NR dos Santos full list of publications

Scopus profile

MyNCBI Bibliography

(#, corresponding authorship; *, first co-authorship)

ORIGINAL RESEARCH

1. Catarino TA, Pacheco-Leyva I, Pereira JP, Baessa M, DOS SANTOS NR# (2024) Transgenic αβ TCR tonic signaling is leukemogenic while strong stimulation is leukemia-suppressive. Under Review (Biorxiv DOI 10.1101/2024.01.17.576006)

2. Pereira JP, Ferreira F, DOS SANTOS NR#. (2024) Antibody targeting of surface P-selectin glycoprotein ligand 1 leads to lymphoma apoptosis and tumorigenesis inhibition. Hematological Oncology, 42:e3257.

3. Catarino TA, Pacheco-Leyva I, Al-Dalali F, Ghezzo MN, Fernandes MT, Costa T, DOS SANTOS NR#. (2022) Cdkn2a inactivation promotes malignant transformation of mouse immature thymocytes before the β-selection checkpoint. Experimental Hematology, 116:30-36.

4. Pereira JP, Cavaco P, da SIlva RC, Pacheco-Leyva I, Mereiter S, Pinto R, Reis CA, DOS SANTOS NR# (2021) P-selectin glycoprotein ligand 1 promotes T cell lymphoma development and dissemination. Translational Oncology, 14:101125.

5. Fernandes MT, Caroço LS, Pacheco-Leyva I, DOS SANTOS NR#. (2019) NF-κB-dependent RANKL expression in a mouse model of immature T-cell leukemia. Biochemical and Biophysical Research Communications, 510:272-277.

6. Ghezzo MN, Fernandes MT, Pacheco-Leyva I, Machado RS, Rodrigues PM, Araújo MAS, Kalathur RK, Futschik ME, Alves NL, DOS SANTOS NR#. (2018) FoxN1-dependent thymic epithelial cells promote T-cell leukemia development. Carcinogenesis, 39:1463-1476.

7.     Trinquand A*, DOS SANTOS NR*, Tran Quang C*, Rocchetti F, Zaniboni B, Belhocine M, de Jesus CC, Lhermitte L, Tesio M, Dussiot M, Cosset F-L, Verhoeyen E, Pflumio F, Ifrah N, Dombret H, Spicuglia S, Chatenoud L, Gross D-A, Hermine O, Macintyre E, Ghysdael J, Asnafi V. (2016) Triggering the TCR developmental checkpoint activates a therapeutically targetable tumor suppressive pathway in T-cell leukemia. Cancer Discovery, 6:972-985.  

8. Fernandes MT, Ghezzo MN, Silveira AB, Kalathur RK, Póvoa V, Ribeiro AR, Brandalise SR, Dejardin E, Alves NL, Ghysdael J, Barata JT, Yunes JA, DOS SANTOS NR#. (2015) Lymphotoxin-β receptor in microenvironmental cells promotes the development of T-cell acute lymphoblastic leukaemia with cortical/mature immunophenotype. British Journal of Haematology, 171:736-751.

9. Mouffouk F, Simão T, Dornelles D, Lopes AD, Sau P, Martins J, Abu-Salah KM, Alrokayan SA, Rosa da Costa AM, DOS SANTOS NR#. (2015) Self-assembled polymeric nanoparticles as new, smart contrast agents for cancer early detection using magnetic resonance imaging. International Journal of Nanomedicine, 10:63-76.

10.  DOS SANTOS NR, Williame M, Gachet S, Cormier F, Janin A, Weih D, Weih F, Ghysdael J. (2008) RelB-dependent stromal cells promote T-cell leukemogenesis. PLoS ONE, 3:e2555.

11.  Medyouf H, Alcalde H, Berthier C, Guillemin MC, DOS SANTOS NR, Janin A, Decaudin D, de Thé H, Ghysdael J. (2007) Targeting calcineurin activation as a therapeutic strategy for T-cell acute lymphoblastic leukemia. Nature Medicine, 13:736-74.

12.  DOS SANTOS NR, Rickman DS, de Reynies A, Cormier F, Williame M, Blanchard C, Stern MH, Ghysdael J. (2007) Pre-TCR expression cooperates with TEL-JAK2 to transform immature thymocytes and induce T-cell leukemia. Blood, 109:3972-3981.

13.  DOS SANTOS NR, Ghysdael J. (2006) A transgenic mouse model for TEL-JAK2-induced B-cell lymphoma/leukemia. Leukemia, 20:182-185.

14.  Dumortier A, Jeannet R, Kirstetter P, Kleinmann E, Sellars M, DOS SANTOS NR, Thibault C, Barths J, Ghysdael J, Punt JA, Kastner P, Chan S. (2006) Notch activation is an early and critical event during T-cell leukemogenesis in Ikaros-deficient mice. Molecular and Cellular Biology, 26:209-220.

15.  de Bruijn DRH*, DOS SANTOS NR*, Kater-Baats E, Thijssen J, van den Berk L, Stap J, Balemans M, Schepens M, Merkx G, Geurts van Kessel A. (2002) The cancer-related protein SSX2 interacts with the human homologue of a ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP. Genes, Chromosomes and Cancer, 34:285-298.

16.  de Bruijn DRH, DOS SANTOS NR, Thijssen J, Balemans M, Debernardi S, Linder B, Young BD, Geurts van Kessel A. (2001) The synovial sarcoma associated protein SYT interacts with the acute leukemia associated protein AF10. Oncogene, 20:3281-3289.

17.  DOS SANTOS NR#, de Bruijn DRH, Kater-Baats E, Otte AP, Geurts van Kessel A. (2000) Delineation of the protein domains responsible for SYT, SSX and SYT-SSX nuclear localization. Experimental Cell Research, 256:192-202.

18.  DOS SANTOS NR#, Torensma R, de Vries TJ, Schreurs MWJ, de Bruijn DRH, Kater-Baats E, Ruiter DJ, Adema GJ, van Muijen GNP, Geurts van Kessel A. (2000) Heterogeneous expression of the SSX cancer/testis antigens in human melanoma lesions and cell lines. Cancer Research, 60:1654-1662.

19.  Geurts van Kessel A, de Bruijn D, Hermsen L, Janssen I, DOS SANTOS NR, Willems R, Makkus L, Schreuder H and Veth R. (1998) Masked t(X;18)(p11;q11) in a biphasic synovial sarcoma revealed by FISH and RT-PCR. Genes, Chromosomes and Cancer, 23:198-201.

20.  DOS SANTOS NR#, de Bruijn DRH, Balemans M, Janssen B, Gärtner F, Lopes JM, de Leeuw B and Geurts van Kessel A. (1997) Nuclear localization of SYT, SSX and the synovial sarcoma-associated SYT-SSX fusion proteins. Human Molecular Genetics, 6:1549-1558.

21.  Soares P, DOS SANTOS NR, Seruca R, Lothe RA and Sobrinho-Simões M. (1997) Benign and malignant thyroid lesions show instability at microsatellite loci. European Journal of Cancer, 33:293-296.

22.  DOS SANTOS NR, Seruca R, Constância M, Seixas M and Sobrinho-Simões M. (1996) Microsatellite instability at multiple loci in gastric carcinoma: clinicopathologic implications and prognosis. Gastroenterology, 110: 38-44.

23.  Seruca R, Constância M, DOS SANTOS NR, David L, Queimado L, Carvalho F and Carneiro F. (1995) Allele loss in human gastric carcinomas: Relation to tumor progression and differentiation. International Journal of Oncology, 7: 1159-1166.

24.  Seruca R, SANTOS NR, David L, Constância M, Barroca H, Carneiro F, Seixas M, Peltomaki P, Lothe R and Sobrinho-Simões M. (1995) Sporadic gastric carcinomas with microsatellite instability display a particular clinicopathologic profile. International Journal of Cancer, 64: 32-36.

REVIEWS