Overview - Welcome!

Welcome to the web page of Dr. Jin Ho Park's Laboratory and thank you for visiting! We are based out of the University of Massachusetts - Boston. To view our poster from the SfN conference, please see the attached file at the bottom of this page.

Dr. Park got his Ph. D. from the University of California, Berkeley. He did his postdoctoral work at the University of Virgina Charlottesville under Dr. Emilie Rissman before coming to the University of Massachusetts - Boston, in January of 2010.

Dr. Park’s research interests lie in investigating the neuroendocrinology of social behaviors, such as reproduction and aggression, and focuses on the molecular and genetic basis of reproductive behavior and environmental influences on reproduction and sexual differentiation.  Long-term persistence of male reproductive behavior after castration has been reported in numerous species, including humans; therefore, delineating the underpinnings of gonadal steroid-independent male sexual behavior will help understand the complex mechanisms that contribute to variability in sexual function. We utilize an animal model in which a large proportion of hybrid mice retain the full repertoire of male sexual behaviors 5-6 months after castration to investigate the molecular and genetic mechanisms underlying individual differences found in male reproductive behaviors. The long term goal is to utilize our findings to develop new treatments for sexual dysfunction that are independent of steroid hormones.

We study reproductive neuroscience using an integrative “systems” approach, allowing for a comprehensive examination of the environmental and neuroendocrine regulation of reproduction at multiple levels of analyses, from genetics to neuroanatomy to endocrinology to behavior. We employ a variety of techniques that encompass analyses at multiple levels such as immunocytochemistry, real time qPCR, protein quantification using western blots, timed hormonal infusions via indwelling catheters, hormone sampling and steroid hormone radioimmunoassay, ICV infusions with osmotic pumps, and familiarity with numerous behaviors including sex behavior, olfactory preference, aggression and stress.

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Nov 11, 2011, 3:28 PM