million in the US. In 2014 the CDC identified trichomoniasis, the infection caused by T. vaginalis, as one of the Neglected Parasitic Infections (NPIs) in the United States.
About T.vaginalis Infection:
  • Infections are often asymptomatic but those that are symptomatic often result in vaginitis, urethritis, or prostatitis 
  • Infection increases risk of HIV transmission
  • Long-term infections lead to severe consequences such as increased risk of cervical cancer, prostate cancer, pre-term birth, and infertility
For more info, visit the CDC Trichomoniasis Fact Sheet
About the parasite:
  • T.vaginalis is a flagellated, extracellular protozoan parasite
  • Attachment and cytolysis are important in pathogenesis
  • Surface and secreted proteins are implicated in host-pathogen interactions