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O2 SM & ASVD : O2 Refs 151005 - 1407

Come back to:  638<742  


    1. W. Dock, Ann. Int. Med. 49: 699-705, 1958. "Research in Arteriosclerosis The-First 50 Years"

    2. N.N. Kipshidge, Bull. Exp. Biol. Med. 47: 447-53, 1959. "The Effect of Oxygen-Deficiency on the Development of Experimental Atherosclerosis of the Coronary Arteries"   * 

    3. K. Kjeldsen, J. Atherosclerosis Res. 10: 173-8, 1969. "Reversal of Rabbit Atheromtosis by Hyperoxia"  * 
 
    4. P. Astrup, Atherosclerosis: Proceedings of the Second International Symposium: 108-11;1970:--"The Effects of Exposure to Carbon Monoxide; Hypoxia and Hyperoxia on the Development of Experimental Atheromatosis in Rabbits"   * 

    5. S.A. Kumar, "Oxygen Uptake and Release by Red Cells
through Capillary Wall and Plasma Layer" (PhD thesis) 1969. 

    6. R.M. Navari, Blood Oxygenation: 243-61, 1970. "Effect of Plasma Constituents on Oxygen Diffusivity" 

    7. T.K. Goldstick, Mass Transfer in Biological Systems: 101-
13, 1970. "Diffusion of Oxygen in Solutions of Blood Proteins"

    8. Dixon 1958, "Fatty Deposition: A Disorder of the Cell", Quart. J. Exp. Physiol. 43: 139-59.

 9. Spain 1962, ""Rabbit Local Tissue Response to Triglycerides, Cholesterol and Its Ester",  Arch. Path. 73: 82. 

10. Adams 1963, "Phospholipids in atherosclerosis: the modification of the cholesterol granuloma by phospholipid", J. Pathology & Bacteriology, 86: 431.   * 

11. Buck 1951, "Lipids of normal and atherosclerotic aortas", Arch. Path., 51: 224. 

12. Adams 1964, "Arteriosclerosis in Man, Other Mammals and Birds", BioI. Rev. 39: 372. 

13. Shore 1955 "Plasma Phospholipide Deposition and Aortic Phospholipide Synthesis in Experimental Atherosclerosis", Am. J. Physiol., 181: 527.  * 

14. ZilversmIt 1954, "The Origin of Aortic Phospholipid in Rabbit Atheromatosis", Circulation, 9: 581-5.  * 

15. McCandless 1956, "The Effect of Cholesterol on the Turnover of Lecithin, Cephalin and Sphingomyelin in the Rabbit", Arch. Biochem. Biophys., 62: 402. 

16. Adams 1963, "Histochemical observations on the localization and origin of sphingomyelin, cerebroside, and cholesterol in the normal and atherosclerotic human artery". J. Pathology & Bacteriology, 85: 113.  * 

17. Adams 1963: "The distribution of lipids and enzymes in the aortic wall in dietary rabbit atheroma and human atherosclerosis", J. Pathology & Bacteriology, 86: 42   

18. Friedkin-1948, "Oxidatlon-Coupled Incorporation of Inorgainc Radiophosphate into Phospholipid and Nucleic Acid in a Cell Free System", J. BioI. Chem. 177: 775.  * 

19. Chaikoff 1942, "The Application of Labeling Agents to the Study of Phospholipid Metabolism", Physiol. Rev. 22:  291. 

20. Adams 1962, "A Hypothesis to Explain the Accumulation of Cholesterol in Atherosclerosis", Lancet 1: 890.    * 

21. Heppner 2004,"Plasma Oxygen Permeability May be a Factor in Atherosclerosis",J Atheroscler. Thromb. 11<  * 





Searching PubMed for "hypoxia atherogenesis" yield 742 references:
http://www.ncbi.nlm.nih.gov/pubmed/?term=hypoxia+atherogenesis  

742<742    1959 
[Effect of anoxia on the development of experimental coronary atherosclerosis].     http://www.ncbi.nlm.nih.gov/pubmed/13651309   
   In Russian.  No abstract. 


736<742    1969 
Effects of hypoxia and of carbon monoxide exposures on experimental atherosclerosis   
http://www.ncbi.nlm.nih.gov/pubmed/5800302   
    No Abstract. 
    181 Related citations:   
http://www.ncbi.nlm.nih.gov/pubmed?linkname=pubmed_pubmed&from_uid=5800302   
    2 Cited by's. 


727<742    1972  * 
Plasma proteins, oxygen transport and atherosclerosis   
http://www.ncbi.nlm.nih.gov/pubmed/4115210   
    No Abstract.  Gainer & Chisolm et al. 
    104 Related citations
http://www.ncbi.nlm.nih.gov/pubmed?linkname=pubmed_pubmed&from_uid=4115210      


724<742    1974  * 
Oxygen diffusion and atherosclerosis   
http://www.ncbi.nlm.nih.gov/pubmed/4810465   
    No Abstract.    Gainer & Chisolm 
    1 Cited by. 


717<742    1975 
Effects of intermittent and continuous hypoxia on the aortic wall in rabbits.   
http://www.ncbi.nlm.nih.gov/pubmed/125091    Helin
    2 Cited by's. 


706<742    1977    *
Oxygen, the arterial, wall, and atherosclerosis.    
http://www.ncbi.nlm.nih.gov/pubmed/414524   
    No Abstract.    Jurris & Weiss
    141 Related citations
http://www.ncbi.nlm.nih.gov/pubmed?linkname=pubmed_pubmed&from_uid=414524   
   

699<742    1978 
Carbon monoxide-induced arterial wall hypoxia and atherosclerosis.   
http://www.ncbi.nlm.nih.gov/pubmed/678310   
    112 Related citations
http://www.ncbi.nlm.nih.gov/pubmed?linkname=pubmed_pubmed&from_uid=678310  


682<742    1983 
Some pathogenetic factors of age-related specificities in experimental atherosclerosis   
http://www.ncbi.nlm.nih.gov/pubmed/6617212   
    "
a) by insufficient synthesis of phospholipids in aortic tissue; ... d) growing difficulties in ensuring oxygen supply to the organism"  
    187 Related citations
http://www.ncbi.nlm.nih.gov/pubmed?linkname=pubmed_pubmed&from_uid=6617212  


681<742    1983 
Serum lipemia: an overlooked cause of tissue hypoxia.   
http://www.ncbi.nlm.nih.gov/pubmed/6365311   
     "
... serum lipemia affects the transfer of oxygen from the blood to the tissues. ... The contribution of hypoxia of the arterial wall to atherogenesis is outlined, and its adverse effects in the ischemic heart are listed."  
    1 Cited by. 


678<742    1983 
The effect of oxygen on the development of atherosclerosis in WHHL rabbits.   
http://www.ncbi.nlm.nih.gov/pubmed/6870989   
    "
From these results, we conclude that hyperoxic or hypoxic inhalation respectively regresses or aggravates the development of atherosclerotic lesions, not by an indirect action on blood lipid concentrations but by a direct action on the vascular wall."  
    2 Cited by's. 


672<742   
Effect of hypoxia on cholesterol accumulation in cultured rabbit aortic smooth muscle cells.   
http://www.ncbi.nlm.nih.gov/pubmed/6477669  
    103 Related citations
http://www.ncbi.nlm.nih.gov/pubmed?linkname=pubmed_pubmed&from_uid=6477669  


668<742    1985  * 
Mechanisms of atherogenesis: endothelial hypoxia proposed as the major initiator.    
http://www.ncbi.nlm.nih.gov/pubmed/3853084   
    "
A common factor of blood vessel hypoxia, specifically endothelial and intimal hypoxia, is shown to exist."     Boxen 
    1 Cited by. 


664<742    1987  * 
[The role of carotenoids in the development of compensatory reactions of the body to hypoxia]   
http://www.ncbi.nlm.nih.gov/pubmed/3825387   in Russian.  
    93 Related citations
http://www.ncbi.nlm.nih.gov/pubmed?linkname=pubmed_pubmed&from_uid=3825387  


658<742    1987  *  
Hypoxia and atherosclerosis: re-evaluation of an old hypothesis.   
http://www.ncbi.nlm.nih.gov/pubmed/3426659  
    3 Cited by's. 
Gainer. 


647<742    1989    * 
Endothelial hypoxia induction of atherosclerosis: an explanation of patency rates for internal mammary artery and other coronary artery bypass grafts.   
http://www.ncbi.nlm.nih.gov/pubmed/2689844    Boxen again


638<742    1991  **
Arterial wall oxygenation, oxyradicals, and atherosclerosis.   
http://www.ncbi.nlm.nih.gov/pubmed/1793456  
    My comment
This is the first, and therefore the oldest, reference found in this search mentioning "oxyradicals".   
    Searching PubMed for "oxygen free radicals atherosclerosis" found 2240 references. 
It was dated 1982:   16 search references to here. 
http://www.ncbi.nlm.nih.gov/pubmed/?term=oxygen+free+radicals+atherosclerosis     


610<742    1996  * 
Non-ischemic hypoxia of the arterial wall is a primary cause of atherosclerosis       
    2 Cited by's. 
   

591<742    1998 
Ox-LDL induces apoptosis in human coronary artery endothelial cells: role of PKC, PTK, bcl-2, and Fas   
http://www.ncbi.nlm.nih.gov/pubmed/9683446   
    My comment
This is the first, and therefore the oldest, reference to mention oxidized lipoproteins. 


584<742    1999   
Evidence of hypoxic areas within the arterial wall in vivo.    
http://www.ncbi.nlm.nih.gov/pubmed/10195911    
    Free Final Version:   
http://atvb.ahajournals.org/content/19/4/870.long   


534<742 2003
Oxidized low-density lipoprotein (oxLDL) triggers hypoxia-inducible factor-1alpha (HIF-1alpha) accumulation via redox-dependent mechanisms.
http://www.ncbi.nlm.nih.gov/pubmed/12586627
    My comment:   
Another oxLDL reference. 


527<742    2003 
Nocturnal oxygen desaturation correlates with the severity of coronary atherosclerosis in coronary artery disease.  
http://www.ncbi.nlm.nih.gov/pubmed/12970020       


520<742    2004 
Antioxidant intervention attenuates myocardial neovascularization in hypercholesterolemia   
http://www.ncbi.nlm.nih.gov/pubmed/15051643       
    Oxidative stress. 


512<742    2004 
Plasma oxygen permeability may be a factor in atherosclerosis.    
http://www.ncbi.nlm.nih.gov/pubmed/15153663   
    My paper. 



511<742   
Oxidative stress and hypoxia: implications for plasminogen activator inhibitor-1 expression   
http://www.ncbi.nlm.nih.gov/pubmed/15242559  
    More O2 stress. 


504<742    2004 
Hypoxia increases LDL oxidation and expression of 15-lipoxygenase-2 in human macrophages.   

http://www.ncbi.nlm.nih.gov/pubmed/15358603   
    More oxLDL. 


503<742    2005 
Endothelial cell superoxide generation: regulation and relevance for cardiovascular pathophysiology.  
http://www.ncbi.nlm.nih.gov/pubmed/15475499   
    More oxLDL. 
    

495<742    2005 
Repetitive hypoxia increases lipid loading in human macrophages-a potentially atherogenic effect   
http://wwwncbi.nlm.nih.gov/pubmed/15777539  
    Hopoxia. 


488<742   2005 

Sleep-apnea-related intermittent hypoxia and atherogenesis: adhesion molecules and monocytes/endothelial cells interactions.
http://www.ncbi.nlm.nih.gov/pubmed/16055132
  
    Hypoxia. 


484<742    2006 

Statins inhibit hypoxia-induced endothelial proliferation by preventing calcium-induced ROS formation.
http://www.ncbi.nlm.nih.gov/pubmed/16112121
    Both hypoxia & ROS. 

454<744    2007 
Sleep apnoea inducing hypoxemia is associated with early signs of carotid atherosclerosis in males   
http://www.ncbi.nlm.nih.gov/pubmed/16790368  
    Hypoxia. 

443<744    2007 
Hyperlipidemia and lipid peroxidation are dependent on the severity of chronic intermittent hypoxia   
http://www.ncbi.nlm.nih.gov/pubmed/17082365  
    Hypoxia causing oxLDL.  

435<744    2007 
Chronic intermittent hypoxia induces atherosclerosis   
http://www.ncbi.nlm.nih.gov/pubmed/17332479  
    Hypoxia. 

408<744    2008 
Intermittent hypoxia: the culprit of oxidative stress, vascular inflammation and dyslipidemia in obstructive sleep apnea.   
http://www.ncbi.nlm.nih.gov/pubmed/20477224  
(Click on "Clinical Key") 
    Hypoxia. 


326<744    2009 
The role of hypoxia in atherosclerosis.   
http://www.ncbi.nlm.nih.gov/pubmed/19644366   
    Hypoxia. 


226<744    2011 
Evaluation of trans sodium crocetinate on safety and exercise performance in patients with peripheral artery disease and intermittent claudication.   
http://www.ncbi.nlm.nih.gov/pubmed/22003000   
    Gainer   
    3 Cited by's   
    Free full text
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182020/  


130<744    2013 
Hypoxia in atherosclerosis and inflammation.   
http://www.ncbi.nlm.nih.gov/pubmed/23942270   
    Hypoxia. 


86<744    2014 
Cardiovascular complications of sleep apnea: role of oxidative stress   
http://www.ncbi.nlm.nih.gov/pubmed/24734153  
    Free PMC Article: 
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964889/   
    O2Stress. 


31<744    2015 
Potential contributions of intimal and plaque hypoxia to atherosclerosis   
http://www.ncbi.nlm.nih.gov/pubmed/25876920   
    oxLDL 


Searching PubMed for "sphingomyelin oxygen atherogenesis " revealed only 15 references, none of which were helpful. 

   





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